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ImpactFactor: 1.710|Ranking: Toxicology64outof87|Public,Environmental&OccupationalHealth(SCI)76outof162

ToxicologyandIndustrialHealth
tih.sagepub.com
PublishedonlinebeforeprintOctober4,2013,doi:10.1177/0748233713500823
ToxicolIndHealthOctober4,20130748233713500823

Antitumorcharacterizationofvarious
fractionsofLaunaeaprocumbens
RahmatAliKhan rahmatgul_81@yahoo.com
UniversityofScienceandTechnology,PakistanQuaidiAzamUniversity,
Pakistan
MuhammadRashidKhan
DepartmentofBiochemistry,FacultyofBiologicalSciences,QuaidiAzam
University,Islamabad,Pakistan
NaseerAliShah
DepartmentofBiochemistry,FacultyofBiologicalSciences,QuaidiAzam
University,Islamabad,Pakistan
SumairaSahreen
BotanicalSciencesDivision,PakistanMuseumofNaturalHistory,Islamabad,
Pakistan
SadafNoorElahi
DepartmentofBiochemistry,FacultyofBiologicalSciences,QuaidiAzam
University,Islamabad,Pakistan

Abstract
The antitumor activity of various six fractions of Launaea procumbens were studied
using the potato disk bioassay technique. Three concentrations (10, 100, and 1000
ppm) of all these six fractions were used for characterization of antitumor activity.
Amongthesefractions,methanolicfractionexhibitedsignificantinhibitionof crown gall
tumors caused by Agrobacterium tumefaciens followed by butanolic fraction. These
results revealed that methanolic and butanolic fractions contain bioactive constituents
responsible for inhibition of tumor. Further purification and characterization are in
progressinourlaboratory.

Source: 2013JournalCitationReports
(ThomsonReuters,2014)