Competitive inhibition

Diagram Before: After:

1. 2. 3. 4.

Has a similar shape to the substrate Has a complementary shape to the active site Binds to the active site Prevents the formation of enzyme-substrate

complexes

Graph Description 1. Reaches the same maximum rate as without inhibition 2. But at a higher substrate concentration 3.

Non-competitive inhibition
Diagram Before: After:

1. 2.

Binds to the enzyme away from the active site Causes a change in the tertiary structure of

the enzyme 3. 4. Changes the shape of the active site Prevents the formation of enzyme-substrate

complexes
Graph Description 1. Rate of reaction is lower for all substrate concentrations 2. Maximum rate of reaction is lower 3.