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On the other hand, the slowly progressive amelioration consequent
on a very minute dose, whose selection has been accurately
homoeopathic, when it has met with no hindrance to the duration of
its action, sometimes accomplishes all the good the remedy in
question is capable from its nature of performing in a given case, in
periods of forty, fifty or a hundred days. This is, however, but rarely
the case; and besides, it must be a matter of great importance to the
physician as well as to the patient that were it possible, this period
should be diminished to one-half, one-quarter, and even still less, so
that a much more rapid cure might be obtained. And this may be
very happily affected, as recent and oft-repeated observations have
shown, under three conditions: firstly, if the medicine selected with
the utmost care was perfectly homoeopathic; secondly, if it was
given in the minutest dose, so as to produce the least possible
excitation of the vital force, and yet sufficient to effect the necessary
change in it; and thirdly, if this minutest yet powerful dose of the
best selected medicine be repeated at suitable intervals, 1 which
experience shall have pronounced to be the best adapted for
accelerating the cure to the utmost extent, yet without the vital force,
which it is sought to influence to the production of a similar
medicinal disease, being able to feel itself excited and roused to
adverse reactions.

1 In the former editions of the Organon I have advised that a single dose of a
well-selected homoeopathic medicine should always be allowed first fully to
expend its action before a new medicine is given or the same one repeated - a
doctrine which was the result of the positive experience that neither by a larger
dose of the remedy, which may have been well chosen (as has been again
recently proposed, but which would be very like a retrograde movement), nor,
what amounts to the same thing, by several doses of it given in quick succession,
can the greatest possible good be effected in the treatment of diseases, more
especially of chronic ones; and the reason of this is, that by such a procedure the
vital force dose not quietly adapt itself to the transition from the natural disease
to the similar medicinal disease, but is usually so violently excited and disturbed


by a larger dose, or by smaller doses of even a homoeopathically chosen remedy
given rapidly one after the other, that in most cases its reaction will be anything
but salutary and will do more harm than good. As long as no more efficacious
mode of proceeding than that then taught by me was discovered, the safe
philanthropic maxim of sin non juvat, modo ne noceat, rendered it imperative
for the homoeopathic practitioner, for whom the weal of his fellow-creatures
was the highest object, to allow, as a general rule in diseases, but a single dose at
a time, and that the very smallest, of the carefully selected remedy to act upon
the patient and, moreover, to exhaust its action. The very smallest, I repeat, for it
holds good and will continue to hold good as a homoeopathic therapeutic maxim
not to be refuted by any experience in the world, that the best doses of the
properly selected remedy is always the very smallest on in one of the high
potencies (X), as well for chronic as for acute as for acute diseases - a truth that
is the inestimable property of pure homoeopathy and which as long as allopathy
and the new mongrel sect, whose treatment is a mixture of allopathic and
homoeopathic processes is not much better continues to gnaw like a cancer at
the life of sick human beings, and to ruin them by large and ever larger doses of
drugs, will keep pure homoeopathy separated from these spurious arts as by an
impassable gulf.

On the other hand, however, practice shows us that though a single one of these
small doses may suffice to accomplish almost all that it was possible for this
medicine to do under the circumstances, in some, and especially in slight cases
of disease, particularly in those of young children and very delicate and
excitable adults, yet that in many, indeed in most cases, not only of very chronic
diseases that have already made great progress and have frequently been
aggravated by a previous employment of inappropriate medicines, but also of
serious acute diseases, one such smallest dose of medicine in our highly
potentized dynamization is evidently insufficient to effect all the curative action
that might be expected from that medicine, for it may unquestionably be
requisite to administer several of them, in order that the vital force may be
pathogenetically altered by them to such a degree and its salutary reaction
stimulated to such a height, as to enable it to completely extinguish, by its
reaction, the whole of that portion of the original disease that it lay in the power
of the well-selected homoeopathic remedy to eradicate; the best chosen medicine
in such a small dose, given but once, might certainly be of some service, but
would not be nearly sufficient.

But the careful homoeopathic physician would not venture soon to repeat the
same dose of the same remedy again, as from such a practice he has frequently
experienced no advantage, but most frequently, on close observation, decided
disadvantage. He generally witnessed aggravation, from even the smallest dose
of the most suitable remedy, which he has given one day, when he repeated the
next day and the next.

Now, in cases where he was convinced of the correctness of his choice of the
homoeopathic medicine, in order to obtain more benefit for the patient than he
was able to get hitherto from prescribing a single small dose, the idea often
naturally struck him to increase the dose, since, for the reason given above, one
single dose only should be given; an, for instance, in place of giving a single


very minute globule moistened with the medicine in the highest dynamization,
to administer six, seven or eight of them at once, and even a half or a whole
drop. But the result was almost always less favourable than it should have been;
it was often actually unfavourable, often even very bad - an injury that, in a
patient so treated, is difficult to repair.

The difficulty in this case is not solved by giving, instead, lower dynamizations
of the remedy in a large dose.

Thus, increasing the strength of the single doses of the homoeopathic medicine
with the view of effecting the degree of pathogenic excitation of the vital force
necessary to produce satisfactory salutary reaction, fails altogether, as
experience teaches, to accomplish the desired object. This vital force is thereby
too violent and too suddenly assailed and excited to allow it time to exercise a
gradual equable, salutary reaction, to adapt itself to the modification effected in
it; hence it strives to repel, as if it were an enemy, the medicine attacking it in
excessive force, by means of vomiting, diarrhoea, fever, perspiration, and so
forth, and thus in a great measure it diverts and renders nugatory the aim of the
incautious physician - little or no good towards curing the disease will be
thereby accomplished; on the contrary, the patient will be thereby perceptibly
weakened and, for a long time, the administration of even the smallest dose of
the same remedy must not be thought of if we would not wish it to injure the

But it happens, moreover, that a number of the smallest doses given for the same
object in quick succession accumulate in the organism into a kind of excessively
large dose, with (a few cases excepted) similar bad results; in this case the vital
force, not being able to recover itself betwixt every dose, though it be but small,
becomes oppressed and overwhelmed, and thus being incapable of reacting in a
salutary manner, it is necessitated passively to allow involuntary the continuance
of the over-strong medicinal disease that has thus been forced upon it, just in the
same manner as we may every day observe from the allopathic abuse of large
cumulative doses of one and the same medicine, to the lasting injury of the

Now, therefore, in order, whilst avoiding the erroneous method I have here
pointed out, to attain the desired object more certainly than hitherto, and to
administer the medicine selected in such a manner that it must exercise all its
efficacy without injury to the patient, that it may effect all the good it is capable
of performing in a given case of disease, I have lately adopted a particular

I perceived that, in order to discover this true middle path, we must be guided as
well by the nature of the different medicinal substances, as also by the corporeal
constitution of the patient and the magnitude of the disease, so that - to give an
example from the use of sulphur in chronic (psoric) diseases - the smallest dose
of it (tinct, sulph. X°) can seldom be repeated with advantage, seen in the most
robust patients and in fully developed psora, oftener than every seven days, a
period of time which must be proportionally lengthened when we have to treat
weaker and more excitable patients of this kind; in such cases we would do well


to give such a dose only every nine, twelve, or fourteen days, and continue to
repeat the medicine until it ceases to be of service. We thus find (to abide by the
instance of sulphur) that in sporic diseases seldom fewer than four, often
however, six, eight and even ten doses (tinct. sulph. X°) are required to be
successively administered at these intervals for the complete annihilation of the
whole portion of the chronic disease that is eradicated by sulphur - provided
always there had been no previous allopathic abuse of sulphur in the case. Thus
even a (primary) scabious eruption of recent origin, though it may have spread
all over the body, may be perfectly cured, in persons who are not too weakly, by
a dose of tinct sulph. X° given every seven days, in the course of from ten to
twelve weeks (accordingly with ten or twelve such globules), so that it will
seldom be necessary to aid the cure with a few doses of carb. veg. X° (also given
at the rate of one dose per week) without the slightest external treatment besides
frequent changes of linen and good regimen.

When for other serious chronic diseases also we may consider it requisite, as far
as we can calculate, to give eight, nine or ten doses of tinct. sulph. (at X°) it is
yet more expedient in such cases, instead of giving them in uninterrupted
succession, to interpose after every, or every second or third dose, a dose of
another medicine, which in this case is next in point of homoeopathic
suitableness to sulphur (usually hep. sulph.) and to allow this likewise to act for
eight, nine, twelve or fourteen days before again commencing a course of three
doses of sulphur.

But it not infrequently happens that the vital force refuses to permit several
doses of sulphur, even though they may be essential for the cure of the chronic
malady and are given at the intervals mentioned above, to act quietly on itself;
this refusal it reveals by some, though moderate, sulphur symptoms, which it
allows to appear in the patient during the treatment. In such cases it is sometimes
advisable to administer a small dose of nux vom. X°, allowing it to act for eight
or ten days, in order to dispose the system again to allow succeeding doses of
the sulphur to act quietly and effectually upon it. In those cases for which it is
adapted, puls. X° is preferable.

But the vital force shows the greatest resistance to the salutary action upon itself
of the strongly indicated sulphur, and even exhibits manifest aggravation of the
chronic disease, though the sulphur be given in the very smallest dose, though
only a globule of the size of a mustard seed moistened with tinct. sulph X° be
smelt, if the sulphur have formerly (it may be years since) been improperly
given allopathically in large doses. This is one lamentable circumstance that
renders the best medical treatment of chronic disease almost impossible among
the many that the ordinary bungling treatment of chronic diseases by the old
school would leave us nothing to do but to deplore, were there not some mode of
getting over the difficulty.

In such cases we have only to let the patient smell a single time strongly at a
globule the size of a mustard seed moistened with mercur metall. X, and allow
this olfaction to act for about nine days, in order to make the vital force again
disposed to permit the sulphur (at least the olfaction of tinct. sulph. X°) to


exercise a beneficial influence on itself - a discovery for which we are indepted
to Dr. Griesselich, of Carlsruhe.

§ 246 Sixth Edition

Every perceptibly progressive and strikingly increasing amelioration
during treatment is a condition which, as long as it lasts, completely
precludes every repetition of the administration of any medicine
whatsoever, because all the good the medicine taken continues to
effect is now hastening towards its completion. This is not
infrequently the cause in acute diseases, but in more chronic
diseases, on the other hand, a single dose of an appropriately selected
homoeopathic remedy will at times complete even with but slowly
progressive improvement and give the help which such a remedy in
such a case can accomplish naturally within 40, 50, 60, 100 days.
This is, however, but rarely the case; and besides, it must be a matter
of great importance to the physician as well as to the patient that
were it possible, this period should be diminished to one-half, one-
quarter, and even still less, so that a much more rapid cure might be
obtained. And this may be very happily affected, as recent and oft-
repeated observations have taught me under the following
conditions: firstly, if the medicine selected with the utmost care was
perfectly homoeopathic; secondly, if it is highly potentized,
dissolved in water and given in proper small dose that experience has
taught as the most suitable in definite intervals for the quickest
accomplishment of the cure but with the precaution, that the degree
of every dose deviate somewhat from the preceding and following in
order that the vital principle which is to be altered to a similar
medicinal disease be not aroused to untoward reactions and revolt as
is always the case 1 with unmodified and especially rapidly repeated

1 What I said in the fifth edition of the organon, in a long note to this paragraph
in order to prevent these undesirable reactions of the vital energy, was all the
experience I then had justified. But during the last four or five years, however,
all these difficulties are wholly solved by my new altered but perfected method.
The same carefully selected medicine may now be given daily and for months, if
necessary in this way, namely, after the lower degree of potency has been used
for one or two weeks in the treatment of chronic disease, advance is made in the
same way to higher degrees, (beginning according to the new dynamization
method, taught herewith with the use of the lowest degrees).

§ 247 Fifth Edition


Under these conditions, the smallest doses of the best selected
homoeopathic medicine may be repeated with the best, often with
incredible results, at intervals of fourteen, twelve, ten, eight, seven
days, and, where rapidity is requisite, in chronic diseases resembling
cases of acute disease, at still shorter intervals, but in acute diseases
at very much shorter periods - every twenty - four, twelve, eight, four
hours, in the very acutest every hour, up to as often as every five
minutes, - in ever case in proportion to the more or less rapid course
of the diseases and of the action of the medicine employed, as is
more distinctly explained in the last note.

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