08B8E1

BIOPHARMACEUTICAL TECHNOLOGY L 3 T 0 P 0 C 3 7

UNIT – I

INTRODUCTION

Pharmaceutical industry & development of drugs ; types of therapeutic agents and their uses ; economics and regulatory aspects . UNIT – II DRUG ACTION, METABOLISM AND PHARMACOKINETICS 9

Mechanism of drug action; physico-chemical principles of drug metabolism; radioactivity; pharmacokinetics. UNIT – III MANUFACTURE OF DRUGS, PROCESS AND APPLICATIONS 7

Types of reaction process and special requirements for bulk drug manufacture of- Aspirin, penicillin, streptomycin. UNIT – IV PRINCIPLES OF DRUG MANUFACTURE 13

Compressed tablets; dry and wet granulation; slugging or direct compression; tablet presses; coating of tablets; capsule preparation; oval liquids – vegetable drugs – topical applications; preservation of drugs; analytical methods and other tests used in drug manufacture; packing techniques; quality management; gmp. UNIT – V BIOPHARMACEUTICALS 9

Various categories of therapeutics like vitamins, laxatives, analgesics, contraceptives, antibiotics, hormones and biologicals: vaccines, monoclonal and polyclonal antibodies, growth hormones, cytokines. . Total : 45 Hours TEXT BOOK 1. Leon Lachman tel al theory and Practice of Industrial Pharmacy, 3 Edition, Lea and Febiger, 1986.

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Remington’s Pharmaceutical Sciences, Mark publishing and Co.

REFERENCES 1. Gareth Thomas. Medicinal Chemistry. An introduction. John Wiley. 2000. Katzung B.G. Basic and Clinical Pharmacology, Prentice Hall of Intl. 1995.

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