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Question 1
1.

Innate immune responses to tumor include


Answer

Macrophage cytotoxic T cells B cells helper T cells Dendritic cell


1 points

Question 2
1.

Which types of immune cells could suppress T cell response to tumors


Answer

NK cell macrophage CTLs B cells regulatory T cells


1 points

Question 3
1.

Which antigen belongs to oncofetal antigens


Answer

Tyrosinase mutated p53 Her-2/neu AFP SV40 T antigen


1 points

Question 4
1.

Adaptive immune responses to tumor include:


Answer

Macrophage NK cell cytotoxic T cells cytokine components


1 points

Question 5
1.

Which types of immunotherapy belong to passive immunity


Answer

Dendritic cell based therapy vaccine IL-2 treatment enhancing costimulator expression in tumor cells Adoptive cellular therapy
1 points

Question 6
1.

Which cytokine could be produced by tumor and suppresses anti-tumor immunity:


Answer

IL-2 GM-CSF TGF-beta IL-12 TNF


1 points

Question 7
1.

Which virus infection is associated with nasopharyngeal carcinoma


Answer

HBV HCV EBV HPV

HIV
1 points

Question 8
1.

Which type of response belongs to humoral immunity:


Answer

Cytokine antibodies T cells macrophage chemokines


1 points

Question 9
1.

Which type of cells have immune suppressive function:


Answer

Dendritic cell Macrophage NK cell cytotoxic T cells MDSC


1 points

Question 10
1.

Tumor associated antigens do not expressed on normal cells.


Answer True False 1 points

Question 11
1.

Oncogenic viruses include both DNA and RNA viruses.


Answer True False 1 points

Question 12
1.

NK cells could not kill tumor cells with the absence of MHC-I expression.
Answer True False 1 points

Question 13
1.

CD8+ T cell responses specific for tumor antigens may require cross-presentation of tumor antigens by APCs
Answer True False 1 points

Question 14
1.

CD4+ T cells could kill tumor cells directly


Answer True False 1 points

Question 15
1.

Regulatory T cells may enhance T cell responses to tumor.


Answer True False 1 points

Question 16
1.

Certrain products of tumor cells could suppress anti-tumor immune responses.


Answer True False 1 points

Question 17
1.

Dendritic cell based immunotherapy belong to passive immunotherapy.


Answer True False 1 points

Question 18
1.

Tumor antigens recoganized by CTLs are the principle inducers of and targets for antitumor immunity.
Answer True False

1 points

Question 19
1.

Tumor cells are usually weakly immunogenic.


Answer True False 1 points

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