is a group of metabolic disease characterized by increased levels of glucose in the blood (HYPERGLYCEMIA) resulting from defects in insulin secretion, insulin action, or both. Normal Range for blood glucose 80-150 mg/dL.

1. Type 1 Diabetes a. Onset any age, but usually young (< 30 years old) b. Usually thin at diagnosis recent weight loss c. Etiology includes genetic, immunologic, and environmental factors. d. Insulin Dependent 2. Type 2 Diabetes a. occurs more commonly among people who are older than 30 years old b. Obese c. Two main problems related to insulin in type 2 diabetes are Insulin resistance and Impaired insulin secretion. Insulin resistance refers to decreased tissue sensitivity to insulin. While, impaired insulin secretion, refers lack of supply of insulin. Signs and Symptoms of Type 2 diabetes 1. 2. 3. 4. 5. 6. 7. Fatigue Irritability’ Polyuria Polydipsia Poorly healing skin wounds Vaginal Infection Blurred Vision

This may indicate that glucose level is very high.

Obesity (ex. Age ≥45 years old 5. Race/ethnicity 4. usually in the second or third trimester.3. PREVENTION of DIABETES MELLITUS 1. Always see your Doctor for follow-up check up. ≥20% over desired body weight or BMI ≥27 KG/M2) 3. Previously identified impaired fasting glucose or impaired glucose tolerance. 4. Family History of Diabetes (ex. Exercise Proper Diet . 2. Onset during pregnant. 6. Hypertension 7. 5. Parents or siblings with diabetes). 3. Change in lifestyle Drink Maintenance Medicine all the time. HDL cholesterol level ≤35 mg/dL 8. History of Gestational Diabetes. Gestational Diabetes a. which inhibit secretion of insulin RISK FACTORS for DIABETES MELLITUS 1. Due to hormones secreted by placenta. 2. b.

b. stroke) Peripheral Disease Gas gangrene Kidney Disease Eye Disease Disease of the nerve. Polydipsia. 4. Polyuria. Weakness Sudden vision changes Tingling or numbness in the hands and feet Dry skin Skin lesions or wounds that are slow to heal Recurrent infection. e. Macrovascular Complication (coronary artery disease) . COMPLICATION of DIABETES MELLITUS 1. 3. d.CLINICAL MANIFESTATION of DIABETES MELLITUS The Three (3) P’s SYMPTOMS of diabetes: 1. f. 3. 6. 2. refers to increased in appetite. refers to increased in thirst. c. 2. Polyphagia. Cardiovascular Disease (Myocardial infarction. refers to increased in urination. 7. 5. Other symptoms: a.

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