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• An extended linear regression technique in which a nonlinear mathematical model is used to describe the relationship between the response variable and the predictor variables. • A nonlinear regression model is a model that contains at least one of the parameters in a nonlinear form • Example

Violeta I. Bartolome

Senior Associate Scientist PBGB-CRIL v.bartolome@cgiar.org

Y = αXβ + ε

ε ~ N( 0, σ 2 )

**Linearized Nonlinear Model
**

• The linearized form of the example is:

Parameter Estimation

• Iterative procedures are used • May require users to supply initial estimates of parameters • User should know the biological interpretation of the parameters to provide intelligent initial values. • The function getInitial() may also be used.

**log Y = log α + β log X
**

• The normality assumption for the error term will not be appropriate for the linearized form. • Hence, if a nonlinear model is assumed to be appropriate for the data, the nonlinear model should be used for the analysis instead of the linearized form.

**Logistic growth curve
**

• Sample data

Severity represents the number of lesions on the leaf surface, standardized as a proportion of the maximum.

Read and Plot Data

Graph shows a logistic relationship. Logistic model:

y=

α 1 + eβ −rt

Initial values

SSlogis creates initial estimates of the parameters Asym, xmid, and scal from the model:

y= Asym 1+e

xmid−input scal

Estimate Parameters

α = Asym

β=

xmid scal

The model that we are estimating is: r = 1 scal

t = input

y=

α 1 + eβ −rt

Check fit of data

**Other Non-linear Models
**

• Exponential

**Other Non-linear Models
**

• Monomolecular

y = y0erx + ε

y = 1 − (1 − y0 )e −rx + ε

**Other Non-linear Models
**

• Logistic

**Other Non-linear Models
**

• Gompertz

y=

1 1 − y0 1+ y0e −rx

y = e log y0 e −rx

**Other Non-linear Models
**

• Weibull

x −a − b c

y = 1−e

Thank you!

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