Generic name, Brand name, Dosage Cefuroxime axetil Ceftin Dosages: Oral Adults and patients 12 yr and older

250 mg bid. For severe infections may be increased to 500mg bid. Treat up to 10 days. Pediatric patients younger than 12 yr 125 mg bid




Side effects

Nursing responsibilities Assessment • History: Hepatic and renal impairment, lactation, pregnancy • Physical: Skin status, LFTs, renal function tests, culture of affected area, sensitivity tests Interventions • Culture infection, and arrange for sensitivity tests before and during therapy if expected response is not seen • Give oral drug with food to decrease GI upset and enhance absorption • Give oral drug to children who can swallow tablets; crushing the drug results in a bitter, unpleasant taste

Antibiotic Cephalosporin

Tablets – 125, 250, 500mg; suspension – 125 mg/5mL; powder for injection – 750 mg, 1.5g; injection – 750 mg, 1.5 g

Oral: • Pharyngitis, tonsillitis caused by Streptococcus pyogenes • Otitis media caused by Streptococcus pneumonia, S.pyogenes, Haemophilus influenza, Moraxella catarrhalis • Lower respiratory infections caused by S.pneumoniae, Haemophilus parainfluenzae, H.influenzae • UTI’s caused by E.coli, Klebsiella pneumonia • Uncomplicated gonorrhea • Skin and skin structure infections, including impetigo caused by Streptococcus aureus, S.pyrogenes • Treatment of early Lyme disesase

GI: stomach upset, diarrhea, loss of appetite, nausea or vomiting. headache, dizziness, fatigue, muscle aches, strange taste in the mouth, persistent fever, easy bruising or bleeding, persistent sore throat

Have vitamin K available in case hypoprothrombi nemia occurs Discontinue if hypersensitivity reaction occurs

Teaching points Oral drug • Take full course of therapy even if you are feeling better • This drug is specific for this infection and should not be used to self-treat other problems • Swallow tablets whole; do not crush them. Take the drug with food. • You may experience these side effects: stomach upset or diarrhea • Report severe diarrhea with blood, pus, or mucus; rash; difficulty of breathing; unusual tiredness, fatigue; unusual bleeding or

bruising; unusual itching or irritation.

Aluminum hydroxide Maalox


Tablets – 300, 500, 600 mg; capsules – 400, 500mg; suspension – 320 mg/5mL, 450mg/5mL, 675mg/5mL; liquid – 600 mg/5mL

• •

Dosages: Adults 500 – 1500 mg 3-6 times/day PO between meals and at bedtime

Symptomatic relief of upset stomach associated with hyperacidity Hyperacidity associated with peptic ulcer, gastritis, peptic esophagitis, gastric hyperacidity, hiatal hernia Unlabeled uses: Prophylaxis of GI bleeding, stress ulcer; reduction of phosphate absorption in hyperphosphatemia in patients with chronic renal failure

GI: constipation; Assessment intestinal • History: allergy obstruction, to aluminum decreased products; gastric absorption of outlet fluoride, obstruction; accumulation of hypertension, aluminum in heart failure, serum, bone, and hypophosphatem CNS ia, lactation Musculoskeletal:o • Physical: bone steomalacia and strength, muscle chronic phosphate strength; deficiency with auscultation, BP, bone pain, malaise, peripheral muscular weakness edema; abdominal examination, bowel sounds; serum phosphorus, serum fluoride; bone X-ray is appropriate Interventions • Give hourly for first 2wk when used for acute peptic ulcer; during the healing stage, give 1-3 hr after meals and at

bedtime ○ Warning: do not administe r oral drugs within 12 hr antacid administr ation Have patient chew tablets thoroughly; follow with a glass of water Monitor serum phosphorus levels periodically during long-term therapy.

Teaching points • Take this drug between meals and at bedtime • Do not take maximum dosage of antacids for longer than 2 weeks except under medical supervision • Do not take this drug with any other oral medications; absorption of

• •

those medications can be inhibited. Take oral medications at least 1-2 hours after aluminum salt Constipation may occur Report constipation; bone pain, muscle weakness; coffee ground vomitus, black tarry stools, no relief from symptoms being treated

Essentiale Forte Dosages: Essentiale cap Maintenance therapy 1-2 cap tid. Essentiale Forte cap Intensive therapy 1-2 cap tid for the 1st 2 mth.

Hepatic protectors

ESSENTIAL E- solution for intraveno us injections in vials 5 ml. ESSENTIAL E FORTE N- Capsules N30 or N100. ESSENTIAL E N. -solution for intravenous injection in vials 5 ml. ESSENTIAL E FORTE –

Acute, subacute & chronic hepatitis; toxic metabolic liver diseases, intoxications (eg from drugs); infection, fatty degeneration of the liver due to alcohol, hypernutrition, DM, kwashiorkor, pregnancy; cholestasis; pre- & post-op care, esp in liver/gallbladder surgery

abdominal pain, nausea, diarrhea and allergic reaction(skin rash)

Do not use Essentiale in hypersensitivity or all ergy to any ingredients of the preparation. The application of Essentiale in newborn children is not safe. During pregnancy women are recommended to consult their health care provider prior to taking Essentiale.

capsules N50. Essentiale forte contains essential phospholipid s(EPL substance) 300 mg, Thiamine mono nitrate(Vitam in B1)6 mg, Riboflavine( Vitamiin B2) 6 mg, Pyridoxine chidrochlorid e 6mg(Vitamin B6), Cyanocobola mine 0.06 mg (Vitamin B12), Nicotinamid e 30mg, Tocopherole acetate 6 mg(Vitamin E). Omeprazole Risek Dosages: • Cap Duode Antacids, Antireflux Agents Antiulcerants DR capsules – 10, 20, 40 mg; DR tablets – 20mg (OTC); powder for oral suspension – 20, 40 mg/packet • • • Short-term treatment of active duodenal ulcer First-line therapy in treatment of heartburn or symptoms of GERD Short-term treatment of Some of the most frequent side effects of omeprazole (experienced by over 1% of those Assessment: • History: hypersensitivity to omeprazole or any of its components;

nal ulcer 20 mg once daily for 24 wk. Gastric ulcer & reflux esophagiti s 20 mg once daily w/ amoxicillin 1.5-3 g daily in divided doses for 2 wk. ZollingerEllison syndrome 60 mg once daily. Doses >80 mg should be divided & administere d bid. Vial GER D, peptic ulcer disease, NSAIDassociated ulcer 40 mg IV once daily. ZollingerEllison

active benign gastric ulcer GERD, severe erosive esophagitis, poorly responsive symptomatic GERD Long-term therapy: treatment of pathologic hypersecretory conditions (Zollinger-Ellison’s syndrome, multiple adenomas, systemic mastocytosis) Eradication of Helicobacter pylori with amoxicillin or metronidazole and clarithromycin Unlabeled use: posterior laryngitis; enhance efficacy of pancreatinin for the treatment of steatorrhea in cystic fibrosis.

taking the drug) are headache, diarr hea, abdominal pain,nausea, dizzin ess, trouble awakening and sleep deprivation, although in clinical trials the incidence of these effects with omeprazole was mostly comparable to that found with placebo. Proton pump inhibitors may be associated with a greater risk of hip fractures, and clost ridium difficileassociated diarrhea. Patients are frequently administered the drugs in intensive care as a protective measure against ulcers, but this use is also associated with a 30% increase in occurrence of pneumonia.

pregnancy, lactation Physical: skin lesions; T; reflexes, affect, urinary output, abdominal examination; respiratory auscultation

Intervention • Administer before meals. Caution patient to swallow capsules whole – not to open, chew, or crush them. If using oral suspension, empty packet into a small cup containing 2 tbsp of water. Stir and have patient drink immediately; fill cup with water and have patient drink this water. Do not use other diluents. Teaching points • Take drug before meals. • Have regular medical followup visits

syndrome Initially 60 mg IV daily & dose adjusted individuall y. Dose >60 mg given bid. Prophylax is of acid aspiration 40 mg IV completed 1 hr preop. Eradicatio n of H. pylori 40 mg daily combined w/ antibacteria ls in dual therapy or omeprazole 20 mg bid w/ antibacteria ls in triple therapy.

Report severe headache, worsening of symptoms, fever, chills

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