Drug Name

Classification

Dosage and Route of Administration

Action

Indication

Contraindicat ion

Side Effects/ Adverse Effects

Nursing Responsibilities

Generic Name: Furosemide Brand Name: Lasiz Electrolytic and water balance agent; Loop diuretic

Dosage: 40mg/IV Route: Per Orem Frequency: Every 8 hours

Rapid-acting potent sulfonamide "loop" diuretic and antihypertensive with pharmacologic effects and uses almost identical to those of ethacrynic acid. Exact mode of action not clearly defined; decreases renal vascular resistance and may increase renal blood flow.

 Treatment of edema associated with CHF, cirrhosis of liver, and kidney disease, including nephrotic syndrome. May be used for management of hypertension, alone or in combination with other antihypertensive agents, and for treatment of hypercalcemia. Has been used concomitantly with mannitol for treatment of severe cerebral edema, particularly in meningitis.

History of hypersensitivi ty to furosemide or sulfonamides ; increasing oliguria, anuria, fluid and electrolyte depletion states; hepatic coma

CNS: Headache GI: Nausea, vomiting, oral and gastric burning, anorexia, diarrhea, constipation, abdominal cramping, acute pancreatitis, jaundice. CV: Postural hypotension, dizziness with excessive diuresis, acute hypotensive episodes, circulatory collapse.

1. Observe patients receiving parenteral drug carefully; closely monitor BP and vital signs. Sudden death from cardiac arrest has been reported. 2. Monitor BP during periods of diuresis and through period of dosage adjustment. 3. Observe older adults closely during period of brisk diuresis. Report symptoms to physician. 4. Lab tests: Obtain frequent blood count, serum and urine electrolytes, CO2, BUN, blood sugar, and uric acid values during first few months of therapy and periodically thereafter. 5. Monitor for signs and symptoms of hypokalemia.

Patients who are pregnant, lactation.