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Pathophysiology

Pathophysiology

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Published by: Jeremiash Noblesala Dela Cruz on Oct 03, 2013
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10/03/2013

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PATHOPHYSIOLOGY

Site (gastroduodenal mucosa)

Inability to withstand the digestive action of gastric acid (HCl) and pepsin

Increased concentration or activity of acidpepsin and decreased resistance of the mucosa

Erosion/damage of the mucosa

Inability to secrete enough mucus to act as a barrier against HCl

hypersecretion of gastric juice, duodenal ulcers, and gastrinomas (islet cell tumors) in the pancreas

Epigastric pain

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