130 Research papers supporting Vaccine/Autism CausationGinger Taylor, MS

Mainstream research has found that vaccines and their ingredients can cause the underlying medical conditions that committed physicians and researchers are commonly finding in children who have been given an autism diagnosis. These conditions include gastrointestinal damage, immune system impairment, chronic infections, mitochondrial disorders, autoimmune conditions, neurological regression, glial cell activation, brain inflammation, damage to the blood–brain barrier, seizures, synaptic dysfunction, dendritic cell dysfunction, mercury poisoning, aluminum toxicity, gene activation and alteration, glutathione depletion, impaired methylation, oxidative stress, impaired thioredoxin regulation, mineral deficiencies, impairment of the opioid system, endocrine dysfunction, cellular apoptosis, and other disorders.

1.

Increased risk of developmental neurologic impairment after high exposure to thimerosalcontaining vaccine in first month of life. !ivision of "pidemiology and #urveillance, $accine #afety and !evelopment %ranch, &ational Immunization 'rogram, (enters for !isease (ontrol and 'revention. )***. Thomas M. $erstraeten, +. !avies, !. u, - !e#tefano %ackground (oncern has risen on the presence of the ethylmercury containing preservative thimerosal in vaccines. /e assessed the risk for neurologic and renal impairment associated with past exposure to thimerosalcontaining vaccine using automated data from the $accine #afety !ata link 0$#!1. $#! is a large linked database from four health maintenance organizations in /ashington, 2regon and (alifornia, containing immunization, medical visit and demographic data on over 344,444 infants born between 5*) and 5*6. Methods /e categorized the cumulative ethylmercury exposure from Thimerosalcontaining vaccines after one month of life and assessed the subse7uent risk of degenerative and developmental neurologic disorders and renal disorders beforethe age of six. /e applied proportional hazard models ad8usting for 9M2, year of birth, and gender, excluding premature babies.+esults /e identified :;< children with degenerative and =64: with developmental neurologic disorders, and =)4 with renal disorders. The relative risk 0++1 of developing a neurologic development disorder was ).; 0 *>? confidence intervals @(IA B).):.;1 when comparing the highest exposure group at ) month of age 0cumulative doseC :> ug1 to the unexposed group.

Within thisgroup e also !oun" an ele#ate" ris$ !or the !olloing "isor"ers% autism &RR '(), *+ Cl - 1(.31(+

, non organic sleep disorders 0++ >.4, *>? (l B ).<)>.*D, and speech disorders 0++ :.), *>? 0)B).)3.41. -or the neurologic degenerative and renal disorders group we found no significantly increased risk or a decreased risk. (onclusion

This analysis suggests that high eposure to ethyl mercury !rom thimerosalcontaining #accines in the !irst month o! li!e increases the ris$ o! su2seuent "e#elopment o! neurologic "e#elopment impairment

,

 

but not of neurologic degenerative or renal impairment. -urther confirmatory studies are needed.

2.

9epatitis % vaccination of male neonates and autism diagnosis, &9I# )**6

 

:44:.allagher (M, oodman M#.E Toxicol "nviron 9ealth F. :4)4G6=0:31)<<>66. doi )4.)4;4H)>:;6=*3.:4)4.>)*=)6. Fbstractniversal hepatitis % vaccination was recommended for .#. newborns in )**)G however, safety findings are mixed. The association between hepatitis % vaccination of male neonates and parental report of autism diagnosis was determined. This crosssectional study used weighted probability samples obtained from &ational 9ealth Interview #urvey )**6:44: data sets. $accinationstatus was determined from the vaccination record. Jogistic regression was usedto estimate the odds for autism diagnosis associated with neonatal hepatitis % vaccination among boys age =)6 years, born before )***, ad8usted for race, maternal education, and twoparent household.

4oys #accinate" as neonates ha" three!ol" greater o""s !or autism "iagnosis compare" to 2oys ne#er #accinate" or #accinate" a!ter the !irst month o! li!e(

 &on9ispanic white boys were <3? less likely to have autism diagnosis relative to nonwhite boys. -indings suggest that .#. male neonates vaccinated with the hepatitis % vaccineprior to )*** 0from vaccination record1 had a threefold higher risk for parental report of autism diagnosis compared to boys not vaccinated as neonates during that same time period. &onwhite boys bore a greater risk.

3.

enderselective toxicity of thimerosal.

 

"xp Toxicol 'athol. :44* MarG<)0:1)==<. doi )4.)4)<H8.etp.:44;.46.44:. "pub :44; #ep =.!epartments of Medicine and Jaboratory Medicine and 'athobiology, niversity of Toronto, 2ntario, (anada. don.branchKutoronto.ca Fbstract F recent report shows a correlation of the historical use of thimerosal in therapeutic immunizations with the subse7uent development of autismG however, this association remains controversial. Futism occurs approximately four times more fre7uently in males compared to femalesG thus, studies of thimerosal toxicity should take into consideration genderselective effects. The present studywas originally undertaken to determine the maximum tolerated dose 0MT!1 of thimersosal in male and female (!) mice. 9owever, during the limited MT! studies, it became apparent that thimerosal has a differential MT! that depends

 

on whether the mouse is male or female.

At "oses o! 3.(5')(.mg/$g using 10 6MS7 as "iluent, se#en o! se#en male mice compare" to 8ero o! se#en !emale mice teste" succum2e" to thimerosal(

 Flthough the thimerosal levels used were very high, as we were originally only trying to determine MT!, itwas completely unexpected to observe a difference of the MT! between male and female mice. Thus, our studies, although not directly addressing the controversy surrounding thimerosal and autism, and still preliminary due to small numbers of mice examined, provide, nevertheless, the first report of genderselective toxicity of thimerosal and indicate that any future studies of thimerosal toxicity should take into consideration genderspecific differences.

4.

Mercury toxicokineticsdependency on strain and gender.

 

Toxicol Fppl 'harmacol. :4)4 Mar )>G:3=0=1:;=*). doi )4.)4)<H8.taap.:44*.4;.4:<. "pub :44* #ep :."kstrand E), &ielsen E%, 9avarinasab #, Lalups +, #Nderkvist ', 9ultman '.Molecular and Immunological 'athology, !epartment of (linical and "xperimental Medicine, JinkNping niversity, #weden. FbstractMercury 09g1 exposure from dental amalgam fillings and thimerosal in vaccines is not a ma8or health hazard, but adverse health effects cannot be ruled out in a small and more susceptible part of the exposed population. Individual differencesin toxicokinetics may explain susceptibility to mercury. Inbred, 9:congenic  F.#/ and %)4.# mice and their -) and -:hybrids were given 9g(l: with :.4 mg 9gHJ drinking water and traces of 0:4=19g. /holebody retention 0/%+1 was monitored until steady state after > weeks, when the organ 9g content was assessed. !espite similar 9g intake,

A(SW males attaine" a 9030 signi!icantly higher W4R an" 9 to +!ol" higher total renal :g retention/concentration than A(SW !emales an" 410(S mice( A selecti#e renal :g accumulation 2ut o! loer magnitu"e as seen also in 410(S males compare" ith !emales(

 !ifferences in /%+ and organ 9g accumulationare therefore regulated by non9: genes and gender. Jymph nodes lacked the strain and genderdependent 9g accumulation profile of kidney, liver and spleen. Ffter )> days without 9g F.#/ mice showed a 3fold higher /%+ and liver 9g concentration, but ))fold higher renal 9g concentration, showing the key role for the kidneys in explaining the slower 9g elimination in F.#/ mice. The trait causing higher mercury accumulation was not dominantly inherited in the -) hybrids. -: mice showed a large interindividual variation in 9g accumulation, showing that multiple genetic factors influence the 9g toxicokinetics in the mouse. The genetically heterogeneous human population may therefore show a large variation in mercury toxicokinetics.

5.

 F +eview of the !ifferences in !evelopmental, 'sychiatric, and Medical "ndophenotypes %etween Males and -emales with Futism #pectrum !isorder