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MITOSIS / MEIOSIS

Marcia Puchi 2011

División nuclear División citoplasmática .

MEIOSIS .

Fecundación .

2n Apareamiento entrecruzamiento Permutación The two daughter cells contain a haploid number of chromosomes (but a diploid amount of DNA) .

n n .

Dos principales fuentes de variabilidad durante la meiosis 2n different haploid gametes 223 = 8. between two and three crossover events occur on each pair of human chromosomes .4 × 106 On average.

sintetizan y unen. complejos enzimáticos que cortan.Entrecruzamiento Recombinación. .

The error rate increases with advancing maternal age .Errores en la meiosis: No disyunción de los cromosomas a) Síndrome de Down (47 cromosomas): trisomía del par 21 b) Síndrome de Klinefelter (47 cromosomas): XXY c) Síndrome de Turner (45 cromosomas): XO The frequency of missegregation in human oocytes is remarkably high (about 10% of meioses). and this is thought to be one reason for the high rate of spontaneous abortions in early pregnancy.

FECUNDACIÓN .

Ovogénesis Entrada en fase M meiosis the primary oocytes synthesize a coat and cortical granules Señal hormonal .