Drugs Name Norocaine

Generic Name Procaine

Brand Name Norocaine

Classification Local Anesthetics




Used as a local anesthetic primarily in oral surgery

Acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Norocaine has also been shown to bind or antagonize the function of Nmethyl-Daspartate (NMDA) receptors as well as nicotinic acetylcholine receptors and the serotonin receptor-ion channel complex. .

Side Effect/ Adverse Reaction Respiratory and cardiovascular depression, Hypotension, dysrhythmias, hepatic dysfunction, Nausea, Vomitting, Hypersensitivity

Nursing Consideration _Monitor client’s post postoperative state of sensorium. Report if clients remains unresponsive or confused for a time _Check preoperative and postoperative urine output. Report deficit of hourly or 8-hour urine output _Administer analgesic or narcoticanalgesic with caution until client fully recovers from anesthetic. To prevent adverse reactions, dosage might need to be adjusted if client is under influence of anesthetic. _Monitor Vital signs. Hypotension and respiratory distress may result.

Patient Teachings _Explain to client the preoperative preparation and postoperatve nursing assessment and interventions _Discuss common side effects of local anesthesia to reduce anxiety

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