Name of Drugs Brand/Generic

Generic: Epinephrine Brand: EpiPen, SusPhrine

Action & Classification of Drugs
Naturally occurring catecholamine obtained from animal adrenal glands; also prepared synthetically. Acts directly on both alpha and beta receptors; the most potent activator of alpha receptors. Strengthens myocardial contraction; increases systolic but may decrease diastolic blood pressure; increases cardiac rate and cardiac output.

Dose, Route & Frequency

Indication & Contraindication
For asthma, chronic bronchitis, acute anaphylactic reactions/allergies. Ophthalmic preparation is used in management of simple (open-angle) glaucoma, generally as an adjunct to topical miotics and oral carbonic anhydrase inhibitors; also used as ophthalmic decongestant.

Side effects & Adverse Reactions
Side Effects:  Bronchodilation, palpitations, tachycardia, dizziness, nervousness, insomnia. Adverse Effects:

Nursing Responsibilities
Know the 10 Right of medication Administration 1. Right medication 2. Right amount 3. Right patient 4. Right manner & route 5. Right time 6. Right documentation 7. Right assessment 8. Right education 9. Right evaluation 10. Right to refuse to medication.
> Monitor BP, pulse, respirations, and urinary output and observe patient closely following IV administration. Epinephrine may widen pulse pressure. If disturbances in cardiac rhythm occur, withhold epinephrine and notify physician immediately.

Sympathomimetic, direct acting

Adult: SC 0.1–0.5 mL of 1:1000 q10–15min prn IV 0.1–0.25 mL of 1:1000 q10–15min Child: SC 0.01 mL/kg of, 1:1000 q10–15min prn IV 0.01 mL/kg of 1:1000 q10–15min Neonate: IV Intratracheal 0.01– 0.03 mg/kg (0.1–0.3 mL/kg of 1:10,000) q3– 5min prn Asthma Adult: SC 0.1–0.5 mL of 1:1000 q20min– 4h Inhalation 1 inhalation q4h prn Child: SC 0.01 mL/kg of 1:1000 q20min– 4h Inhalation 1 inhalation q4h prn

 Nervousness,
restlessness, sleeplessness, fear, anxiety, tremors, severe headache, cerebrovascular accident, weakness, dizziness, syncope, pallor, sweating, dyspnea.

Hypersensitivity to sympathomimetic amines; narrow-angle glaucoma; hemorrhagic, traumatic, or cardiogenic shock; cardiac dilatation, cerebral arteriosclerosis, coronary insufficiency, arrhythmias, organic heart or brain disease.Safety during pregnancy (category C) or lactation is not established.