Introduction to Biochemistry

Intermolecular Forces

Intermolecular Forces
• Attractions between neighboring
• 3 types:
1) dipole-dipole
2) hydrogen bonding
3) London dispersion forces
(AKA: van der Waals forces)

Dipole-dipole attraction
• Attraction between two polar molecules

Dipole - Dipole

Dipole - Dipole

Hydrogen Bonding
• Strongest attraction
• Between hydrogen and O, N, F
• It is NOT a real bond
– It is a magnetic attraction

• ex) surface tension

Hydrogen Bonding

Hydrogen Bonding in H2O

Surface Tension
ex) bug walking on water

London Dispersion Forces
AKA: “van der Waals Forces”
• A temporary dipole
• Weakest attractive force
• Present in nonpolar molecules

Comparing Dipole-Dipole and
London Dispersion

Vander-Waals Forces
AKA London Dispersion Forces