Prepared by: Jade Kenneth Lomansoc

‡ ‡ ‡ ‡

Composed exclusively of chondrocytes Avascular Key tissue in growing bones Well adapted to serve in a weight-bearing capacity (especially at points of movement)

‡ Arises from mesenchyme
± exception of some of the cartilage in head, which is derived from ectomesenchyme by way of neural crest cells

‡ Blastema
± rounded mass of mesenchymal cells with relatively little intercellular material ± Precartilage cells

‡ In close apposition, begin to produce cartilage matrix, referred to as chondrocytes

‡ Progressively move apart and continually deposit matrix

‡ Completely surrounded by matrix material called perichondium

‡ (The ability of damaged cartilage to repair itself is limited)
± Appositional
‡ Formation of cartilage onto the surface of pre-existing cartilage ‡ Derived from the perichondrium

± Interstitial
‡ Within the cartilage mass ‡ Possible because chondrocytes are still capable of cell division and because the matrix is distensible

‡ Hyaline ‡ Elastic ‡ Fibrocartilage

Intial skeleton of the fetus Precursor of bones via endochondral ossification Serves as the epiphyseal growth plate Articular bone surface (adult long bone) Generally surrounded by perichondrium -> dense connective tissue (capsule) -> inner (cartilage cells) and outer (fibrous) ‡ Trachea, bronchi, larynx, nose, and the costal cartilages (ends of ribs) ‡ ‡ ‡ ‡ ‡

‡ Calcification
± First, that portion of articular cartilage that is in contact with the bone is calcified ± Second, calcification always occurs in cartilage that is about to be replaced by bone during the growth period of the individual ± Third, hyaline cartilage throughout the body calcifies as part of the aging process

‡ Matrix contains elastic fibers and sheets of elastic materials in addition to collagen fibrils and ground substance ‡ Does not calcify ‡ (+) perichondrium ‡ External ear, walls of external auditory canal and auditory (eustachian) tube, in the larynx

‡ Matrix contains obvious bundles of thick collagen fibers (mostly type I) ‡ (+) fibrocartilage indicates that resistance to both compression and shear are required of the tissue ‡ Intervertebral discs, symphysis pubis, articular discs of the sternoclavicular and temporomandibular joints, the menisci of the knee joints, and certain places where tendons attach to bones

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