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Drug Study

Drug Study

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Published by: jho_ on Aug 28, 2010
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08/19/2013

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DRUG Drug name: -telmisartan, hydrochlorothiazide Brand name: -micardis plus Doctor’s order: -40mg 1tab OD

INDICATION -essential hypertension ACTION -blocks the vasoconstrictive and aldosteronesecreting effects of angotensin II by binding angiotensin II to the AT I receptor in many tissue.

CONTRAINDICATION -hypersensitivity to the drug -2 and 3 trimester of pregnancy
nd rd

SIDE EFFECTS -diarrhea -anorexia -loss of appetite -gastric irritation -constipation

NURSING CONSIDERATIONS -special precaution in patients with impaired hepatic and renal impairment -special precaution with volume and/or Na-depleted patients -may impair ability to drive or operate machineries

-lactation

DRUG INDICATION CONTRAINDICATION SIDE EFFECTS NURSING CONSIDERATIONS Drug name: -diltiazem Brand name: -cordazem Doctor’s order: -90mg 1tab BID -angina pectoris ACTION -inhibits calcium ion influx across cell membrane during cardiac depolarization. slows SA/AV node conduction times. -sick-sinus syndrome -nausea -2nd and 3rd AV block -swelling/edema -severe hypotension -pregnancy -arrhythmia -headache -rash -fatigue -monitor v/s especially the BP -should be administered with food or after eating . produces relaxation of coronary arteries. dilates peripheral arteries.

It therefore reduces preload and afterload. 1tab BID INDICATION -angina pectoris ACTION . and stimulates guanylate cyclase causing venous vasodilatation.DRUG Drug name: -nicorandil Brand name: -aprior Doctor’s order: -10mg/tab. and improves coronary blood flow. CONTRAINDICATION SIDE EFFECTS NURSING CONSIDERATIONS -may be taken with or without food -monitor v/s especially the BP -may impair ability to drive or operate machineries -cardiogenic shock -hypotension -left ventricular failure with low filling pressure -lactation -headache -flushing dizziness -n&v -weakness -hypotension .Nicorandil dilates arterioles and large coronary arteries by opening the potassium channels.

-lowers cholesterol and lipoprotein levels CONTRAINDICATION -active liver disease -pregnancy -lactation SIDE EFFECTS -Gi disturbance -headache -myalgia -insomnia -pruritus -muscle cramps NURSING CONSIDERATIONS -avoid intake of alcohol -monitor creatinine phosphokinase and transaminase elevation -history of liver disease -monitor v/s especially the BP -should be administered with food or after eating .DRUG Drug name: -atorvastatin Brand name: -lipitor Doctor’s order: -80mg 1tab HS INDICATION -reduction of elevated total cholesterol & LDL cholesterol ACTION -selectively HMGCoA reductase which converts HMG-CoA to mevalonate. a precursor of sterols.

decrease peripheral vascular resistance of smooth muscle (↓BP) CONTRAINDICATION -low BP -CHF -hypersensitivity -hepatic impairment SIDE EFFECTS -headache -edema -dizziness -flushing -palpitation -fatigue -nausea -abdominal pain NURSING CONSIDERATIONS -monitor v/s especially the BP -should be administered with food or after eating .DRUG Drug name: -amlodipine Brand name: -vasalat Doctor’s order: -5mg 1tab OD INDICATION -hypertension ACTION -inhibits influx of calcium ion across cell membranes to produce relaxation of coronary vascular smooth muscle.

25mg 1tab OD INDICATION -atrial fibrillation ACTION -(+) inotrophic effect more available calcium promotes increase forces to increase cardiac output CONTRAINDICATION -hypersensitivity -intermittent complete heart block -2 nd SIDE EFFECTS -anorexia -GI disturbance -atrial tachycardia -gynecomastia -CNS effect NURSING CONSIDERATIONS -monitor v/s -should be administered with food or after eating -watch out for the adverse reaction of drug heart block .DRUG Drug name: -digoxin Brand name: -lanoxin Doctor’s order: -0.

. the enzyme system located at the secretory surface of gastric parietal cell.DRUG Drug name: -pantoprazole Na Brand name: -pantoloc Doctor’s order: -40mg OD - INDICATION CONTRAINDICATION -hypersensitivity to pantoprazole Na and its components SIDE EFFECTS -abdominal pain -diarrhea -constipation -flatulence -nausea -headache -dizziness -blurred vision -rash -pruritus NURSING CONSIDERATIONS -should be taken on an empty stomach (take 1 hour before meal) ACTION -inhibits both basal & stimulated gastric acid secretion by suppressing the final step in acids production. through inhibition of proton pump by binding to & inhibiting hydrogen potassium adenosine triphosphate.

CONTRAINDICATION -hypersensitivity to montelukast and its component SIDE EFFECTS -abdominal pain -thirst -headache -vomiting NURSING CONSIDERATIONS DRUG INDICATION CONTRAINDICATION SIDE EFFECTS NURSING CONSIDERATIONS . including prevention of day & night time symptoms ACTION .Montelukast is a selective leukotriene receptor antagonist that blocks the effects of cysteinyl leukotrienes in the airways.DRUG Drug name: -montelukast Brand name: -singulair Doctor’s order: -10mg 1tab OD INDICATION -prophylaxis & treatment of asthma.

released from parasympathetic nerve endings. tiotropium bromide competitively and reversibly antagonises the M3- -hypersensitivity to tiotropium Br and its component -dry mouth -constipation -cough & local irritation -tachycardia -urinary retention -do not take more than there recommended dose . It has a similar affinity to the subtypes of muscarinic receptors M1-M5. tiotropium bromide inhibits the cholinergic (bronchoconstrictive ) effects of acetylcholine.Drug name: -tiotropium Br Brand name: -spiriva Doctor’s order: -OD at HS -maintenance treatment for patients with COPD ACTION -By binding to the muscarinic receptors in the bronchial smooth musculature. In the airways.

resulting in relaxation .receptors.

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