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OSPE 2548-2551

PQ 191 Rx CU 65 et al.

OSPE (Objection Structured Pharmaceutical Examination)

station ( lab )
30 station () 5 25

(1 10 4 )
3 () 100

OSPE 80 ( !!)

clinic, ceutic,
4 . 1.
2.
- 3.


4.

( )
OSPE lab
,

100% (2551) 92%


1 ( )

OSPE

, , , (), (), ( ),
, , New Light

(), (USA)
5

..

OSPE 2548

25

14

( )

11

Part 1
14

(- )
...

OSPE

( 0 )

: MDI

(
)

Salbutamol 1

puff tid


..

: ... (

: ) ....
Salbutamol

1 3 --

1.

3.

2.
4.

5.
6.
7.
8.


10

: ()
:

:

MDI

2
:

28 (
28 )


..

: ....

/
( antibiotic) (
)

: // 24 /
/

: ..

28 28
21 7

..

:
:

1 15


2-3

( ....

.... 1

.... 2

: vanishing cream
Calamine powder

Vanishing cream add to

10

: digital 1 ,

, Spatula 2 , 2 1

:
1.

Cream 10 -1 = 9

2.

3.

?
4.

Tare

0.000

5.

Stainless spatula 2

1 Vanishing cream

. triple check

6.

Tare 1

0.000 off

: Vanishing cream cream


- spatula 2 3
spatula


spatula

spatula
Tare
Triple Check

Self-conquest is the greats of victory.

4 ( 3)

: calamine cream
: 1 , calamine powder 1 , slab &

spatula, mineral oil, glycerin

Set slap & spatula (

spatula slab
)

Calamine powder (1) (2)

slab (3) = (triple check)

Spatula

(
)

Glycerin 3-4

calamine powder

Spatula 1-2 Spatula


vanishing cream

Vanishing cream slab

spatula

Vanishing cream

geometric dilution

Spatula

Spatula cream

Vanishing cream o/w (

4 vanishing cream water


phase oil phase) Glycerin
w/o mineral oil

levigating agent
Triple check

: 1 ( Primolut-N )

2 zip

: .... (

//
? )

: 45 / 3

15 ( 7)
:

( 2-3 ) 1
2 2-3

: ( ..) 14

(14 12 7-8-9-10-11-12-13 14

2-3 )
14
21 28

: lipid profile
LDL

Total cholesterol
Triglyceride
HDL

210
180
45

lab

: lab
:

...

: LDL

: lab
: ( TC =

LDL+HDL+VLDL VLDL = TG/5 LDL = 129


:

: LDL 100
Triglyceride 150 cholesterol
200

: ... Triglyceride (

: fibrate Gemfibrozil

Triglyceride (
)

Cholesterol ( Steroid )
: ..

7 Calibrate
: calibrate dropper ( 0.4 ml )

: , , dropper Cylinder
5, 10 ml

10 ...
...


i.
ii.

ml ......

0.4

ml ......

Cylinder 5 ml

2 ml 4

Cylinder 2 ml
Dropper

iii.

..
iv.

Cylinder 2 ml
cylinder

( check

v.

vi.
vii.

..... ..Net 10

,
, ACEI (Enalapril) ( )

( :

( Dextromethorphan 1 3

(
Dextromethorphan
bradykinin
)
9

2 Phentermine
2

( MIMs )

MIMs

10 Paracetamol tablet 100

Paracetamol CPM

Triple Check

Alc

5
Check

11 KI 2 %
1

, Digital, KI, +
,

100 ml

KI 2

50

ml

KI (50 2)/100 = 1

( ?)

12 KI (
31)

Cylinder ,

Stirring rod,

KI

2/3 ( )

Cylinder

Solution Cylinder rins

13

Steven Johnson Syndrome,

Bractrim

10

14 ()

Nifedipin SR ( : )

ASA 1 3 (: 1
)

10

11

3 : MIMs,Drug
information,Martindale,USP : Tablet,

capsule(Soft or Hard), Lozenge, Suspension, Emulsion,pills


: , ,
,

: ,

(NSAIDs),

(Cimetidine) : Antibiotic dry syrup,


OSPE 2549
21

.
AST

30 (0-35)

AntiHAC

negative

AntiHCS

negative

ALT
AntiHBS

.()
negative

-
-

-
-
(



22

23

Cystitis

BPH 26

10
24


A - ORS 1

B - ambroxal 1 10
C - Bromhexine 1 10
D - Disento 1 4

E - Paracetamol 1 10

B C D

A E

)
25
-



MDI

26

- 2

(+ )(3
)..

1
2
3

Amoxy+K.clavulonate 500 mg q 8 hr pc
Chloramphenicol eye drop O.U

#20
#1

- Amoxy 250
-

Amoxy

Amoxy

Chloram

27

28

- 1
-

BMI ---


Phentermine

P2

29
.

..

. 30

.. .
/

.. 2-3

..

..

1. Roxithromycin 150 mg
2. Actifed

3.

30

31
-

- 5

1. 1 60

2. Phenylbutazone
3. Lomatil Dramamine

4. Prednisolone Cream
5. Dexamethasone

+
+

1.

100

Suppositories Vaginal Tablet


2

2. ENO Effervescent Powder

3. SARGITA Lozenges

4.

Mixture

5. vial Dry powder for injection

MDI
NTG

Diazepam

atarax

5 DIS
-

Dose / regimen
Interferon 2B

- 2
-

Druginformation Handbook Injection Drug


Vancouver

4-5

.
6

7 Aliquat

-
-

Tetracyclin 2 % 25 ml
Tetracyclin 250 mg

- 2
8

tetracycline
Tetracyclin 25 ml 2 %

Tetracycline

-
-

-

-
-

Tetracycline

- 16
- 32
-

16

16

- 28
- 64

10

-
-

-
-

-
-

11

-
-
-

regimen

Amoxy 20 mg/kg q 8 hr amoxy 125mg/5ml

- ---

12

13


14

15

slap + spatula

glycerin/ mineral oil .

16

- 90
- +

17 /
-

atorvastatin

18

1. Marvilon 28
2. Doxycyclin

- - .

19

DM
Hypoglycemia

20 DIS
Remington Polibase

1. Remington 2. Mims 3.

OSPE 2550

Version 1

1. dosage form 5

sugar coated tablet 2 effervescent tablet

3 mixture 4
syrup 5 lozenge

2. Advil
generic martindale,mims
drug information handbook

martindale generic ibuprofen

mims
3. isodil SL

4.

1 , mebendazole 1 , Actifed 1 , ambroxol 1

, vit.c 100 mg 1

5. amoxy ....................amoxy dry syrup


125mg

+ (
0.5 )

6. clohexidene10% clohexidene
1% 30ml

7. dilute
8. 90 CPM

9. vanishing cream (
qs.ad )

10. levigate + levigating agent glycerin


mineral oil ( glycerin )

11. codeine11 mg pheno 5 ml


12. carbopol ( carbopol


carbopol )
carbopol 10%w/w
Water qs.ad 100 g

M.ft. hydrogel 30 g

13. carbopol pH
glycerin triethanolamine (
triethanolamine )

14. 2 diclofenac SR

sustained released

antacil

15. + ?(
) ,
, , , ...............

steroid

16.
brown mixture 240ml
phenylbutazone
amitriptyline

alprazolam
lomotil

17. yellow ointment


martindale , Remington,

18. 3
amoxycillin ampicilllin

case + , .....

19. norfloxacin domperidone +


20. glibenclamide lab

FBS 200 HbA1c 9%,

21. ergotamine caffeine


2 flunarizine 2


22. 1 4 Glipizide,

metformin, aspirin, simvastatin regimen , DI


23. fluoxetine diazepam

24.

TB )


25. consult DI

DI

erythromycin + theophylline

........ penicillin

Version 2
1

Generic Name Asaphen

1. Drug Information

2. MIMS
3. ASFH

MIMS.

MIMS Thai Drug Information


ASFH
Generic Name
Trade Name MIMS
...................................................................
Generic Name

..........................

.............................

Edition...

Trade Name

..........................

1. .............................

Edition...

2. .
2
(ISDN) SL 30 prn.

.............................

.............................

Isosorbide Dinitrate

SL = Sublingual

1. .............

2.
ISDN mg

3. 1
5 1 3 2
. 3
ex

3 Amoxy (Ibiamox 125 mg./5ml) .. 6


6 mg/day

..................................................
..............................................

..

..........................................

......................

..

....................................... ( )
4

.........................................

Ceutic

Cetylpyridinium Cl 10% ml
Cetylpyridinium Cl 1% 30 ml.


Ex

N1V1

= N2 V2

10 x V1 = 1 x 30
V1 =

3 ml

technique

1. Cetylpyridinium Cl 10% --- ---


----

2. Cylinder 10 ml 3 ml.

beaker
Cylinder

3. 3 ml beaker 50 ml 30 ml
beaker

4. H2O x 27 = 20 ml
Cylinder 25 ml

5. beaker ---- stirring rod.


6. Cylinder 30 ml ( 50 ml.) H2O

30 ml. ( rinse beaker


)

7. beaker stirring rod ---



7 Paracetamol 500 mg # 90


1.

2.

3. ( 3
)

4. 5
5.

check
8 Vanishing Cream
g.

, Cream base qs. 5 g.

Rx Sulfur

0.5

Cream

- + & label

- , tare, , tare (
)

- Stirring rod spatula Cream


cream

- ** tare *

....................... Cream ...................................

9 Cream Sulfur
+ glycerin Mineral oil

Cream, ointment
Slab Spatula Pulverization by

intervention interventing agent


cream base

- Vanishing Cream Cream base O/W


glycerin

- slab glycerin smooth


paste

- cream slab geometric

dilution

10 Rx ..(Codein _ mg + Ph.
_mg) # 30

codein

3

..
Side effect

1.

2.

11 hydrogel 30 g carbopol

Px.

Carbopol 0.5% w/w

H2O qs to 100 g


( )

carbopol
30 g gel

1.
carbopol

beaker + stirring rod

Carbopol carbopol
()

2. 30 ml

carbopol carbopol pdt


------------------------------
--------------------------

12 triethanolamine (TEA) glycerin


carbopol form gel

technique
ceutic

- TEA 2-3 carbopol


gel

- PH ** PH paper gel
stirring rod check technique
gel carbopol form gel pH

13 555

1. Actifed 20

- pseudoephedrine

2. Victamin C 10
-

3. Paracetamol 500 mg 10
-

4. Ambroxol Bromhexine

14

( step )
1. ---- -----
2.
3.

- ---
Steroid 2
agonist

- -----
normal flora

4.

15

1. Lomotil

Diphenoxylate HCl + atropine sulfate

- 3 ...


2. Alprazolam

4
-

3. Pseudoephedrine 60 mg

2
-

pseudo

4. 2 ....
Codein ----- 3

16
----
1. ----
2. ----

3. ---- +
Amoxy

4. ---- Amoxy

5.

6. Case

Guide

17 glibenclamide 10 Lab

Lab

FBS

HbA1c =

200 mg/dL.

10%

1. ----
2. Lab
3.

- FBS < 120 mg/dL. & HbA1c < 7%

- FBS HbA1c
FBS

HbA1c Hemoglobin ()
3 FBS
1-2 HbA1c

- +

18 , side effect
()

. . HN 12345
Cafergot (Ergotamine 1 mg + caffeine 100 mg)
Sig 2 tabs & 1 tab q hr.
Cinnarizine 25 mg.
Sig 1 cap tid.hs

# 10s

# 10s


--- Migraine
2

1. Cafergot 10 migraine

2 1
6

10
Caffeine

2. Cinnarizine 25 mg

...

19
Metformin
1x1

# 30s

pc

Aspirin 60 mg
2 x 3 pc

Simvastatin 10 mg

# 30s
# 30s

1 x 1 Q.A.M.

1. Metformin

Metformin 500 mg.

2. Aspirin

Aspirin 60 mg.

1 x 1 pc.

3. Simvastatin
1 x 1 Q.A.M.

Simvastatin 10 mg.
1 x 1 hs.

20

Fluoxetine
Diazepam

1x1

1x1

hs.

...

Diazepam

Fluoxetine

side effect
Diazepam

21
----

- ---
- -----

- ----
- ------

- ------

- -----

- AIDS -----

- ???

22
Erythromycin

2-3 Theophylline
Budesonide 1 puff

tid

Theophylline

erythromycin enz. inhibitor


Theophylline

Theophylline narrow therapeutic side effect


S/E Caffeine


roxithromycin
Cimetidine

Theophilline
inducer

23 Sulfadiazine

yellow ointment yellow ointment


martindel , Phamaceuticsl Excipient

yellow ointment

24 Dosage form ( technical term)


1. ( sugar coated film coated
)

Coated Tablets

2. 5 Effervescent tablets
3. Mixtures
4. Lozenges

5. Emulsions
Dosage form S

25 Antacid

.......................

-
- Antacid gel

.....

Technique
OSPE (

)
...

OSPE 2550

1. Calcium
(effervescent)

2. 28

3. Lomotil,
Carbamazepine, Loratadine, Codeine , Amitryptiline

4. talcum ( )
5. talcum dusting powder

6.
7. CPM 20 +

8. digoxin
9.
SARA, Acetylcystein, Antacin ,Actifed ,ORS

10. Gel, suspension, vaginal


tablet, syrup, soft gelatin capsule

11. Isotretinoin

12. Ofloxacin Alum milk Sucralfate

13. tegaserod MIMS ?

14.

15. Erythromycin

16. Lab lipid profile


17.

18. drop

19.
Glipizide Chorlestyramine

20. Metronidazole Suspension

21. Smoot
paste

22. Metronidazole suspension


23. Carfergot + Flunarizine

24.
Aspirin

25. Phentermine

OSPE 2551

1. Metronidazole suspension

Metronidazole 1 fluid oz. (= 30 ml


)

2. 1 Metronidazole

syrup

(, , ,

3. 2 syrup

4. Metronidazole

Metronidazole ( ) ,
,

5. Phentermine

, BMI

, ? ,
phentermine, fitne

6. ,
,

7. Aspirin ,

( !!)

8.


phenytoin

9.

Enalapril, HCTZ

10. omeprazole

, omeprazole
,
(pellet) omeprazole NG tube

11. Humulin 70/30

12. goats thorn

( )
tragacanth
.

13.

Marvelon Amoxycillin

(
beta-lactamase
!!!!

14.

15. Lab

AST, ALT
,

pyrazinamide

16. vitamin B complex 30

17.
o/w

18. Iodine levigating agent , mineral oil


iodine levigate

iodine smooth paste levigate


( mineral oil
smooth paste )

19.

, () , ,
, ,
,
med error

20. 4 ? vaginal

tablet, mybacin, vitamin gel

21. Codeine

codeine
?

22. (

phentermine, prednisolone, Actifed, , codeine, steroid,


fluoxetine, benzodiazepines lorazepam, alprazolam
)

23. 25

, , ?
()

OSPE ()

1. capsule amoxicillin 500 mg 50

( amoxicillin 250 , 500 mg)

2. .........................
pregnancy risk factor

( MIMs, drug information, drug use in


pregnancy )

3.
(accuhaler)

4. Roaccutane

17 2 1
?

............. Roaccutane

5. Methronidazole 32 mg/ml suspension 25 ml

Methronidazole 400 mg

Methronidazole

: Diazepam 5 mg 2
Glycerin qs

Vehicle ad qs

25 ml

6.

: Diazepam 5 mg 2

glycerin paste

7.
vehicle

rinse
8.
9. DRP
Rx

hs

Aspirin

QAM

glibenclamide

1*1 pc
10.

Lasix

40 mg
60 mg
5 mg

S = special control drug


E-D = external use dangerous drug

P4 = psychotropic substance schedule 4


D = dangerous drug

NDD = nondangerous drug


N3 = narcotic drug schedule 3

E = external use nondangerous drug

Phenylbutazone

Prednisolone cream

Lorazepam
Acyclovir

Alum milk

11. : ( urticaria )
:

22


.....
urticaria

12. :
: Dexoph

26


13. alcohol 20 % 50 ml alcohol 80 %
100 ,50, 25, 10 ml 100 500
pipet

50 ml volumetric flask

stirring rod

N1V1 = N2V2
20*50 = 80*V2

v2 = 12.5 ml

14. 51

TG

Total cholesterol 267 mg/dl

LDL

HDL

135 mg/dl

167 mg/dl
67 mg/dl

simvastatin 10

15. Drug interaction consult


Rx

Erythromycin
CPM

Theophyline
Salbutamol

Erythromycin Theophyline Erythromycin Enz. Inhibitor


Theophyline
Theophyline

16. 40 Haldol Midazolam 1


Haldol

Midazolam P2

17. dosage form


Effervescent

film

Suppository

Turbuhaler

Lozenges

18. vanishing cream


Chloramphenicol 0.5 g
vanishing cream

qs 5 g

vanishing cream 4.5 g


19. cream base

20. warfarin S/E


21. Theophyline SR

22. 18 4
..
25 ..

23. Amphotericin B NSS

24.
Paracetamol syrup 120 mg/ml

Paracetamol tab 100 tab


50 tab
0.1 %

Amoxicillin dry syrup

counter pain plus


dimenhydrinate
T.A. cream

120 ml

Mebendazole 100 mg 6 tab


5

Aspirin grain 5 10 tab

25. 3 20 kg amoxicillin dry syrup


Coamox 125 mg/5ml 60ml , Coamox 250mg/5ml 60ml