Drug Name

Dosage & Route

Action Synthetic sympathomimetic amine and moderately selective beta2-adrenergic agonist with comparatively long action. Acts more prominently on beta2 receptors (particularly smooth muscles of bronchi, uterus, and vascular supply to skeletal muscles) than on beta1 (heart) receptors. Minimal or no effect on alphaadrenergic receptors. Inhibits histamine release by mast cells.

Indication

Adverse Effects

Contraindication Pregnancy (category C), lactation. Use of oral syrup in children <2 y.

Nursing Responsibility

ALBUTEROL (al-byoo'ter-ole)) Accuneb, Novosalmol , Proventil, Proventil HFA, Proventil Repetabs, Salbutamol, Ventolin, Ventolin Rotocaps, Volmax Classifications: autonomic nervous system agent; betaadrenergic agonist (sympathomimetic); bronchodilator (respiratory smooth muscle relaxant)

Bronchospasm Adult: PO 2–4 mg 3–4 times/d, 4–8 mg sustained release 2 times/d Inhaled 1–2 inhalations q4–6h Child: PO 2–6 y, 0.1–0.2 mg/kg t.i.d. (max: 4 mg/dose); 6–12 y, 2 mg 3–4 times/d; Inhaled 6– 12 y, 1–2 inhalations q4–6h

To relieve bronchospasm associated with acute or chronic asthma, bronchitis, or other reversible obstructive airway diseases. Also used to prevent exerciseinduced bronchospasm.

Body as a Whole: Hypersensitivity reaction. CNS: Tremor, anxiety, nervousness, restlessness, convulsions, weakness, headache, hallucinations. CV: Palpitation, hypertension, hypotension, bradycardia, reflex tachycardia. Special Senses: Blurred vision, dilated pupils. GI: Nausea, vomiting. Other: Muscle cramps, hoarseness.

Assessment & Drug Effects

Monitor therapeutic effectiveness which is indicated by significant subjective improvement in pulmonary function within 60–90 min after drug administration. Monitor for: S&S of fine tremor in fingers, which may interfere with precision handwork; CNS stimulation, particularly in children 2–6 y, (hyperactivity, excitement, nervousness, insomnia), tachycardia, GI symptoms. Report promptly to physician. Lab tests: Periodic ABGs, pulmonary functions, and pulse oximetry. Consult physician about giving last albuterol dose several hours before bedtime, if drug-induced insomnia is a problem.