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Generic Name: furosemide

Brand Name: Lasix


Classification: loop diuretics
Dosage: IV (Adults): 20–40 mg, may repeat in 1–2hr and increase by 20 mg every 1–2 hr
Indication: Edema due to heart failure, hepatic impairment or renal disease, hypertention
Action:
Inhibits the reabsorption of sodium and chloride from the loop of Henle and distal renal tubule.
Increases renal excretion of water, sodium, chloride, magnesium, potassium, and calcium
Therapeutic Effect: Diuresis and subsequent mobilization of excess fluid (edema)
Adverse Reaction/Side effect:
CNS: blurred vision, dizziness, headache, vertigo.
EENT: hearing loss, tinnitus.
CV: hypotension.
GI: anorexia, constipation, diarrhea, dry mouth, and dyspepsia, nausea, vomiting
GU: excessive urination.
Derm: photosensitivity, pruritis, rash.
Endo: hyperglycemia, hyperuricemia
F and E: dehydration, hypocalcemia, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia,
metabolic alkalosis, hypovolemia
Contraindication:

Hypersensitivity; cross-sensitivity with thiazides and sulfonamides may occur; Hepatic coma or anuria.
Use cautiously in: Severe liver disease (may precipitate hepatic coma; concurrent use with potassium-
sparing diuretics may be necessary); Geriatric patients may have increased risk of side effects,
especially hypotension and electrolyte imbalance, at usual doses.

Nursing Responsibilities:

1. Monitor blood pressure and pulse before and during administration

2. Assess fluid status. Monitor daily weight take and output ratios, amount and location of edema,
lung sounds, skin turgor, and mucous membranes. Notify physician or other health care
professional if thirst, dry mouth, lethargy, weakness, hypotension, or oliguria occurs.

3. Assess patients receiving digoxin for anorexia, nausea, vomiting, muscle cramps, paresthesia, and
confusion. Patients taking digoxin are at increased risk of digoxin toxicity because of the
potassium-depleting effect of the diuretic

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