B

Course Code:

T

C

0

2

3

Course Title:

Immunology and Immuno technology

L 3

T 0

P 2

Cr 4

CA 40

Weightage MTE 15

ETE 45

Pre-requisites: Nil Course Contents: S.no .

Topic

1.

Terminology of immune system; Types of immunity: innate and adaptive; Features of immune response and memory; humoral and cell mediated immunity.

Approximate No. of Lectures (Scheduled Keeping total as 7*L) 2

2. 3. 4. 5. 6 7

Cells of immune system: lymphoid cells and myeloid cells.

2 3 1 3 2 3

Organs of immune system. Nature of antigen; Factors influencing immunogenicity Antibody structure, function and classes. Monoclonal antibodies Antigen antibody interaction, affinity and avidity. Various types of immunodiffusion and immunoelectrophoretic procedures: Immunoblot, ELISA, RIA, Haemagglutination assay. MHC, MHC molecules and genes. Antigen processing and presentation: Cytosolic and Endocytic pathway. The complement system. Introduction to cytokines Hypersensitivity and its types. Introduction to Autoimmunity, Immunodeficiencies Immunity to viruses, bacteria, fungi.

8 9 10 11 12 13 14

2 2 3 2 3 3 2

15 16

Tumors Graft rejection
TOTAL

1 2 36

Laboratory Work:

1. To determine blood group of own blood. To determine total leucocyte count 2. To separate serum from blood. To determine species of origin. 3. Double Immunodiffusion 4. Immunoelectrophoresis 5. Radial Immunodiffusion 6. Dot ELISA 7. Latex agglutination 8. Isolation of lymphocyte population. 9. Macrophages extraction.
Textbook 1. Kuby immunology, By :- Thomas J. Kindt, Barbara A. Osborne, & Richard A. Goldsby.

Additional Readings: 1. Basic immunology:- Functions and disorders of the immune system. By:- Abul K Abbas, & Andrew A. Lichtman 2. Immunology, (Lippincotts Illustrated Review) By:- Thao Doan, Roger Melvold, Susan Viselli, Carl Waltenbaugh. 3. Immunology- By;- Ivan Roitt.

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