Brand Name: Nootropil Generic Name: Piracetam Indications: Cerebral insufficiency and chronic manifestation of CVA, post traumatic

syndromes, severe mental cloudiness and vascular coma of a traumatic of toxic origin, chronic alcoholism and addiction, pre-delirium, chronic vertigo of peripheral or central origin, pediatric therapy e.g. dyslexia in children, involutional syndromes related to aging, cortical myoclonus. Drug Classification: Neuromuscular agent Mechanism of action: Piracetam acts selectively upon telencephalon by improving its associative function. It increases the energy output of the brain cell and activates its neurophysiological potentialities, especially in deficit conditions. Nootropil is virtually nontoxic and has no stimulating, sedative or neurovegetative activities. Dosage: CVA: 4.8-6g/day Children 8-13y/o with learning difficulties: 3.3 g/day in 2 divided doses or 5ml of a 33% solution bid. Myoclonus or cortical in origin-Dose range: 7.2-24 g/day. Initially 7.2g/day increasing by 4.8 g/day every 3 days bid-tid.

Chronic Vertigo:1.2-2.4 g in 2-3 divided doses Special Precaution: renal insufficiency, underlying haemostatic disorders, major op or severe hemmorhage, long term treatment in elderly, abrupt discontinuation in myoclonic patients. Pregnancy Risk Category: Adverse reaction: Hyperkinesia, weightr gain, asthenia, nervousness, agitation, irritability, anxiety and sleep disturbances, fatigue or drowsiness, GI disturbances. Contraindication: Cerebral hemmorhage, end stage renal disease. Form: Capsule, tablet, granules, oral solution, injection, infusion Nursing Responsibilities:  Monitor heart rate, ECG and BP periodically throughout the therapy.  Drug has strong taste. Mixing oral form with orange juice mask the taste.  Assess patient to clear airway  Provide support ventilation, if it is needed.  Assess and support cardiac function.  Reassure patient that communication abilities will return as the medication wears off.

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