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Group 3 – BSPharmacy 4A

Other Names:
 White tar
 Naphthalene
 Naphthalin
 Naphthene
Chemical Composition:

Mechanism of Toxicity:
 It can cause gastrointestinal upset, and both may cause CNS
stimulation. In addition, naphthalene may produce hemolysis,
especially in patients with glucose-6-phosphate dehydrogenase (G6PD)
 In addition to repelling or killing insects such as moths, mothballs have
been suggested for use as a stovepipe cleaner, a snake repellent, and
to keep away mice or other pests.
Toxic Effects:
 Acute ingestion usually causes prompt nausea and vomiting. Both
compounds are volatile, and inhalation of vapors may cause eye, nose,
and throat irritation.
Naphthalene. Agitation, lethargy, and seizures may occur with
naphthalene ingestion. Acute hemolysis may occur, especially in
patients with G6PD deficiency. Chronic inhalation has also caused
hemolytic anemia.
Antidote: There is no specific antidote
Prehospital. Administer activated charcoal if available. Do not
inducevomiting, because of the risk of lethargy and seizures. Do not
administer milk, fats, or oils, which may enhance absorption.
Hospital. Administer activated charcoal. Gastric emptying is not necessary
if activated charcoal can be given promptly.

Group 3 – BSPharmacy 4A .