:
;
, M.D., Ph.D.(c)
...
1
57
.
:
1.
10 mg :
LDL 110 mg/dl, HDL 34 mg/dl, TG 114 mg/dl
2. ( 4)
3. 20 / 40
:
1. 2, ,
2.
1
:
1.
&
2. S1, S2 ,
3. ,
4.
5. : , ,
6. :
a)
b)
c)
: 152/85 mmHg
: 155/87 mmHg
: 160/90 mmHg (: 1.03, )
1
:
?
1.
2.
3.
<120
<80
120-129
80-84
130-139
85-89
140-159
90-99
160-179
100-109
180
110
140
<90
Mancia G, Fagard R, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial
hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 2013; 34:
2159-2219
140
90
135
85
120
70
130
80
135
85
24
( )
( )
24
:
Mancia G, Fagard R, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial
hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 2013; 34:
2159-2219
1
2 :
HBPM:
: 147.8 / 84.2 mmHg
: 151,3 / 87,1 mmHg
1
(),
()
1-2
(mmHg)
1
2
, 3,
, 4,
/
: , : , : , :
-
Mancia G, Fagard R, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial
hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 2013; 34:
2159-2219
1
2 :
H :
S/R 82 bpm
(+) Sokolow
1
2 :
Triplex :
MV & AV
1
57
, , ,
(),
()
&
&
&
&
1-2
&
&
&
&
3
&
&
&
&
, 3,
, 4,
&
&
&
: , : , : , :
1
:
?
1.
2.
3.
4.
5.
6.
7.
8.
24
/
Triplex &
K+, Na+, , ,
1, 4, 6
1
:
, HDL, LDL,
&
eGFR (MDRDC/G)
(dipstick ,
24, )
.
Mancia G, Fagard R, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial
hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 2013; 34:
2159-2219
1
,
,
:
&
24
holter
Mancia G, Fagard R, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial
hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 2013; 34:
2159-2219
1
(,
, ) -
,
.
Mancia G, Fagard R, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial
hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 2013; 34:
2159-2219
1
,
& 2 :
& HBPM:
: 145.1 / 81.2 mmHg
: 155,3 / 84,1 mmHg
:
0,9 eGFR 88 mL/min
24: 38 gr
AST 24, ALT 35, K+ 4.1, Na+ 138
1
:
?
1.
2.
3.
4.
5.
6.
AMEA ARB
CCB
Thiazide diuretic
B-Blocker
1+2
1+2+3
1
57
,
1
57
,
18
( ' )
& - , &
( )
> 60
< 60
<150 mm Hg
<90 mm Hg
<140 mm Hg
<90 mm Hg
ARB CCB
CCB, .
&
<140 mm Hg
<90 mm Hg
<140 mm Hg
<90 mm Hg
ARB,
. 1
1
57
,
1
57
,
2
45 ,
.
, , ,
,
.
:
1. 2
2. Hashimoto TSH:
1,2
3. SSRI
:
1.
2. Parkinson & Alzheimer
2
:
1.
2. S1, S2 & (102bpm),
3. ,
4.
5.
6. : , ,
7. :
a)
b)
c)
: 182/85 mmHg
: 185/87 mmHg
: 190/90 mmHg (: 0.97, )
2
:
?
1.
2.
3.
4.
,
, (WCH)
, (masked HT)
,
2
:
B 320mg A 5mg
N 5mg.
4
155/90 mmHg.
2
:
?
1.
2.
2
:
B 320mg, A 10mg, HCT 25mg
N 5mg
4
150/80 mmHg bpm 85.
,
,
(110-120 bpm), ,
160 mmHg.
2
:
?
1.
2.
3.
4.
Triplex
Triplex
24
. /
/ .
,
,
,
,
.
(
)
Cushing
,
,
,
,
,
, buffalo
hump
24
CT MRI
,
,,
, .
.
:
,
< 40
(
)
,
,
eGFR
U/S NOK
>
1.5
2 ,
eGFR (
)
Triplex
, spiral
,
per os,
, CT
,
3
80
20 Losartan 50 mg 1X1
(
2 , ).
:
1. 24
2. 98
.
3
:
1.
2. S1, S2 , 75 bpm
3. ,
4.
5.
6. :
a)
b)
c)
: 120/65 mmHg
: 115/60 mmHg
: 130/80 mmHg (: 1.1, )
3
H :
S/R 72 bpm
(-) Sokolow
3
:
?
1.
2.
3
2 :
Triplex :
Triplex :
3
2 :
24: 80mg
o GFR: 59 mL/min
, 80 , LVH,
XNN ,
:
?
1. Losartan ABPM &
HBPM >160mmHg
2. Losartan CCB DU 140150mmHg
3. Losartan 120-140mmHg
, 80 , LVH,
XNN ,
:
?
1. Losartan ABPM
& HBPM >160mmHg
2. Losartan CCB DU 140150mmHg
3. Losartan 120-140mmHg
:
?
1. Losartan ABPM &
HBPM >160mmHg
140-150
:
?
1. Losartan ABPM &
HBPM >160mmHg
140-150
, 80 , LVH,
XNN ,
:
?
1. Losartan ABPM &
HBPM >160mmHg
2. Losartan CCB DU 140150mmHg
3. Losartan 120-140mmHg
:
?
2. Losartan CCB DU 140150mmHg
, 80 , LVH,
XNN ,
:
?
1. Losartan ABPM &
HBPM >160mmHg
2. Losartan CCB DU 140150mmHg
3. Losartan 120140mmHg
:
?
3. Losartan 120-140mmHg
:
?
3. Losartan 120-140mmHg
:
?
3. Losartan 120-140mmHg
:
?
3. Losartan 120-140mmHg
:
?
JNC-8
& ESC
:
;