, &

.

...
..


10

Deaths in millions

8.6

8.0

6
4.0

3.4

3.2
1.8

1.7

1.5

1.7

1.3
0.5

0.4
0

A Cardiovascular diseases
B Cancer
C Injuries
WHO. Global Burden of Disease Estimate 2001.

D Respiratory diseases
E HIV/AIDS
F Diabetes

1:

2:

3:

: ?

100
85%
80

71%
60%

60
37%

40
20
0

17%

1319

2029

3039
()

4049

Data from 262 heart transplant donors.

Sites with intimal thickness 0.05 mm were defined as atherosclerotic.
Tuzcu EM, et al. Circulation. 2001;103:2705-2710.

50

, 120
129
80-84

130139
85-89

140159
90-99

160179
100-109

3
180
110

1-2

3
,,

ESC/EAS Guidelines for the Management of Dyslipidemias, Eur Heart J (2011)

32,1769-1818


1
&
LDL-C 30 %
LDL-C. 1
.
.

2 ,
, > 40 1
-
LDL-C < 70 mg/dl .
: non-HDL-C < 100 mg/dl,
apo-B < 80 mg/dl
2
LDL-C < 100 mg/dl. NonHDL-C < 130 mg/dl & apo-B <100 mg/dl
.

ESC/EAS Guidelines for the Management of Dyslipidemias, Eur Heart J (2011)

32,1769-1818

 : =
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, , ,

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25%

16

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17

18




80140mg/dl .

.

19



..

.

.

.

20



1.
2.

.
1.
(, , )
2. ,
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21


..
1,5-3
.
.

5 1/5
.

22

23


24