IUI

A to Z

TYPICAL PREGNANCY RATE PER CYCLE WITH

VARIOUS TREATMENT OPTIONS
In Infertility
Method

Pregnancy Rate (%)

Intercourse (Timed)

4 (Follicle Monitoring)

IUI

---do----

CC

---do----

CC+IUI

FSH / HMG

7.7

CC / FSH /IUI

9-12

FSH/ HMG/IUI

17 20 %

In vitro fertilization

20 to maximum 30

Effect of Etiology on Success Rate

with IUI
Infertility Etiology

Pregnancy Rate (Maximum)

Unexplained

22.6%

Mild male factor

18.8%

Anovulation

12.4%

Endometriosis

6.5%

Tubal Factor

6.5%

Combined factors

9.7%

Endometriosis,Tubal factor,
severe male factor and
combined factor should proceed
earlier to higher
level ART

Our IUI Experience

(2009- 2011)
N = 369 = 23.57%

(two cycles)

(world over success rate 10 to 15% only)

Idiopathic - 30% - (2 cycles)

PCOD 30% - (r FSH) (2 cycles)

Cervical Factor 20%

Endometriosis 15%

After treatment for TB 15%

Immunological cause TNF (treated ) 5 %

Male Infertility
5 - 20 millions 15%
Less then 5 million Nil
AID 46% (2 cycles)

Success rates according to AGE

(Success rate in 1st 2 cycles)

Less then 30 28 %
Less then 35 22%
35- 39 years - 8 %
40 + Nil

PREREQUISITES

Age < 40 yrs

Spont. / Induced ovulation
One patent FT
>10 million pre wash semen count
>5 million post wash semen count
Easy access to uterine cavity

INTRAUTERINE INSEMINATION (IUI):

Steps
1.Patients selection & workup
2.Ovarian stimulation
3.Semen wash
4.Insemination technique
5.Luteal support

What is the difference between

IUI
&

Artificial Insemination

EJACULATORY FAILURE

Severe hypospadias
Retro grade ejaculation
Paraplegics
Impotence & erectile dysfunction

Super ovulation

V/s
Control Ovarian Hyperstimulation
Stimulation
Monitoring
Follicle growth & release of multiple eggs

How Many Eggs ?

Office visits
4-6

Complication of IUI
Stimulation , Technique & others

- Infection -Rare
- Multiple Pregnancy
- OHSS

Can we have sex in Rx cycle ?

IUI is a simple procedure

Easy
Nurses

IUI Preparation in Doctors office

 37 yrs married to 10 yrs

what should be done ?