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and typically rather large . which would usually be necessary if there are both quantitative and qualitative factors present. Designs with factors at two and four levels that are of resolution IV or higher. If all factors are quantitative. However . we recommend using designs cautiously .Conclusion from CH. requiring n 32 runs in many cases.and four level factors available. The system with center points will usually be a superior alternative.9 There are a wide range of fractional factorial designs with a mix of two. .

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