DRUG

DOS E 50 mg q8 hrs

ROUT E IV

INDICATION S Short-term treatment of active duodenal ulcer Short-term treatment of active, benign gastric ulcer Maintenance therapy for duodenal ulcer at reduced dosage. Short-term treatment for GERD. Pathologic hypersecretory conditions (ZollingerEllison syndrome)

CONTRAINDICATION

ACTION

SIDE EFFECT CNS: headache, malaise, dizziness, somnolence, insomnia, vertigo CV: tachycardia, bradycardia Dermatologic: rash, alopecia GI: constipation, diarrhea, nausea and vomiting, abdominal pain, hepatitis GU: impotence or decreased libido

Generic Name: Ranitidine Hydrochlorid e Brand Name: Zantac Class: Histamine2 antagonists

Contraindicated with allergy to ranitidine, lactation Use cautiously with impaired renal or hepatic function, pregnancy

Competitively inhibits the action of histamine at the H2 receptors of the parietal cells of the stomach, inhibiting basal gastric acid secretion and gastric acid secretion that is stimulated by food, insulin, histamine, cholinergic agonists, gastrin and pentagastrin.

NURSING CONSIDERATION S Assessment: 1. History: allergy to ranitidine, impaired renal or hepatic function, lactation, pregnancy. 2. Physical: skin lesions, orientation, affect, liver evaluation, abdominal examination, normal output, renal function tests, CBC Interventions: 1. Administer oral drug with meals and at bedtime. 2. Decrease doses in renal and liver failure. 3. Provide concurrent antacid therapy to relieve pain. 4. Administer IM

sour stomach Hematologic: leucopenia. Arrange for regular follow-up including blood test. thrombocytop enia. 5. granulocytope nia. to evaluate effects. . pancytopenia dose undiluted.Treatment of erosive esophagitis Treatment of heartburn. deep into large muscle group. acid indigestion.

Physical: orientation. History: allergy to metoclopramide. Monitor BP carefully during IV administration. mechanical obstruction or perforation. arrange for alterations in insulin dose or timing if diabetic control is compromised by . accelerates gastric emptying SIDE EFFECT CNS: restlessness. Monitor diabetic patients.DRUG Generic Name: Metoclopramide Brand Name: Maxolon Class: Antiemetic. insomnia. action of pregnancy. or pancreatic Epilepsy secretions. acetylcholin GI: nausea renal impairment e. perforation biliary. fatigue. GI stimulant DOSE 1 amp q 8 hrs ROUTE IV INDICATIONS Disturbances of GI motility Relief of symptoms of acute and recurrent diabetic gastroparesis Nausea and vomiting Metabolic diseases Short-term therapy for adults with symptomatic gastroesophage al reflux who fail to respond to conventional therapy. CV: appears to transient Use cautiously with sensitize hypertensio previously detected breast tissues to n cancer. depression. affect. lactation. dizziness. epilepsy. normal output. relaxes and diarrhea pyloric sphincter. GI hemorrhage. 2. bowel sounds. CONTRAINDICATIONS Contraindicated with allergy to metoclopramide ACTION Stimulates motility of upper GI GI hemorrhage tract without stimulating Mechanical obstruction or gastric. drowsiness. previously detected breast cancer 2. reflexes. lactation. when combined with effects on motility. EEG Interventions: 1. which. fluid overload. anxiety NURSING CONSIDERATIONS Assessment: 1.

.Prophylaxis of postoperative nausea and vomiting when nasogastric suction is undesirable. has sedative properties. increases lower esophageal sphincter pressure. and intestinal transit. induces release of prolactin alterations in timing of food absorption. little effect on gallbladder or colon motility.

tinnitus. monitor accordingly. 2. allergies. History: renal impairment. aspirin allergy. renal toxicity. peripheral sensation. somnolence. inhibits prostaglandin s and leukotriene synthesis CNS: headache. Physical: skin color and lesions. orientation. pregnancy 2. impaired hearing. Be aware that patient may be at risk for CV events. Do not use during . dizziness. during labor and delivery. recent GI bleed or perforation Use cautiously with impaired hearing. lactation. CONTRAINDICATION S Contraindicated with significant renal impairment. hepatic conditions ACTION SIDE EFFECT Generic Name: Ketorolac Tromethamin e Brand Name: Toradol Class: Antipyretic NSAID Antiinflammatory and analgesic activity.DRUG DOS E 1 AMP q6 hrs and PRN for pain ROUT E IV INDICATION S Short-term management of pain (up to 5 days) Ophthalmic: relief of ocular itching due to seasonal conjunctivitis and relief of post-operative inflammation after cataract surgery. insomnia. CBC. ophthalmologi c effects NURSING CONSIDERATION S Assessment: 1. dizziness. hepatic. GI bleeding. clotting times. adventitious sounds Interventions: 1. lactation. fatigue. allergies. reflexes.

labor. or while nursing. in case of severe hypersensitivity reaction. 3. Keep emergency equipment readily available at time of initial dose. Administer every 6 hrs to maintain serum levels and control pain. delivery. Protect drug vials from light. 5. . 4.

paresthesias. the gastric alopecia. Physical: skin inhibition of lesions. secretion by pregnancy. dream abnormalities . anxiety. reflexes. 1. History inhibitor: :hypersensitivity to suppresses omeprazole or any of gastric acid its components. Use cautiously with pregnancy. the inflammation. if ACTION SIDE EFFECT CNS.DRUG Generic Name: Omeprazole Brand Name: Tansinel Class: Antisecretory drug DOSE ROUTE INDICATIONS CONTRAINDICATIONS 20 mg 1 cap for two weeks Oral Short-term treatment of active duodenal cancer Short-term treatment of active benign gastric ulcer Eradication of Helicobacter Pylori First-line therapy for treatment of heartburn or symptoms of Contraindicated with hypersensitivity to omeprazole or its components. Interventions: secretory urticaria. hydrogenabdominal potassium examination. lactation specific 2. dizziness. meals. asthenia. apathy. headache. dry 2. Administer parietal skin antacids with. lactation. NURSING CONSIDERATIONS Gastric-acid Assessment: pump 1. Administer before surface of pruritus. insomnia. the urinary output. vertigo. ATPase respiratory enzyme Dermatologic: auscultation system at rash.

tongue atrophy Respiratory: URI symptoms. fever. . vomiting. Have regular medical follow-up visits. dry mouth. 3. cells.GERD. abdominal pain. epistaxis needed. constipation. worsening of symptoms. GI: diarrhea. blocks the final step of acid production. 4. Report severe headache. nausea. cough. chills.

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