Fluids and Electrolytes Review

Philippine Integrated Nurse Licensure Examination

Sample Question
 The

nurse is caring for a client with Congestive Heart Failure. On assessment, the nurse finds the client complaining of dyspnea and that rales are heard on auscultation. The nurse suspects fluid volume excess. Which additional sign would the nurse expect if fluid volume excess is present? A. B. C. D. Flat neck and hand veins Weight loss Increased central venous pressure Hypotension

Key to Success!
 Confidence

+  Adequate test Preparation and review +  Effective test taking strategy +  Good study habits +  Working Knowledge of Basic Nursing concepts = Success in passing PINLE

Fluids and Electrolytes Outline
3 concepts
 Fluids  Electrolytes  Acids

and Bases

Important Concepts
 Remember

the ABC  Safety of the patient  Maslow’s Hierarchy of needs  Utilize the NURSING PROCESS ◦ A-D-P-I-E

Summary of Subtopics
 Basic Definition  Body Proportions and Distributions  Sources  Dynamics  Regulation by 3 systems- renal, endocrine

GIT  Balance  Imbalances  Application of the Nursing Process in the discussion



solution of solvent and solutes  Our body is made up of fluids and solids  About 50-60% of the body weight is WATER  In a 70 Kg adult male: 60% X 70= 40-42 Liters  Note that 1 kg body weight= 1 liter of water  The body has two major compartments: 1 Intracellular 2. Extracellular

The Proportion of Body Fluids
Interstitial 15%

Intracellular fluid 40%

Intravascula r 5%
Transcellular 1-2%

The Intracellular Fluid
 Found  This

inside the cell surrounded by a membrane.

is compartment with the highest percentage of water in adults.

The Extracellular Fluid
 Fluid

found outside the cells


Found in between the cells Found inside the blood vessels and lymphatic vessels Found inside body cavities like pleura, peritoneum, CSF



Sample question
1. A client with CHF is assessed by the nurse. Upon reviewing the chart, it is determined that his weight increased by 4.5 pounds. The nurse estimates that client has gained how many liters of fluid? A. 3 B. 1 C. 2 D. 0.5

Sources of Fluids: Fluid Input
1. Exogenous sources  Fluid intake- water from foodstuffs  IVF  Medications  Blood products 2. Endogenous sources  By products of metabolism  secretions

Fluid Losses
Routes of Fluid output  Urine Sensible losses  Fecal losses  Sweat  Insensible losses though the skin and lungs as water vapor

Sample question
2. A nurse reads a doctor’s progress notes in the client’s chart which states “insensible fluid loss approximately 800 ml.” The nurse understands that this fluid loss may occur through: A. The Gastrointestinal tract B. Urinary output C. Wound drainage D. The skin

Sample question
A nurse is administering IVF as ordered to a patient who sustained second-degree burns. In evaluating the adequacy of fluid resuscitation, the nurse understands that the most reliable indicator for fluid adequacy is the: A. Blood pressure B. Mental status C. Urine output D. Peripheral pulses

Sample question
The nurse receives the following endorsements. She is certain that which patient is at most risk for the development of fluid volume deficit? a A. The client who came from the OR after

hemorroidectomy. B. The client who has Renal failure undergoing dialysis. C. The client with AIDS taking corticosteroids. D. The client with Rheumatic fever taking diuretics.

Fluid Dynamics
The movement of fluids (solutes and solvents) in the body compartment  Diffusion  Osmosis  Filtration  Active transport

The Concept of TONICITY
 This

is the concentration of solutes in a solution.  A solution with high solute concentration is considered as HYPERTONIC.  A solution with low solute concentration is considered as HYPOTONIC.  A solution having the same tonicity as that of body fluid or plasma is considered ISOTONIC.

Helpful Hints
 In

a HYPERTONIC solution, fluid will go out from the cell, the cell will shrink.  In a HYPOTONIC solution, fluid will enter the cell, the cell will swell.  In an ISOTONIC solution, there will be no movement of fluid.

 The

movement of SOLUTES or particles in a solution from a higher concentration to a lower concentration.  If a sugar is placed in plain water, the glucose molecules will dissolve and diffuse distribute in the solution.

 The

force that draws water or solvent from a less concentrated solution into a more concentrated solution through a semi-permeable membrane.  The pressure that draws water inside the vessel which is more concentrated is called Osmotic pressure.  A special type of osmotic pressure is exerted by the proteins in the plasma. It is called ONCOTIC PRESSSURE.

Sample question

The nurse is caring for a psychiatric patient who ingested high-sodium containing foods. She suspects hypernatremia in this patient and expect to note: A. Hyperactive deep tendon reflex B. Chovstek’s Sign C. Dry skin and sticky mucous membrane D. Decreased muscle tone

 The

movement of both solute and solvent by hydrostatic pressure, ie, from an area of a higher pressure to an area of a lower pressure.  An example of this process is urine formation.  Increased hydrostatic pressure is one mechanism producing edema.

Active transport
 This

is the movement of solutes across a membrane from a lower concentration to a higher concentration with utilization of energy.  Example is the Sodium-Potassium pump- a primarily active transport process.

Sample question

The nurse reviews the laboratory report of a patient with fluid volume deficit. Which of the following laboratory findings will support this condition? A. WBC count of 9,000 B. Creatinine of 1 mg/dl C. Sodium of 140 mEq/L D. Hematocrit of 58%

Sample question

The client is taking a high dose of Furosemide. To determine the progress of the therapy, the nurse performs which of the following important action? A. Monitor urinary pH B. Check the temperature periodically C. Weight the patient daily D. Obtain a serial serum Sodium level

Regulation of Body fluid balance
1. The Kidney  Regulates primarily fluid output by urine formation  Releases RENIN  Regulates sodium and water balance

Regulation of Body fluid balance
2. Endocrine regulation  Regulates primarily fluid intake by thirst mechanism  ADH increase water reabsorption on collecting duct  Aldosterone increases Sodium retention in the distal nephron  ANF Promotes Sodium excretion and inhibits thirst mechanism

Regulation of Body fluid balance
3. Gastro-intestinal regulation  The GIT digests food and absorbs water  Only about 200 ml of water is excreted in the fecal material per day

 Electrolytes

are charged ions capable of

conducting electricity and are solutes in all compartment.  ANIONS are Negatively charged ions: Bicarbonate, chloride, PO4 CATIONS are positively charged ions: Sodium, Potassium, magnesium, calcium.

Helpful mnemonics
 PI-SO  Potassium

is inside  Phosphate is inside  Sodium is outside  Chloride is outside

Regulation of Electrolyte Balance
1. Renal regulation  Occurs by the process of glomerular filtration, tubular reabsorption and tubular secretion.  Urine formation ◦ If there is little water in the body, it is conserved. ◦ If there is water excess, it will be eliminated.

Regulation of Electrolyte Balance
2. Endocrinal regulation  Hormones play a role in electrolyte regulation  Aldosterone promotes Sodium retention and Potassium excretion  ANF promotes Sodium excretion  Parathormone promotes Calcium retention and Phosphate excretion  Calcitonin promotes Calcium excretion and Phosphate excretion


 The MOST ABUNDANT cation in the ECF  Normal range is 135-145 mEq/L  Major contributor of plasma osmolarity

FUNCTIONS  1. participates in the Na-K pump  2. assists in maintaining blood volume  3. assists in nerve transmission and muscle contraction  Aldosterone increases sodium retention  ANF increases sodium excretion

 MOST ABUNDANT cation in the ICF  Normal range is 3.5-5.0 mEq/L  Major electrolyte maintaining ICVF

FUNCTIONS  1. maintains ICF Osmolality  2. nerve conduction and muscle contraction  3. metabolism of carbohydrates, fats and protein  Aldosterone promotes renal excretion of K+  Acidosis promotes exchange of K+ for H+ in the cell


 Majority

of calcium is in the bones and teeth  Normal serum range 8.5-10 mg/dL FUNCTIONS  1. formation and mineralization of bones/teeth  2. muscular contraction and relaxation  3. cardiac function  4. blood clotting  5. enzyme activation

Regulation:  GIT absorbs Ca+ in the intestine with the help of Vit. D  Kidney Ca+ is filtered in the glomerulus and reabsorbed in the tubules  PTH increases Ca+ by bone resorption, Ca+ retention and activation of Vitamin D  Calcitonin released when Ca+ is high, it decreases Ca+ by excretion in the kidney

 Second  Normal

to K+ in the ICF range is 1.3-2.1 mEq/L FUNCTIONS  1. intracellular production and utilization of ATP  2. protein and DNA synthesis  3. neuromuscular irritability


 The MAJOR Anion in the  Normal range is 95-108


FUNCTIONS  1. major component of gastric juice aside from H+  2. together with Na+, regulates plasma osmolality  3. participates in the chloride shift  4. acts as chemical buffer

 The

MAJOR Anion in the ICF  Normal range is 2.5-4.5 mg/L FUNCTIONS  1. component of bones  2. needed to generate ATP  3. components of DNA and RNA  PTH decreases PO4 in blood by renal excretion  Calcitonin increases renal excretion of PO4

 Present

both in ICF and ECF  Normal range- 22-26 mEq/L FUNCTION  1. regulates acid-base balance  2. component of the bicarbonate-carbonic acid buffer system

1. HYPERNATREMIA  More than 145 mEq/L  Fluid moves out of cell crenation  Etiology:↑ sodium intake, IVF, water loss in excess of water, diarrhea  S/SX: dry, sticky tongue, thirst

2. HYPERKALEMIA  K+ more than 5.0 mEq/L  Etiology: IVF with K+, acidosis, Hyperalimentation and K+ replacement  ECG: peaked T waves and wide QRS

3. HYPERCALCEMIA  Serum calcium more than 10.5 mg/dL  Etiology: Overuse of calcium supplements, excessive Vit. D, malignancy, prolonged immobilization, thiazide diuretic  ECG: Shortened QT interval

4. HYPERMAGNESEMIA  Serum magnesium more than 2.1 mEq/L  Etiology: use of Mg antacids, Renal failure, Mg medications  S/SX: depressed tendon reflexes, oliguria, ↓RR

5. HYPERCHLOREMIA  Serum chloride more than 108 mEq/L  Etiology: sodium chloride excess


PO4 more than 4.5 mg/dL  Etiology: Tissue trauma, chemotherapy. PO4 containing medications, osteoporosis

1. HYPONATREMIA  Na level is less than 135 mEq/L  Water is drawn into the cell cell swelling  Etiology: prolonged diuretic therapy, excessive burns, excessive sweating, SIADH, plain water consumption  S/SX: nausea, vomiting, seizures

2. HYPOKALEMIA  K+ level less than 3.5 mEq/L  Etiology: use of diuretic, vomiting and diarrhea  ECG: flattened , depressed T waves, presence of “U” waves

3. HYPOCALCEMIA  Calcium level of less than 8.5 mg/dL  Etiology: removal of parathyroid gland during thyroid surgery, vit. D deficiency, Furosemide, infusion of citrated blood  s/sx: Tetany, (+) Chovstek’s (+) Trousseaus’s  ECG: prolonged QT interval

 Acid-

substance that can donate or release hydrogen ions ◦ Carbonic acid, Hydrochloric acid

 Base-

substance that can accept hydrogen ions ◦ Bicarbonate

 Buffer-

substance that can accept or donate hydrogen ◦ Hemoglobin buffer ◦ Bicarbonate : carbonic acid buffer ◦ Phosphate buffer

 Acid-

ions ◦ Carbonic acid, Hydrochloric acid  Base- substance that can accept hydrogen ions ◦ Bicarbonate  Buffer- substance that can accept or donate hydrogen ◦ Hemoglobin buffer ◦ Bicarbonate : carbonic acid buffer ◦ Phosphate buffer

substance that can donate or release hydrogen

Helpful Hints
 Carbon

dioxide is considered to be ACID because of its relationship with carbonic acid  pH measures the degree of acidity and alkalinity. It is inversely related to Hydrogen. Normal ph 7.35-7.45  Decreased pH- ACIDIC-increased Hydrogen— pH below 7.35  Increased pH- ALKALOSIS-decreased hydrogen —pH above 7.45


high hydrogen acidic pH is low  a low hydrogen alkalosis pH is high

high CO2may mean acidic  a low CO2 may mean alkalosis

Dynamics of Acid and bases
 Acids

and bases are constantly produced in the bo  They must be constantly regulated.  CO2 and HCO3 are crucial in the balance.  A ratio of 20:1 is maintained (HCO3:H2CO3)  Respiratory and renal system are active in regulati

Ways to balance the acids and bases
Excretion  Acid can be excreted, and Hydrogen can be excreted in ACIDOTIC condition.  Bicarbonate can be excreted in ALKALOTIC condition.

Ways to balance the acids and bases
Production  Bicarbonate can be produced in ACIDOTIC condition.  Hydrogen can be produced in ALKALOTIC condition.

Ways to balance the acids and bases
The respiratory system compensates for metabolic problems  CO2 (acid) can be exhaled from the body to normalize the pH in ACIDOSIS.  CO2 (acid) can be retained in the body to normalize the pH in ALKALOSIS.

Ways to balance the acids and bases

The kidney can compensate for problems in the respiratory system  The Kidney reabsorbs and generates Bicarbonate (alkaline) in ACIDOSIS.  The Kidney can excrete H+ excess (Acidosis) to normalize the pH in ACIDOSIS.

Ways to balance the acids and bases
 The

kidney can excrete bicarbonate (alkali) in conditions of ALKALOSIS.  The kidney can retain H+ (acid) in conditions of ALKALOSIS.

Ways to balance the acids and bases
Chemical buffers can also participate in the balance of acid-base  1. Carbonic acid- bicarbonate buffer  2. Phosphate buffer  3. protein buffer- ICF and hemoglobin The action is immediate but very limited

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