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Published by: ianecunar on Oct 17, 2009
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Brand name: Combivent Generic name: Ipratropium Indication: Maintenance therapy of reversible airway obstruction due to COPD, common

colds Drug classification: anticholinergics, bronchodilators Mechanism of action: blocks the action of acetylcholine at parasympathetic sites in bronchial smooth muscle causing bronchodilation Dosage: Adult: 2puffs qid, Adult and children > 12yr 1 vial every 6-8 hr, Child 2-12yr 3drops/kg/dose q6-8 hrs Special precaution: patients with bladder neck obstruction, prostatic hypertrophy, urinary retention, geriatric patients, pregnancy, lactation children <5 yrs old Pregnancy risk category: B Adverse reaction: CNS: dizziness, headache, nervousness GI: GI irritation nausea Derm: rash CV: hypotension, palpitations Others: allergic reactions, blurred vision, sore throat, epistaxis, nasal irritation Contraindicated to: Hypersensitivity to ipatropium, atropine, belladonna alkaloids, bromide or flurocarbons, peanut or soy allergy, avoid use during acute bronchospasm

Form: Aerosol inhaler, inhalation solution, nasal spray Nursing responsibilities:  Monitor HR, PR, RR  Caution to those with heart problems and overactive thyroid  Assess allergy to atrophine and belladonna alkaloids

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