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Table 1.

Gender distribution

Sex
Pathological findings Chi-
Benign Malignant Total
squar
e P-
n % n % n % value value
F 9 47.4 11 35.5 20 40

M 10 52.6 20 64.5 30 60 0.693 .405


Total 19 100 31 100 50 100

Table 2. Clinical features

Clinical Pathological findings Chi-


Features squar
Benign Malignant Total
e P-
n % n % n % value value
Anorexia
NO 10 52.6 0 0 10 20
YES 9 47.4 31 100 40 80 20.395 0.000
Total 19 100 31 100 50 100
Loss of weight

NO 17 89.5 7 22.6 24 48

YES 2 10.5 24 77.4 26 52 21.118 0.000

19 100 31 100 50 100


Total
Table 3. Age and Laboratory parameters

Parameters Pathological findings


Benign Malignant
t- P-
Mean SD Mean SD value value
Age 62.47 11.946 63.06 9.515 0.193 0.848
CA 19-9 125.868 242.5380 642.494 404.3299 5.031 0.000
Alkaline Phosphatase 435.89 240.479 511.87 311.838 0.908 0.368
Total Serum Bilirubin 164.71 108.156 278.90 151.595 2.862 0.006

AUC
0.858

Fig. CA19-9
AUC
0.568

Fig. Alkaline Phosphatase

AUC
0.731

Fig. Total serum bilirubin


Table 4. ROC parameters of Laboratory findings
Cut-off Sensitivit Specificit Area under P-
Parameter value y (%) y (%) Curve (AUC) value
Total Bilirubin
(µmol/L) 135.32 52.6 83.9 0.731 0.007
Alkaline Phosphatase
(U/L) 478 63.2 41.9 0.568 0.424
CA 19-9 (U/ml) 100 73.9 77.4 0.858 0.001

Area Under the Curve


Test Result Variable(s) Asymptotic 95% Confidence
Interval
a b
Area Std. Error Asymptotic Sig. Lower Bound Upper Bound
CA19_9 .858 .057 .000 .747 .970

dimensio n0
ALP .568 .084 .424 .403 .733
TSB .731 .073 .007 .587 .875
The test result variable(s): CA19_9, ALP, TSB has at least one tie between the positive actual state group
and the negative actual state group. Statistics may be biased.
a. Under the nonparametric assumption
b. Null hypothesis: true area = 0.5
Fig. AP Benign

Area Under the Curve


Test Result Variable(s):AP
Asymptotic 95% Confidence
Interval
a b
Area Std. Error Asymptotic Sig. Lower Bound Upper Bound
.845 .055 .000 .737 .952
The test result variable(s): AP has at least one tie between the positive actual
state group and the negative actual state group. Statistics may be biased.
a. Under the nonparametric assumption
b. Null hypothesis: true area = 0.5
Fig. PP malignant

Area Under the Curve


Test Result Variable(s):PP
Asymptotic 95% Confidence
Interval
Area Std. Errora Asymptotic Sig.b Lower Bound Upper Bound
.829 .067 .000 .698 .959
The test result variable(s): PP has at least one tie between the positive actual
state group and the negative actual state group. Statistics may be biased.
a. Under the nonparametric assumption
b. Null hypothesis: true area = 0.5