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Assignment

Dispense 100ml of calamine lotion BP
Rx
Calamine

15gm

Zinc Oxide

5gm

Bentonite

3gm

Sodium Citrate

0.5gm

Liquefied Phenol (80% w/w) 0.5ml (density:1.055g/ml)
Glycerol

5ml

Water qs.

100ml

1. What can calamine be used for and where could you find out information
about it?
Calamine is used to relieve pain, itching, and discomfort from minor skin
irritations such as poison ivy, poison oak, and poison sumac. It also helps
to dry the oozing and weeping caused by irritation due to these plants.
And, you can find information about it in the BNF or APF.

2. What’s the dosage form of the previous preparation?
Lotion (topical)
3. How many phenol (w/w) is in 0.5ml liquefied phenol?
80% (w/w) = 80 g – 100 g
100/1.05 “density of phenol” = 95.2 ml
80 g

95.2 ml

Xg

0.5 ml

x= 0.42g

4. Justify the use of each compound in the given formula?

helps powder to adhere on the skin. antiseptic Water: Solvent 5. emulsifying agent Phenol: preservative. preservative Glycerol: thickening agent. co-solvent. What would be the most important auxiliary label for the formulation?    For external use only Shake well before use Don't apply to broken skin 6.      Zinc oxide: active ingredient “antiseptic “ Bentonite: suspending agent Sodium citrate: controls flocculation “SAA”. Dispense and council?  Avoid Exposure to sunlight  Do not use/Throw away after 28 days .