BASA DANTES DE GUZMAN GARCIA LUNA NIEGOS PANGILINAN ROLDAN RACELIS SUPERABLE TORNO VILLADOLID

ƒ AGGREGATION OF

PARTICULATE MATTER CAUSED BY COMBINATION WITH SPECIFIC ANTIBODY

Antigen must be exposed and able to bind with antibody

SENSITIZATION AGGLUTINATION ATTI E FO ATION

ƒ

EACH PARTICLE MUST HAVE MULTIPLE ANTIGENIC SITES

EASY TO CARRY OUT OFTEN USED TO IDENTIFY ANTIGEN AND ANTIBODY QUALITATIVE OR SEMIQUANTITATIVE

It is the physical attachment or the association of an antibody to an antigen

First phase of agglutination Rapid and Reversible

- example: IgM is more efficient to agglutinate than IgG -Prozone phenomenon -Postzone phenomenon -Also referred to as epitope

e

- Mutual blocking of the dissimilar antibodies with the same binding constant directed against the epitope located in close proximity on the cell surface.

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