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Oral Mucosa

Oral Mucosa

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Published by Rosette Go

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Published by: Rosette Go on Oct 17, 2009
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11/14/2012

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ORAL MUCOSA • Uninterrupted mucous membrane which is continuous with the skin near the vermilion border of the

lips and with the pharyngeal mucosa in the region of the soft palate and anterior pillar of fauces • Epithelium of oral mucosa originates from ECTODERM except for TONGUE  ECTODERM SECRETION o

  

Taste buds Reflexes Thirst response

SALIVA  Viscous fluid for maintenance of a moist surface

3 TYPES OF MUCOSA • MASTICATORY MUCOSA

PERMEABILITY AND ABSORPTION o Certain drugs are successfully absorbed when held under the tongue

o

Comes in primary contact with food during mastication Keratinized

THERMAL REGULATION o Only for animals like DOGS and not applicable to humans

o o

Areas of free gingiva & attached gingiva; hard palate

LINING MUCOSA o Doesn’t function in mastication; has little attrition Soft, pliable & non-keratinized Lips, cheeks, vestibule, floor of the mouth, inferior surface of the tongue, soft palate

GENERAL HISTOLOGIC CHARACTERISTICS OF ORAL MUCOSA • ORAL EPITHELIUM o • Stratified squamous epithelium

o o

LAMINA PROPRIA/CORIUM o Underlying connective tissue layer

SPECIALIZED MUCOSA o Covered largely with cornified epithelial papilla Dorsum of the tongue •

CONNECTIVE TISSUE PAPILLAE o Irregular and upward projections of connective tissue Interdigitates with EPITHELIAL PEGS

o

o FUNCTIONS OF ORAL MUCOSA • PROTECTION o Separates and protects deeper tissues and organs in the oral region Acts as major barrier to surface abrasions and normal flora of the oral mucosa • •

RETE PEGS o Epithelial pegs/ridges that interdigitates with connective tissue papillae

BASEMENT MEMBRANE o Structureless layer in between connective tissue and epithelium

o

SENSATION o Provides considerable information about events within the oral cavity    Temperature Touch Pain

MUCOPERIOSTEUM o Provides firm, inelastic attachment of oral mucosa directly to the periosteum of underlying bone without intervening submucosa Binds mucosa to the alveolar process or palatine bone

o

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STRATUM GRANULOSUM


HISTOLOGIC CHARACTERISTIC OF ORAL MUCOSA • SURFACE EPITHELIUM TYPES o NON-KERATINIZATION  STRATUM SUPERFICIALE  • Slightly more flattened than in the preceding layers Contain dispersed tonofilaments and nuclei Non-keratinized epithelium Flexible and tolerant of both compression and distention 

Larger flattened cells containing small granules called KERATOHYALIN GRANULES FLAGGRIN & LORICRIN proteins

STRATUM SPINOSUM • Larger elliptical/spherical cells DESMOSOMES/ INTERCELLULAR BRIDGES

o

Points where the stratum spinosum remain in contact with each other

STRATUM INTERMEDIUM • Slight increase in cell size well as accumulation of glycogen in cells of the surface layer

STRATUM BASALE • Cuboidal or columnar cells adjacent to the basement membrane Aka GERMINATIVE LAYER

STRATUM BASALE • Cuboidal or columnar cells containing separate tonofilaments and other cell organelles Site of most cell division o

ULTRASTRUCTURE OF EPITHELIAL CELLS   TONOFILAMENTS INTERCELLULAR BRIDGES/DESMOSOMES

• o

KERATINIZATION  TYPES: • • • ORTHOKERATINIZATION PARAKERATINIZATION INCOMPLETE PARAKERATINIZATION •

LAMINA PROPRIA/CORIUM o PAPILLARY LAYER/CONNECTIVE TISSUE PAPILLA  PEGS o Interdigitates with RETE

RETICULAR LAYER  Densely arranged connective tissue fibers

STRATUM CORNEUM • Outermost keratinized layer SQUAMES o Do not contain any nuclei

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-Rosette Go 031909 

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