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Tryptophan

Tyrosin
e

L-Dopa
5-HT

Dopamine

Serotonin

Norepinephrine

Selective Serotonin reuptake Inhibitors SSRIs

Selective Norepinephrine Reuptake Inhibitors NRIs
Selective Serotonin Norepinephrine Reuptake
Inhibitors SNRIs
Dopamin-Norepinephrine Reuptake Inhibitors DNRIs
Inhibitors of MAO MAOI
Tricyclic & Tetracyclic antidepressant drugs- TCA
Atypical antidepressive drugs

Selective Serotonin
Reuptake Inhibitors SSRIs
Generic name
Brand name
Day. dose
Fluoxetine

Prozac
Flutine
Prizma

PO

20-60 mg

Fluvoxamine

Favoxil

PO

50-250 mg

Paroxetine

Paxxet
Seroxat

PO

20-60 mg

Sertraline

Lustral

PO

50-200 mg

Citalopram

Cipramil

PO

20-60 mg

Escitalopram

Cipralex

PO

10-30 mg

 SSRIs
\

"

Serotonin discontinuation
syndrome
SIADH

 SSRIs
.
-
.
- ,,
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.

.
)(Friedman, 2009

Selective Norepinephrine
Reuptake Inhibitors NRIs
Generic name

Brand name

Reboxetine

Edronax

Day. dose
PO

4-16 mg

Selective Serotonin Norepinephrine

Reuptake Inhibitors- SNRIs
Generic name

Brand name

Day. dose

Venlafaxine
(also XR)

Efexor,
Viepax

PO

150-300 mg

Duloxetine

Cymbalta

PO

60-90 mg

Milnacipran

Ixel

PO

50-25 mg

: SSRIs : .
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Dopamin-Norepinephrine
Reuptake Inhibitors DNRIs
Generic
name

Brand name

Bupropion

Zyban

Day. dose
PO

150-450mg

SSRIs

.

Inhibitors of MAO -MAOI

Generic name

Brand name

Tab size

Meclobemide

Mobemide

PO

150mg

Phenelzine

Nardil

PO

15mg

Selegiline

Selegiline

PO

5mg

Day. dose

Tricyclic & Tetracyclic

antidepressant drugs -TCA
Generic name

Brand name

Day. dose

Tertiary Tricyclics
Imipramine

Primonil, Tofranil

PO

150-300mg

Amitriptyline

Elatrol, Tryptal
Elatrolet

PO

150-300mg

Clomipramine
SR

Anafranil, Maronil

PO

150-300mg

Desipramine

Deprexan

PO

75-300mg

Nortriptyline

Nortyllin

PO

50-150mg

Maprotiline

Ludiomil, Melodil

PO

100-225mg

Mianserin

Bonserin

PO

30-60mg

Secondary Tricyclics

Tetracyclics

 TCA

:

CNS : .

1-

H1

Atypical antidepressive drugs

Generic name

Brand name

Day. dose

Mirtazapine

Remeron

PO

30-60 mg

Trazodone

Trazodil,
Depyrel

PO

100-300 mg

Nefazodone

Serzonil

PO


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.

 -
Lithium

Anti-epileptic drugs

Lithium
Generic name

Brand name

Lithium

Licarbium

Day. dose
PO

150-1500mg

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Anti-epileptic drugs
Generic name

Brand name

Day. dose

4-12 mcg\ml

mood stabilizer
Carbamazepine *

Tegretol , Teril
\CR
Timonil

PO

600-1200 mg

Valproic acid *
(Valproate)

Valporal,
Depalept

PO

1200-1500 mg 50-100 mg\ml

Lamotrigine

Lamictal

PO

200-400 mg

Topamax

PO

200-400 mg

other indications
Topiramate


Anti-epileptic drugs
Carbamazepine:Valproic acid -

.
SIADH

CNS
:Lamotrigine

CNS

Topamax

CNS .

SJS

 -
- :
, .
).(Brief psychotic episode

) psychotic
.(features
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''

Typical antipsychotics
Generic name

Brand name

Day Dose

Typical antipsychotics, high potency

Haloperidol

Haldol, Peridor

PO, IV,IM

4-10 mg

Fluphenazine

Sediten

PO

1-20 mg

Fluphenazine

Modecate

IM

25-50 Mg / ml

Perphenazine

Perphenan

PO

8-40 mg

Zuclepenthixol

Clopixol
Clopixol acuphase
Clopixol depot

PO
IM
IM

5-50 mg
50/100 mg / 72 hours
200 /month

Typical antipsychotics
Typical antipsychotics, low potency
Chlorpromazine

Taroctyl

PO

300-500mg

Thioridazine

Melleril ,
Ridazin

PO

200-600 mg

Typical antipsychotics, others

Clotiapine

Entumine

PO

20-160 mg

Sulpiride

Modal

PO

50-200 mg

Sulpiride

Modal forte

PO

200 mg

Penfluridol

Semap

PO

20 mg / week

Levomepromazine

Nozinan

PO

200-400 mg

Typical antipsychotics

Extra Pyramidal Syndrome :

Acute dystonia

Tardive dyskinesia

Orthostatic Hypotension :

:M1
, :H1

Typical antipsychotics

NMS

Neuroleptic Malignant
Syndrome :NMS

.

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, ,

CPK :
.
: , ," ,
.
: , , .

Atypical antipsychotics
Generic name

Brand name

Day Dose

Clozapine

Leponex

PO

400-600 mg

Quetiapine

Seroquel

PO

400-700 mg

Risperidone

Risperdal
Risperdal consta
Risperdal quicklet

PO
IM
PO

2-10 mg
50 mg
2 mg

Olanzapine

Zyprexa
Zyprexa
Zyprexa velotabs

PO
IM
PO

5-20 mg
20 mg

Ziprasidone

Geodon

PO
IM

120-160 mg
20 mg

Amisulpride

Solian

PO

50-200 mg

Aripiprazole

Abilify

PO

15 mg

Atypical antipsychotics

" .
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)(Ziprasidone, Risperidone
) :(clozapine
) (Ziprasidone QT

 -
:
:

acute dystonia

-
Generic name

Brand name

Daily
Dose

Biperiden

Dekinet

PO

2-6 mg

Trihexyphenidyl

Artane

PO

2.5-15 mg

 /
:
.generalized anxiety disorder *
.panic disorder *
.social phobia *
.obsessive compulsive disorder *
.post-traumatic stress disorder *
.*
akathisia , ,
.

 /
Generic name

Brand name

Tab size

Benzodiazepine agonists, long half-life

Chlordiazepoxid Librium
e

PO

Diazepam

Assival , Valium

PO\ IV

2 / 5 / 10 mg

Clonazepam

Clonex

PO

0.5 / 2mg

Nitrazepam

Numbon

PO

5 mg

Flunitrazepam

Hypnodorm

PO

2 mg

Benzodiazepine agonists, intermediate half-life

Lorazepam

Lorivan

PO

1 mg

Alprazolam

Xanagis,
Alpralid,
Alprox,
Apox
Xanax XR

PO

0.25 / 0.5 / 1/ 2 mg

Oxazepam

Vaben

PO

10/ 30 mg

Brotizolam

Bondormin

PO

0.25 mg

Benzodiazepine agonists, short half-life

Midazolam

Dormicum

PO

Clorazepate
(nordazepam)

Tranxal

PO

5 / 15 mg

Benzodiazepine agonists, other

Zolpidem

Stilnox, Zoton

PO

10mg

Zolpiclone

Nocturno,
Imovane

PO

7.5 mg

Generic name

Brand name

Tab size

Benzodiazepine antagonists
Flumazenil

Anexate

IV

0.1 Mg / ml

 /
Generic name

Brand name

Tab size

5HT1A agonists
Buspirone

Sorbon ,
buspirol

PO

Phenergan

PO

25 mg

Deralin

PO

10 mg

Anti Histamine
promethazine
Blockers
Propranolol


:
attention-deficit / hyperactivity ) ADHD
.(disorder
.Narcolepsy
.


Generic name

Brand name

Tab size

Day. dose

Methylphenidate

Ritalin

PO

5-60 mg

Methylphenidate
sustained-release

Ritalin SR

PO

5-60 mg

Methylphenidate
extended-release

Concerta

PO

18-54 mg

 '
major depressive disorder
'

SSRI

II

T3
NRI

SNRI

Atypical

T3
NRI
ECT

Atypical

 '
major depressive disorder
Acute phase

Partial response

Complete remission
Continuation phase

Relapse
Reaccurance
Recovery / Maintenance


Acute phase
Relapse

Relapse

Stabilization phase

Chronic / Stable phase

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