Schematic Diagram of Pathophysiology

Modifiable Factors:
-stress
-fatigue caused
overworking
-strenuous works

Non-Modifiable Factors:
-decreased level of progesterone
-aging pf placenta
-oxytocin release
-prostaglandin cascade
-fetal adrenal maturation
-engagement of the presenting part

Onset of
Labor

Uterine contractions that result

to cervical dilatation

decidua produces prostaglandin

E2 and interleukin-8

increase in
uterine activity

decrease
synthesis of
collagen

increase in
production of
MMP

PRETERM PREMATURE
RUPTURE OF MEMBRANES
wound
Second Stage of Labor
healing
mediate
(cardinal movements of the fetus)
d by the
uterusback
backto
Mother
level of hormones
clotting
Third
Stage
to
prepre-pregnant
back
to normal
systems
back
active
bleeding
factors
Postpartum
episiotomy Birth of
pregnant
of Labor
infant
state
to normal

separation and
expulsion of placenta