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Mark Scheme (Results) Summer 2010

GCE

GCE Biology (6BI01/01)

Edexcel Limited. Registered in England and Wales No. 4496750 Registered Office: One90 High Holborn, London WC1V 7BH

Edexcel is one of the leading examining and awarding bodies in the UK and throughout the world. We provide a wide range of qualifications including academic, vocational, occupational and specific programmes for employers. Through a network of UK and overseas offices, Edexcel’s centres receive the support they need to help them deliver their education and training programmes to learners. For further information, please call our GCE line on 0844 576 0025, our GCSE team on 0844 576 0027, or visit our website at www.edexcel.com.

If you have any subject specific questions about the content of this Mark Scheme that require the help of a subject specialist, you may find our Ask The Expert email service helpful. Ask The Expert can be accessed online at the following link: http://www.edexcel.com/Aboutus/contact-us/ Alternatively, you can speak directly to a subject specialist at Edexcel on our dedicated Science telephone line: 0844 576 0037

Summer 2010 Publications Code US023567 All the material in this publication is copyright © Edexcel Ltd 2010

General Marking Guidance
• • All candidates must receive the same treatment. Examiners must mark the first candidate in exactly the same way as they mark the last. Mark schemes should be applied positively. Candidates must be rewarded for what they have shown they can do rather than penalised for omissions. Examiners should mark according to the mark scheme not according to their perception of where the grade boundaries may lie. There is no ceiling on achievement. All marks on the mark scheme should be used appropriately. All the marks on the mark scheme are designed to be awarded. Examiners should always award full marks if deserved, i.e. if the answer matches the mark scheme. Examiners should also be prepared to award zero marks if the candidate’s response is not worthy of credit according to the mark scheme. Where some judgement is required, mark schemes will provide the principles by which marks will be awarded and exemplification may be limited. When examiners are in doubt regarding the application of the mark scheme to a candidate’s response, the team leader must be consulted. Crossed out work should be marked UNLESS the candidate has replaced it with an alternative response.

• • •

• •

Quality of Written Communication Questions which involve the writing of continuous prose will expect candidates to: • • • write legibly, with accurate use of spelling, grammar and punctuation in order to make the meaning clear select and use a form and style of writing appropriate to purpose and to complex subject matter organise information clearly and coherently, using specialist vocabulary when appropriate. Full marks will be awarded if the candidate has demonstrated the above abilities. Questions where QWC is likely to be particularly important are indicated (QWC) in the mark scheme, but this does not preclude others.

6BI01_01 1006

a correct statement that is contradicted by an incorrect statement in the same part of an answer gains no mark – irrelevant material should be ignored • • 6BI01_01 1006 . the crossed out work can be ignored. ‘glicojen’ is acceptable whereas ‘glucagen’ is not e. for mitosis. No marks are awarded specifically for quality of language in the written papers. Use of English is however taken into account as follows: • the spelling of technical terms must be sufficiently correct for the answer to be unambiguous e. as far as it is possible to do so.g. Meaning of symbol Indicates the end of a marking point Indicates that credit should be given for other correct alternatives to a word or statement. ‘mytosis’ is acceptable whereas ‘meitosis’ is not candidates must make their meaning clear to the examiner to gain the mark.g.g. for glycogen. for amylase. If the candidate has crossed out work but written no new text. ‘ammalase’ is acceptable whereas ‘amylose’ is not e. except for the essays in the synoptic paper. the crossed out work for that question or part question should be marked. an error made in an early part of a question is penalised when it occurs but not subsequently. ‘illeum’ is acceptable whereas ‘ilium’ is not e. semi colon eq / oblique {} curly brackets () round brackets [] square brackets [CE] or [TE] Crossed out work If a candidate has crossed out an answer and written new text.GENERAL INFORMATION The following symbols are used in the mark schemes for all questions: Symbol . The candidate is penalised once only and can gain credit in later parts of the question by correct reasoning from the earlier incorrect answer. for ileum. as discussed in the Standardisation meeting Words or phrases separated by an oblique are alternatives to each other Indicate the beginning and end of a list of alternatives (separated by obliques) where necessary to avoid confusion Words inside round brackets are to aid understanding of the marking point but are not required to award the point Words inside square brackets are instructions or guidance for examiners Consecutive error / transferred error Spelling and clarity In general.g.

. Answer Question Number 1(e) D. Answer Question Number 1(f) C.Question Number 1(a) Answer Mark (1) Mark (1) Mark (1) Mark (1) Mark (1) Mark (1) Mark (1) A. Answer Question Number 1(g) A. Answer D. Answer Question Number 1(c) Question Number 1(d) C. Answer Question Number 1(b) C.

2. diastole / atrial systole . (2) 6BI01_01 1006 . atria / atrium.Question Number 2(a) Answer 1. aorta . 4. the {atrioventricular / bicuspid / tricuspid} valves are open / semi-lunar valves are closed . 3. vena cava . artery . 5. 2. left . Mark (5) Mark Question Number 2 (b) Answer 1.

Question Number 3(a)(i) Answer 1. idea that aqueous environment is {on two sides / cytoplasm and {environment / tissue fluid / eq}} . (two) fatty acid (tails) . reference to {hydrophobic / non polar / uncharged} part . Mark max (3) 6BI01_01 1006 . correct reference to ester bonds . 4. 2. 4. Mark max (3) Question Number 3(a)(ii) Answer 1. 3. 5. 3. phospholipids . reference to location of glycerol . reference to orientation of molecule in relation to water. 2. reference to {hydrophilic / polar / charged} part . phosphate (head) .

idea that {protein / carrier} changes shape . idea that molecule {binds / fits into} {protein / carriers} .Question Number 3(b) Answer Active transport: 1. [Submax 2 marks] Mark max (3) 6BI01_01 1006 . reference to proteins as {channels / gates / pores / carriers} . for {large / polar / charged} molecules (to pass through membrane) . 4. 8. reference to use of {ATP / energy} . 6. [Submax 2 marks] Facilitated diffusion: 5. 7. (molecules move) down a concentration gradient / eq . 3. 2. idea that {channels can open or close / carriers change shape} . (molecules move) against a concentration gradient / eq .

idea that {fluidity / movement / eq} allow membranes to fuse. Mark max (2) Mark Question Number 3(c)(ii) Answer 1. 2. 2. idea that both types of protein in fused cell in correct context .Question Number 3(c)(i) Answer 1. idea that {phospholipids / molecule A} allow {fluidity / movement/ eq} . max (2) 6BI01_01 1006 . 3. idea that {fluidity / movement / eq} allows protein to {move / intermingle / eq} . idea that the proteins are {intermingled / mixed / eq} . same original number of protein / eq . 3.

correct manipulation of figures to approximate the increase in levels of one of the blood components . statistics 3. max (1) 6BI01_01 1006 .Question Number 4(a)(i) Answer 1. 4. no indication of other variables / named variable / eq . Mark max (3) Mark Question Number 4(a)(ii) Answer Any one of the following ideas 1. spread of data. no indication of number in {samples / study / eq} 4. no indication of data analysis e. the levels are given as a {range / not one level / blood components within normal level range} 2. idea that frequent cocaine use results in {higher / an increase in / eq } levels in both blood components (compared to occasional use) . 2.g. idea that the levels of both the blood components are within the range for normal levels in occasional users . frequent use increases fibrinogen beyond normal range / eq . 3.

4. Mark max (2) 6BI01_01 1006 . 4. credit one correct detail of clotting process . 3. fibrinogen increases with (cocaine) use / eq . Mark max (4) Question Number 4(c) Answer 1. idea that a correlation is {a relationship between two factors / when one factor changes another factor changes} . If the blood is flowing slower then there is an increased chance of blood clotting / eq . reference to von Willebrand factor making the platelets stickier . 7. 5. 3. 8. (as a result) the blood clotting process is triggered / eq . 2. 6. reference to more fibrinogen resulting in the clot {being larger / growing faster } . reference to release of thromboplastin (from platelets) . as a result of {platelet stickiness /platelets sticking together} the {clot grows faster / blood flow is decreased / eq} . idea that von Willebrand factor results in platelets sticking to {the endothelium /each other} .Question Number 4(b) Answer (QWC – Spelling of technical terms (shown in italics) must be correct and the answer must be organised in a logical sequence) 1. idea that increased fibrinogen levels have not been shown to result in the increase in heart disease . heart attacks increase with cocaine use / eq . 2.

(thickened mucus) cannot be moved by {cilia / coughing} . reference to change in protein . 4. 6. 3. 7.Question Number *5(a) QWC Answer (QWC – Spelling of technical terms (shown in italics) must be correct and the answer must be organised in a logical sequence) 1. 8. 2. by osmosis / eq . reference to a different {amino acid / sequence of amino acids / eq} (on defective CFTR protein) . Mark max (5) 6BI01_01 1006 . water does not move out (of cells) / water moves in (to cells) /eq . 5. 10. 9. reference to role of protein in transporting chloride ions . reference to CFTR {protein / channel} eq . mucus (on cell surface) {is not diluted / becomes thicker / becomes stickier} / eq . reference to (chloride) ions not {moving out of cells / going into mucus} . reference to sodium ions moving in .

max (3) 6BI01_01 1006 . 2.Question Number 5(b)(i) Answer 1. 5. 5. 4. Mark max (2) Mark Question Number 5(b)(ii) Answer 1. idea that {bacteria / mucus containing the bacteria} cannot be removed (by cilia). idea that mucus {traps / eq} {bacteria / pathogens} . idea that mucus provides conditions for bacteria to {live / grow / develop / eq} . 4. credit correct manipulation of figures . reference to antibodies not being effective . 3. (increases) {from 0 to 25 / up to 25} . {constant /eq} 25 to 35 . reference to trauma caused by coughing . {decreases / eq} 35 to 45 . {increase / eq} with age . 2. 6. idea that resident {phagocytes / macrophages} cannot destroy bacteria . 3.

S starts to decrease at year 15 but P {decreases at 35 years / continues to increase} . S {stays constant / is at its highest} between 10 and 15 years but P {stays constant / is at its highest} between 25 and 35 years . After 7 years P is greater than S . 5. Mark max (2) 6BI01_01 1006 . Overall increase in P and decrease in S . At 0 more S than P / between 0 and 7 years S is greater than P . 6. 2. 3. Maximum P is greater than maximum S . 4.Question Number 5(b)(iii) Answer 1.

6. Activation energy 4. Mark max (4) Question Number 6(b) Answer 1. idea that there should be enough substrate molecules to saturate the enzyme . 4. 5. 2. speeds up (rate of) {reactions / processes} / eq . as substrate gets used up {by enzyme / in reaction / eq } . 3. By causing bonds to {break / weaken / form} / by increasing the number of collisions / eq . as reaction proceeds substrate concentration decreases / eq . {fastest / highest} rate / decreases after initial rate / eq . Mark max (2) 6BI01_01 1006 .Question Number 6(a) Answer 1. produced by {organisms /cells}. Biological catalyst 2. reference to {enzymes / biological catalysts} reducing activation energy / eq . 3. energy needed for a reaction to occur / eq . 5. substrate concentration should be constant (in each test) / eq . (to ensure that) substrate is not a limiting factor/ eq .

Mark (4) 6BI01_01 1006 . not room temperature time of reaction . buffer .Question Number 6(c) Answer Any two pairs pH . stopwatch . water bath . volume of {enzyme / substrate} . temperature . type of enzyme . not amount measuring cylinder / pipette . same batch of enzyme .

Mark (2) 6BI01_01 1006 . Mark max (2) Mark Question Number 7(b) Answer same treatment method as for drug S e. the number of {deaths / all events / eq} is {similar to / no higher than / less than} placebo group . idea that side effects more likely to show up . idea that it makes the {results / data / study} {representative / reliable} . 2.Question Number 7(a)(i) Answer Any two from: genetic. solvent used for drug S / saline / water / sugar tablet / empty capsule / eq . (1) Question Number 7(c) Answer idea that {CVD is not an immediate disease / side effects may take time to become apparent / need to see if drug works over a long time} . 2. Credit correct manipulation of figures . diet qualified. idea that there are {many potential risk factors / large variation between individuals}. Mark (1) Question Number 7(a)(ii) Answer 1.g. increasing age. high blood pressure. {inactivity / lack of exercise / eq} . male. 3. Mark (1) Question Number 7(d) Answer 1. smoking.

Question Number 7(e)(i) Answer 1.8) .8 – 8. Mark (1) 6BI01_01 1006 . correct subtraction (11. (3) Question Number 7(e)(ii) Answer it has been shown to reduce {CVD / stroke} / eq . 2.1). correct multiplication by 10 000 [Consequential errors apply] Mark ÷ 100 .7 and 11. 3.7 = 3. correct values selected (8.

3. reference to (virus acting as a) vector . 2. idea that {more rats survive / higher survival rate / lower death rate} . Mark (1) 6BI01_01 1006 . rats survive longer / eq . 4. 2. tumour has {decreased in size / grown less / eq} . Mark (1) Question Number 8(b)(iii) Answer idea that endorphins have pain-reducing properties / more {endorphins / endorphins secreting cells} produced . Mark max (3) Question Number 8(b)(i) Answer 1. 5. decrease in size quantified .Question Number 8(a) Answer 1. Mark (2) Question Number 8(b)(ii) Answer reference to {neurones in spinal cord / endorphins being made in spinal cord / spinal cord connects to brain / eq} . 80% . idea that virus is used to get the {gene / DNA} into the cells .

ref to decrease in tolerance in group given gene therapy {in last month / after two months} and (slight) increase in control group . between 2 weeks and 2 months there is an increase in tolerance in rats given gene therapy but control group {remains the same / drops (slightly)} / eq .Question Number 8(b)(iv) Answer 1. 5. 6. 3. in first {2 weeks / ½ month} level of tolerance is {(almost) the same in both groups slightly higher in control group} / eq . after the first 2 weeks the level of tolerance is higher in the rats given gene therapy / eq . 2. 4. credit correct comparative manipulation of figures . Mark max (3) 6BI01_01 1006 . {little change / eq} in control but treated rats {rise and fall / eq} .

NG18 4FN Telephone 01623 467467 Fax 01623 450481 Email publications@linneydirect.Further copies of this publication are available from Edexcel Publications. Mansfield. Adamsway.edexcel. London.com Order Code US023567 Summer 2010 For more information on Edexcel qualifications. WC1V 7BH 6BI01_01 1006 . please visit www. Registered in England and Wales no. Notts.com/quals Edexcel Limited.4496750 Registered Office: One90 High Holborn.

4496750 Registered Office: One90 High Holborn. Registered in England and Wales No.Mark Scheme (Results) June 2010 GCE GCE Biology (6BI02/01) Edexcel Limited. London WC1V 7BH .

please call our GCE line on 0844 576 0025.edexcel. For further information.com/Aboutus/contact-us/ Alternatively. or visit our website at www. occupational and specific programmes for employers. our GCSE team on 0844 576 0027.com. you can speak directly to a subject specialist at Edexcel on our dedicated Science telephone line: 0844 576 0037 Summer 2010 Publications Code US023556 All the material in this publication is copyright © Edexcel Ltd 2010 . Ask The Expert can be accessed online at the following link: http://www.edexcel. Through a network of UK and overseas offices.Edexcel is one of the leading examining and awarding bodies in the UK and throughout the world. We provide a wide range of qualifications including academic. If you have any subject specific questions about the content of this Mark Scheme that require the help of a subject specialist. vocational. you may find our Ask The Expert email service helpful. Edexcel’s centres receive the support they need to help them deliver their education and training programmes to learners.

Examiners should also be prepared to award zero marks if the candidate’s response is not worthy of credit according to the mark scheme. Full marks will be awarded if the candidate has demonstrated the above abilities. i. the team leader must be consulted. Examiners should mark according to the mark scheme not according to their perception of where the grade boundaries may lie. Candidates must be rewarded for what they have shown they can do rather than penalised for omissions. but this does not preclude others. Questions where QWC is likely to be particularly important are indicated (QWC) in the mark scheme. There is no ceiling on achievement. if the answer matches the mark scheme. Examiners must mark the first candidate in exactly the same way as they mark the last. Mark schemes should be applied positively. using specialist vocabulary when appropriate. Crossed out work should be marked UNLESS the candidate has replaced it with an alternative response. When examiners are in doubt regarding the application of the mark scheme to a candidate’s response. grammar and punctuation in order to make the meaning clear select and use a form and style of writing appropriate to purpose and to complex subject matter organise information clearly and coherently. • • • • • • Quality of Written Communication Questions which involve the writing of continuous prose will expect candidates to: • • • write legibly. Where some judgement is required. with accurate use of spelling. All the marks on the mark scheme are designed to be awarded. All marks on the mark scheme should be used appropriately. mark schemes will provide the principles by which marks will be awarded and exemplification may be limited. Examiners should always award full marks if deserved.e. .General Marking Guidance • • All candidates must receive the same treatment.

Meaning of symbol Indicates the end of a marking point Indicates that credit should be given for other correct alternatives to a word or statement. The candidate is penalised once only and can gain credit in later parts of the question by correct reasoning from the earlier incorrect answer. ‘ammalase’ is acceptable whereas ‘amylose’ is not e. ‘glicojen’ is acceptable whereas ‘glucagen’ is not e. the crossed out work can be ignored. ‘mytosis’ is acceptable whereas ‘meitosis’ is not candidates must make their meaning clear to the examiner to gain the mark. a correct statement that is contradicted by an incorrect statement in the same part of an answer gains no mark – irrelevant material should be ignored • • .g. as far as it is possible to do so. Use of English is however taken into account as follows: • the spelling of technical terms must be sufficiently correct for the answer to be unambiguous e. except for the essays in the synoptic paper.GENERAL INFORMATION The following symbols are used in the mark schemes for all questions: Symbol . for mitosis. as discussed in the Standardisation meeting Words or phrases separated by an oblique are alternatives to each other Indicate the beginning and end of a list of alternatives (separated by obliques) where necessary to avoid confusion Words inside round brackets are to aid understanding of the marking point but are not required to award the point Words inside square brackets are instructions or guidance for examiners Consecutive error / transferred error Spelling and clarity In general.g. semi colon eq / oblique {} curly brackets () round brackets [] square brackets [CE] or [TE] Crossed out work If a candidate has crossed out an answer and written new text.g.g. ‘illeum’ is acceptable whereas ‘ilium’ is not e. for ileum. for amylase. No marks are awarded specifically for quality of language in the written papers. the crossed out work for that question or part question should be marked. If the candidate has crossed out work but written no new text. for glycogen. an error made in an early part of a question is penalised when it occurs but not subsequently.

B. (2) Question Number 1 (b) (ii) Answer C. 2. Mark (3) 6BI02_01 1006 . Mark (2) Question Number 1 (a) (ii) Answer 1. {genotype / eq} . 172 (cm) . loci / locations / positions / eq . alleles . Mark (2) Mark Question Number 1 (b) (i) Answer 1. {environment / eq} .Question Number 1 (a) (i) Answer 1. 174 (cm) . 2. A. 2.

Question Number *2(a) QWC

Answer (QWC – Spelling of technical terms (shown in italics) must be correct and the answer must be organised in a logical sequence) 1. undifferentiated cell / eq ; 2. that can give rise to other {types of cell / eq }; 3. idea that no limit to division ; 4. correct reference to {totipotent / pluripotent /eq} ;

Mark

max (2)

Question Number 2(b)

Answer 1. cord blood /umbilical cord / placenta ; 2. {fertilised egg / zygote / eq} / blastocyst / (early) embryo ; 3. detail of site within blastocyst 4. bone marrow / eq ; 5. {brain / connective / skin / liver} cells / eq ; 6. addition of adult nucleus to enucleated egg cell ;

Mark

max (3) Mark

Question Number 2(c)(i)

Answer 1. decide on max age of embryo allowed for research / eq ; 2. idea of setting or considering {ethical / legal} aspects / judging what is acceptable / follow a code of practice ; 3. example of what {is / is not} acceptable ; 4. checking that source of stem cells is acceptable / eq ; 5. stopping of cloning (of humans) / eq ;

max 6. appropriate reference to unnecessary repeating of (2) research / eq ;

6BI02_01 1006

Question Number 2 (c)(ii)

Answer people involved in embryo research: 1. idea of being able to (fully) understand the science / recognise what is possible {benefits / risks / eq} / judge in an informed manner ; people not involved in embryo research: 2. idea of giving a {balanced /alternative / wider / named} view ;

Mark

(2)

6BI02_01 1006

Question Number 3 (a)(i) Question Number 3 (a)(ii) Question Number 3 (a)(iii) Question Number 3 (a)(iv)

Answer C;

Mark (1)

Answer B;

Mark (1)

Answer far right-hand box ;

Mark (1)

Answer Bacteria / Eubacteria / Archaebacteria / Archaea ;

Mark (1)

6BI02_01 1006

6. reference to {matrix / hemicelluloses / pectins / eq} ..Question Number *3(b)(i) QWC Answer (QWC – Spelling of technical terms must be correct and the answer must be organised in a logical sequence) 1. correct reference to arrangement of microfibrils (in primary cell wall) . 2. 3. cellulose . {bundle /correct stated number of}) cellulose molecules) . 5. 8. Mark max (4) 6BI02_01 1006 . as microfibrils . detail of different laying down arrangement (in secondary cell wall) /reference to lignin .g. reference to primary and secondary cell walls . detail of microfibril (e. (cellulose molecules) held together by hydrogen bonds / eq 4. 7.

(2) 6BI02_01 1006 . middle lamella .Question Number 3 (b)(ii) Answer Mark Feature described site where there was no cell wall and the cytoplasm linked the two adjacent cells dark line that is the boundary between one cell and the next cell Name of feature plasmodesmata / plasmodesma .

. 4. max (3) Mark (2) Mark (1) Mark 6BI02_01 1006 .Answer Question Number 4 (a) a b A B Mark D e d E (1) Question Number 4 (b) (i) Answer P = crista . R = outer (mitochondrial) membrane / envelope / double membrane . Mark (3) Question Number 4 (b)(ii) Answer 1. allows sperm to swim / eq . Question Number 4 (c)(i) Answer 0.065 (%) . 5. towards the {egg / eq} / {towards /along} the oviduct / eq . (they carry out) (aerobic) respiration . to {move / drive the / eq} {flagellum / tail} . Q = matrix . 2. 3. provide {ATP / energy / eq} . Question Number 4 (c)(ii) Answer 16 .

then A & then B . so is un-reactive / insoluble /no osmotic effect .5% in variety B / 5% in variety C) eq . 3.g. idea that it is {large / eq} . 2. made up of {many / eq} glucose (monomers) . but by differing percentages in all 3 varieties / C. 4. 6. more can be stored (in available space) / eq . credit correct manipulation of the data for 1 variety (e. 2. reference to branches / reference to (glycosidic) 1-6 bonds / amylopectin .Question Number 5 (a)(i) Question Number *5(a)(ii)QWC Answer {α/ alpha} glucose . increase in temperature {decreases / eq } (the mean percentage of amylose present)/ negative correlation . Mark max (2) 6BI02_01 1006 . {rapid / increased / eq } mobilisation of glucose units / eq .0 % in variety A / 1. 8. 5. 3. 7. molecule coiling / compact / reference to amylose /eq . by 4. reference to {energy / eq } storage / glucose is the respiratory substrate / synthesis of organic molecules / eq . Mark max (4) Question Number 5 (b)(i) Answer Allow converse 1. Mark (1) Answer (QWC – Spelling of technical terms must be correct and the answer must be organised in a logical sequence) 1.

(variety) B . some of the data for the lower temp falls within that of the higher temp . explanation of overlap e.Question Number 5 (b)(ii) Answer 1. idea that error bars for the 2 different temp regimes overlap . 4. idea of smallest difference between (means / amylose content) in B for the two different temp regimes . idea of {biggest error bars / widest spread} . 2. 5. 3. Mark max (3) 6BI02_01 1006 .g.

{greater / eq} genetic diversity (amongst the litter) / eq . 2. 2. 2. in a {habitat / eq } / at any one time . 3.Question Number 6(a) Answer Niche: 1. Species richness: 3. 4. (therefore) less likely to survive / eq . increased chance of fertilisation / pregnancy / eq . {within the community / ecosystem /habitat / environment / eq } . Mark max (3) Question Number *6 (b)(i)QWC Answer (QWC – Spelling of technical terms must be correct and the answer must be organised in a logical sequence) 1. 4. (therefore) more at risk of {extinction / eq} . Mark max (2) 6BI02_01 1006 . the {role / function / eq} (of a species / organism) . 3. increase in population size / eq . greater chance that will {survive / eq} . number of (different) species . Mark max (3) Question Number 6 (b)(ii) Answer 1. 4. (cheetah has) {lowest genetic diversity / least genetic variation } (of the listed cats) . correct reference to lack of adaptation / example / no selective advantage (when environment changes) .

4. Mark (1) 6BI02_01 1006 . Mark max (2) Question Number 6 (d) Answer cheetahs that are exclusive to one continent . (which) reduces genetic diversity / eq . increases genetic diversity /eq . 2. 3.Question Number 6 (c) Answer 1. (because it) allows {outbreeding / mating / eq} with (genetically) different individuals / eq . stop/reduces {inbreeding / mating with parents / siblings} .

Mark (2) Mark Question Number 7 (a) (ii) Answer Labelled structure A B C D E Tick ( ) if chromosome number increases at fertilisation Comments given if more than 2 ticks and if use cross or crosses and ticks (2) 6BI02_01 1006 . from pollen grain. 2.g. down style to start of ovary . line drawn correctly e.Question Number 7 (a)(i) Answer 1. to micropyle (around the edge) .

Mark (1) Mark (1) Question Number 7 (b)(iii) Question Number 7 (b)(iv) Answer 1. idea of fertilisation in shorter time period . Mark max (2) 6BI02_01 1006 . correct comparative manipulation of the data .Question Number 7 (b)(i) Answer 1. 5. 2. fertilisation more likely to occur /eq . 3. idea of rate of growth greater with boron . 3. linear without boron (for 25 / 30 hours) and not linear with boron / eq . Answer boron {increases / speeds up / eq} rate . 4. Mark max (3) Question Number 7 (b)(ii) Answer idea that pollen tube does grow even in the absence of boron . 2. both {increase / positive correlation / eq} . more likely to reach the ovule /eq . (pollen tube) length (always) {greater/ eq} when boron present / eq .

only two concentrations were used / additional nitrate ion concentrations should be used . Mark (2) Mark Question Number 8 (a)(ii) Answer 1. 2. manipulation of the data (e. no {trend / eq} (as only 2 data sets) . If one of the two sets of data was {anomalous / eq} . One appropriate precaution.Question Number 8 (a)(i) Answer 1. by 6 cells (per 500 cells) / reduces by 24%) . (3) 6BI02_01 1006 . 3. . 4. reference to one with no nitrate ions present . (increasing or doubling nitrate ion concentration) decreased mitosis / negative correlation / eq . max (2) Mark Question Number 8 (a)(iii) Answer Two appropriate safety risks given . linked to one of the risks above . 2.g.

2. reference to uniformity of seedlings (e. light intensity. 3. temp.g. 3 + / sensible range of nitrate ion concentrations . all from same parent plant. reference to mechanism of judging root {growth /eq} (to measure optimum nitrate concentration) .Question Number 8 (b) Answer 1. reference to repeats (at each concentration) . mention one other variable maintained / kept constant (e. all run for same length of time. 4. Mark max (3) 6BI02_01 1006 . 6.g. 5. idea that solution used should contain other mineral ions / named mineral ions . same original root length) . volume of mineral solution) . same age.

Registered in England and Wales no. NG18 4FN Telephone 01623 467467 Fax 01623 450481 Email publications@linneydirect.com/quals Edexcel Limited. Mansfield. please visit www. Notts.4496750 Registered Office: One90 High Holborn.edexcel. Adamsway. London.com Order Code US023556 Summer 2010 For more information on Edexcel qualifications.Further copies of this publication are available from Edexcel Publications. WC1V 7BH 6BI02_01 1006 .

4496750 Registered Office: One90 High Holborn. Registered in England and Wales No. London WC1V 7BH .Mark Scheme (Results) June 2010 GCE GCE Biology (6BI07/01) Edexcel Limited.

Edexcel is one of the leading examining and awarding bodies in the UK and throughout the world.edexcel.com. If you have any subject specific questions about the content of this Mark Scheme that require the help of a subject specialist. We provide a wide range of qualifications including academic. occupational and specific programmes for employers. or visit our website at www.edexcel. For further information. you can speak directly to a subject specialist at Edexcel on our dedicated Science telephone line: 0844 576 0037 Summer 2010 Publications Code US023567 All the material in this publication is copyright © Edexcel Ltd 2010 . Ask The Expert can be accessed online at the following link: http://www. vocational. Through a network of UK and overseas offices.com/Aboutus/contact-us/ Alternatively. you may find our Ask The Expert email service helpful. Edexcel’s centres receive the support they need to help them deliver their education and training programmes to learners. our GCSE team on 0844 576 0027. please call our GCE line on 0844 576 0025.

i. Candidates must be rewarded for what they have shown they can do rather than penalised for omissions. but this does not preclude others. the team leader must be consulted. with accurate use of spelling. Crossed out work should be marked UNLESS the candidate has replaced it with an alternative response. 6BI07_01 1006 . Examiners must mark the first candidate in exactly the same way as they mark the last. There is no ceiling on achievement. Examiners should always award full marks if deserved. using specialist vocabulary when appropriate. Where some judgement is required. • • • • • • Quality of Written Communication Questions which involve the writing of continuous prose will expect candidates to: • • • write legibly. mark schemes will provide the principles by which marks will be awarded and exemplification may be limited. Full marks will be awarded if the candidate has demonstrated the above abilities. Mark schemes should be applied positively.e.General Marking Guidance • • All candidates must receive the same treatment. When examiners are in doubt regarding the application of the mark scheme to a candidate’s response. Questions where QWC is likely to be particularly important are indicated (QWC) in the mark scheme. grammar and punctuation in order to make the meaning clear select and use a form and style of writing appropriate to purpose and to complex subject matter organise information clearly and coherently. Examiners should mark according to the mark scheme not according to their perception of where the grade boundaries may lie. All the marks on the mark scheme are designed to be awarded. Examiners should also be prepared to award zero marks if the candidate’s response is not worthy of credit according to the mark scheme. All marks on the mark scheme should be used appropriately. if the answer matches the mark scheme.

the crossed out work for that question or part question should be marked. If the candidate has crossed out work but written no new text.g. as discussed in the Standardisation meeting Words or phrases separated by an oblique are alternatives to each other Indicate the beginning and end of a list of alternatives (separated by obliques) where necessary to avoid confusion Words inside round brackets are to aid understanding of the marking point but are not required to award the point Words inside square brackets are instructions or guidance for examiners Consecutive error / transferred error Spelling and clarity In general. a correct statement that is contradicted by an incorrect statement in the same part of an answer gains no mark – irrelevant material should be ignored • • 6BI07_01 1006 . semi colon eq / oblique {} curly brackets () round brackets [] square brackets [CE] or [TE] Crossed out work If a candidate has crossed out an answer and written new text. Use of English is however taken into account as follows: • the spelling of technical terms must be sufficiently correct for the answer to be unambiguous e. the crossed out work can be ignored. No marks are awarded specifically for quality of language in the written papers. an error made in an early part of a question is penalised when it occurs but not subsequently. for glycogen. except for the essays in the synoptic paper.GENERAL INFORMATION The following symbols are used in the mark schemes for all questions: Symbol . ‘mytosis’ is acceptable whereas ‘meitosis’ is not candidates must make their meaning clear to the examiner to gain the mark. for mitosis.g. for amylase. The candidate is penalised once only and can gain credit in later parts of the question by correct reasoning from the earlier incorrect answer. ‘illeum’ is acceptable whereas ‘ilium’ is not e. as far as it is possible to do so. ‘glicojen’ is acceptable whereas ‘glucagen’ is not e.g. for ileum. Meaning of symbol Indicates the end of a marking point Indicates that credit should be given for other correct alternatives to a word or statement. ‘ammalase’ is acceptable whereas ‘amylose’ is not e.g.

10. 6. reference to enzyme damage to eyes . Mark max (4) Mark Question Number 1(a)(ii) Answer Allow appropriate reference to risk and method of reduction. >7-14 . respiration / breathing problems / eq . appropriate reference to linear dimension / area / no greater than 5 x 5 (cm) / not > 2mm (thickness) . use coated enzymes / eq / wear mask . wear gloves / wash with copious water / wash bench down / dry up spills . 1. 4. 5. 3. possible skin reaction to enzyme /eq . gloves / goggles as appropriate . max (4) Mark (1) Question Number 1(b)(i) Answer 236 . pH . 2. wear goggles / eq . . 3. temperature . 7.Question Number 1(a)(i) Answer 1. 8. wear plaster / gloves . 8. volume of enzymes /eq . getting enzyme into blood through cut . high level of alkali damages skin / eyes . 4. 7. 55 oC . size of film / thickness of gelatine . >=5<100 ml . 5. 9. 6. 2.

4. axes labelled with units for x axis .Question Number 1(b)(ii) Answer 1. higher concentrations. 3. 3.5% to allow better assessment of reliability . 2. 2. ref to increase in number of active sites / eq . y. above 2% concentration (or their graphs suggestion (ecf) of E. axes correct (x-[Savinase]. goes up) / eq . 3.1 ÷ time*1000) . 2. greater reliability for data at {1% / 4% / 5%} / eq . 4. correct plotting (7 points including origin) . 4. reference to wide range / variability of data . have no effect on rate / reaches plateau at 2% (or suitable from their graph) . as concentration goes up . reference to outliers / anomalies . reference to more data needed for 1. suitable line of best fit / line joining points drawn with straight edge . substrate concentration limiting / eq . max (3) Question Number 1(b)(iv) Answer 1. rate (accept in this case (ecf) / 1 ÷ (mean) time *1000. Mark (4) Mark Question Number 1(b)(iii) Answer 1. Mark max (2) 6BI07_01 1006 .

enzyme costs money . reference to (idea of) best concentration to use (ignore value) . Mark max (2) 6BI07_01 1006 . 3. reference to reduced cost effectiveness at higher concentrations .Question Number 1(b)(v) Answer 1. reference to no improvement above this concentration . 4. 2.

3. max (2) 6BI07_01 1006 . (3) Mark Question Number 2(b)(i) Answer No mark for type of visual chosen 1. any diagram which depicts (roughly) correct proportions . 3. Mark (1) Mark Question Number 2(a)(ii) Answer 1. pie has key to what segments are or directly labelled. check for credentials of contributor . funding source) . max (2) Mark Question Number 2(a)(iii) Answer 1. no does not / eq . reference to evidence of peer reviewing .g. check for any bias of sponsor (e. (but) numbers do rise (much) in 1990s / fall 1994 to 1996 . (because) numbers generally rise over time / eq . 2. 2.Question Number 2(a)(i) Answer title should refer to columns 1 and 2 . 2. reference to cross check with another source . bar / histogram has key or bars labelled on axis . 4. bar or histogram should have axes labelled / pie chart needs title and percentages in the segments . 3.

(lines 30-39) discuss (better) spending of money on this . date. date 2008 . date. need to add IUCN red list reference to book / website / address / url . IUCN leaflet . 2. author(s) . max (4) Question Number 2(d)(i) Answer 1. ® just IUCN 6. ® just Wikipedia 4. ®just IUCN 2. 7. 3. Mark (2) 6BI07_01 1006 . institution(s). as they think habitat loss is considered most important reason for species loss . Mark max (3) Mark Question Number 2(c) Answer 1. 3. reference to title of newspaper / journal with household questionnaire . date site visites . 4. 8. yes they would . 1996 . majority would NOT agree with points made in these lines about hunting (accept converse answer) . 5. about possible uses of money in conservation of different types / eq . Economic . 2. some detail included. Wikipedia article url / address / title of article .Question Number 2(b)(ii) Answer 1.

Mark max (3) 6BI07_01 1006 . dubious medications. 4. 11. as only place organisms can properly exist . correct reference to appropriate habitat . lines 49-54 . teaching. lines 38-39 . as (d)(i)) First mark for implication and line reference Next two marks for reasons e. 9. 3. 12. 6. awareness . 1. environmental. 8. ethics of keeping animals in zoos .g. social. ethical. part of this (social) is education . lines 30-31 . lines 47-48 . 2.Question Number 2(d)(ii) Answer (Cannot have same ref. (wrong if) for ornaments. 5. ethical. 7. 10. ethics of hunting animals . cage environment . trophies etc / might lead to extinction .

Further copies of this publication are available from Edexcel Publications.edexcel.4496750 Registered Office: One90 High Holborn. Registered in England and Wales no. Adamsway. Notts. Mansfield. London.com Order Code US023567 Summer 2010 For more information on Edexcel qualifications. WC1V 7BH 6BI07_01 1006 . NG18 4FN Telephone 01623 467467 Fax 01623 450481 Email publications@linneydirect. please visit www.com/quals Edexcel Limited.

Mark Scheme (Results) June 2010 GCE GCE Biology (6BI04/01) Edexcel Limited. 4496750 Registered Office: One90 High Holborn. London WC1V 7BH . Registered in England and Wales No.

Ask The Expert can be accessed online at the following link: http://www. please call our GCE line on 0844 576 0025. If you have any subject specific questions about the content of this Mark Scheme that require the help of a subject specialist. our GCSE team on 0844 576 0027. For further information.Edexcel is one of the leading examining and awarding bodies in the UK and throughout the world.edexcel. occupational and specific programmes for employers.com/Aboutus/contact-us/ Alternatively.edexcel. We provide a wide range of qualifications including academic. Edexcel’s centres receive the support they need to help them deliver their education and training programmes to learners. vocational. you may find our Ask The Expert email service helpful. Through a network of UK and overseas offices.com. or visit our website at www. you can speak directly to a subject specialist at Edexcel on our dedicated Science telephone line: 0844 576 0037 Summer 2010 Publications Code UA023560 All the material in this publication is copyright © Edexcel Ltd 2010 .

Examiners should always award full marks if deserved. Examiners should mark according to the mark scheme not according to their perception of where the grade boundaries may lie. but this does not preclude others. • • • • • • Quality of Written Communication Questions which involve the writing of continuous prose will expect candidates to: • • • write legibly. i. All the marks on the mark scheme are designed to be awarded. Crossed out work should be marked UNLESS the candidate has replaced it with an alternative response. There is no ceiling on achievement. grammar and punctuation in order to make the meaning clear select and use a form and style of writing appropriate to purpose and to complex subject matter organise information clearly and coherently. the team leader must be consulted. 6BI04_01 1006 . mark schemes will provide the principles by which marks will be awarded and exemplification may be limited. Candidates must be rewarded for what they have shown they can do rather than penalised for omissions. Questions where QWC is likely to be particularly important are indicated (QWC) in the mark scheme. using specialist vocabulary when appropriate. Examiners should also be prepared to award zero marks if the candidate’s response is not worthy of credit according to the mark scheme. Where some judgement is required. Mark schemes should be applied positively.General Marking Guidance • • All candidates must receive the same treatment. if the answer matches the mark scheme. All marks on the mark scheme should be used appropriately.e. Full marks will be awarded if the candidate has demonstrated the above abilities. Examiners must mark the first candidate in exactly the same way as they mark the last. with accurate use of spelling. When examiners are in doubt regarding the application of the mark scheme to a candidate’s response.

an error made in an early part of a question is penalised when it occurs but not subsequently. as far as it is possible to do so. ‘illeum’ is acceptable whereas ‘ilium’ is not e. semi colon eq / oblique {} curly brackets () round brackets [] square brackets [CE] or [TE] Crossed out work If a candidate has crossed out an answer and written new text. Use of English is however taken into account as follows: • the spelling of technical terms must be sufficiently correct for the answer to be unambiguous e. the crossed out work can be ignored.g. for glycogen. ‘ammalase’ is acceptable whereas ‘amylose’ is not e.g. as discussed in the Standardisation meeting Words or phrases separated by an oblique are alternatives to each other Indicate the beginning and end of a list of alternatives (separated by obliques) where necessary to avoid confusion Words inside round brackets are to aid understanding of the marking point but are not required to award the point Words inside square brackets are instructions or guidance for examiners Consecutive error / transferred error Spelling and clarity In general. except for the essays in the synoptic paper. for ileum. The candidate is penalised once only and can gain credit in later parts of the question by correct reasoning from the earlier incorrect answer. the crossed out work for that question or part question should be marked. for mitosis.GENERAL INFORMATION The following symbols are used in the mark schemes for all questions: Symbol .g. ‘mytosis’ is acceptable whereas ‘meitosis’ is not candidates must make their meaning clear to the examiner to gain the mark.g. ‘glicojen’ is acceptable whereas ‘glucagen’ is not e. No marks are awarded specifically for quality of language in the written papers. for amylase. If the candidate has crossed out work but written no new text. Meaning of symbol Indicates the end of a marking point Indicates that credit should be given for other correct alternatives to a word or statement. a correct statement that is contradicted by an incorrect statement in the same part of an answer gains no mark – irrelevant material should be ignored • • 6BI04_01 1006 .

g. approx 60% readings within (+ )1 x SD / approx 90% readings within (+) 2 x SD . idea that as length of time increases. 3. {ambient / eq } temperature immersion in water age (of person at death) skin colour thickness of hair gender clothing blood loss humidity air movement {core / body} temperature at time of death . idea of more variability (in temperature) as time increases / eq .. Question Number 1(c) Answer three from the following: {(body) mass/ BMI / weight / eq} {(subcutaneous) fat /eq} surface area. 7. Idea of most readings are within {+ 1 x SD / + 2 x SD} e. use of manipulated data . 4. 2. estimate (of time of death) can only be within a {4 / 5 / 6 / 7} hour period . comment on change in reliability of time of death with time / eq . 6.Question Number 1(a) Answer cross next to degree of muscle concentration . idea of SD {measures / shows} {spread / range / eq} of data .. SD increase / eq . Mark max (4) Mark (3) 6BI04_01 1006 . Mark (2) cross next to signs of decomposition . Question Number 1(b) Answer 1. 5.

2.4 . idea of {not hitting the {chloroplast / chlorophyll}} / it is transmitted . to {incorrect / eq } {wavelength / colour / frequency} .7) . photosynthesis so more light can be used . Mark (1) Question Number 2(b)(ii) Answer Award 2 marks for correct answer (84. idea of reflection .4 – 3. 3.84) 1. correct multiplication by 100 ÷ 24. (2) [consequential errors apply] Question Number 2(b)(iii) Answer B.g. 4.Question Number 2(a) Answer 1.8 / 84. 2. Mark max (2) Question Number 2(b)(i) Answer {joules / energy} per {square metre / metre squared /(unit) area} per {year / unit time} . correct subtraction (24. reference.7 / 20. (1) Mark Mark 6BI04_01 1006 . at max. idea of light being in excess e.

in {granum / grana} . 7. 4. idea of electrons from {photolysis / eq} used to replace those lost . reference to involvement of {accessory pigments / named example} . reference to {chemiosmosis / eq} . 2. 8. 10.Question Number 2(c) [QWC] Answer (QWC – Spelling of technical terms (shown in italics) must be correct and the answer must be organised in a logical sequence) 1. 11. reference to photophosphorylation . reference to {thylakoids / thylakoid (membranes)} . 13. 5. 6. 12. reference to {synthesise ATP from ADP +P / phosphorylate ADP} . reference to ATP {synthetase / synthase / ase} . reference to electron {carrier / eq} . Mark max (6) 6BI04_01 1006 . reference to series of {redox / oxidation & reduction / eq} reactions . electrons released from {chlorophyll /photosystem / eq} / eq . reference to energy level of electrons {falls / eq} . 9. 3. (light energy) raises energy level of electrons / {chlorophyll / electrons}excited / eq .

) / 4. correct reference to denaturation of some {enzyme / protein / eq} (molecules) . reference to enzymes involved (in growth) . 8. 2.5 times}. Mark (1) Answer C. Mark (1) Answer temperature . increases by {0. rate of growth increases as temperature increases {between 13oC and 22oC / up to 22oC} .Question Number 3(a)(i) Question Number 3(a)(ii) Question Number 3(b)(i) Question Number 3(b)(ii) Answer C.) . decreases by 0.g. (therefore) rate of {growth / reactions} decreases as fewer enzyme molecules available . use of manipulated data to support above e. 5. (therefore) {enzyme and substrate (molecules) collide more / rate of enzymesubstrate complexes formation increases} as temperature increases . molecules {move about more / have more kinetic energy}.u. Mark (1) Answer 1. as temperature increases . 4. 6.1 (a. rate of growth decreases {between 22oC and 25oC / above 22oC} . Mark max (4) 6BI04_01 1006 . 3. 7.u.7 (a.

3. 5. Mark max (3) Question Number 3(b)(iv) Answer Mark 1. reference to {so light is not limiting factor / so temperature is the limiting factor}. 3. idea that (each temperature) has same light intensity . 2. (below which) no net photosynthesis takes place / eq . reference to {mineral / eq} . 4. CO2 concentration / eq . 2. photosynthesis produces {material / eq} needed for growth / eq . max (2) 6BI04_01 1006 . pH / eq (of solution) . 4. correct reference to must be above {threshold / compensation point} .Question Number 3(b)(iii) Answer 1. {wavelength / colour / frequency} of light .

(5) 6BI04_01 1006 . G = macrophage / phagocyte / eq . Mark (1) Mark (1) Answer Mark D = antigens / (glyco)proteins . E = B {lymphocytes / cells} / plasma cells . Answer A. F = antibodies / immunoglobulins . H = enzymes / lysozyme .Question Number 4(a)(i) Question Number 4(a)(ii) Question Number 4(b)(i) Answer C.

9. 2. reference to {mucus / slime} {coat /capsule} (of bacterial cells) . 7. reference to protein nature of {antigens / antibodies} . 4. antigens are specific (to each bacteria) / eq . idea that some bacteria are inside body cells .Question Number 4(b)(ii) Answer Mark 1. max (3) 6BI04_01 1006 .g. from passive immunity or breast feeding . idea that {binding / eq} can take place . 5. 6. (some bacteria) have {different / changed} antigens / eq . idea that this is a primary infection . antibodies need to be {complementary / specific} (to the antigen) . 3. 8. idea of antibodies already present e.

reference to hydrogen bonding . correct reference to {RNA-polymerase / DNA helicase} . DNA strands {separate / unzip / eq} . credit correct sequence of bases on {mRNA / DNA} . cytosine. 6. from free nucleotides / eq . 3. guanine and thymine present Nucleotides linked by phosphodiester bonds DNA only RNA only Both DNA and RNA all rows correct 2 marks two or three rows correct 1 mark Question Number 5(b)(i) 1. 7. reference to complementary base pairing . 2.Question Number 5(a) Answer Mark Description Polymer formed from a single strand of nucleotides Pentose present in the nucleotides Adenine. 4. Answer (2) Mark max (3) 6BI04_01 1006 . 5. idea that one DNA {strand / eq} used as template (to form mRNA) / eq .

3. idea that anticodon (on tRNA) {attaches / binds / lines up / eq} to the {codon / triplet} on mRNA . stop codon . 3. example quoted using the information in the diagram e. max (2) Answer max (3) Mark 6BI04_01 1006 . reference to specific amino acid attachment to tRNA . 2.g. reference to formation of peptide {bonds / links} (between adjacent amino acids) . Question Number 5(c) 1. reference to peptidyl transferase . release of the {polypeptide / ribosome} /eq . 6. used to end the {sequencing / further attachment of tRNA / eq} . 2. 5. tRNA with alanine has CGA anticodon which binds to GCU on mRNA . 4. idea that two tRNA held in ribosome (at any one time) .Question Number 5(b)(ii) Answer Mark 1.

(2) Mark Question Number 6(b)(ii) Answer 1. 3. 4.Question Number 6(a) Answer Mark 1. {variety / eq} of alleles . there will have been different mutations in each population . different alleles in each of the two {populations / eq} . 2. each {population / species} is adapted to live {in different environmental conditions / at different altitudes / eq} . 3. 2. Question Number 6(b)(i) Answer max (3) Mark 1. reference to alleles from different {species /eq } will mix / hybrids receive alleles from both { species / eq} . idea that individuals of a species can {interbreed / eq} . max (2) 6BI04_01 1006 . the {hybrids / offspring} can flower and produce viable seeds / eq . to produce fertile {offspring / eq} . 2. in a gene pool / eq .

12. reference to original population increasing in size and spreading into a wider diversity of {habitats / eq} .Question Number *6(c) QWC Answer (QWC – Spelling of technical terms must be correct and the answer must be organised in a logical sequence) 1. 7. leading to diversity in flowering times / eq . 13. reference to change in allele frequencies (over time) . restriction in gene flow / eq . 6. 10. 5. idea of plants adapted to a region . reference to survival and breeding . reference to different environmental factors in each region . each region has different selection pressures / eq . (and) other plant features / eq . 2. Mark max (6) 6BI04_01 1006 . 11. reference to mutations . between extremes of population / eq . reference to reproductive isolation . 8. 9. (leads to) differences between gene pools / eq . 4. 3.

3. max (2) Mark Question Number 7(c)(i) Answer 8 9 10 3 1 1 (1) All three answers correct to 1 significant figure . max (3) Question Number 7(b)(i) Question Number 7(b)(ii) Answer A. reference to {oxygen / carbon / methane} . texture of substratum / eq . 2. {wavelength / colour / frequency} of light . 5. 3. (this carbon dioxide is) available for photosynthesis . reference to {carbon / organic / eq} compounds in plant material . light intensity / shading . reference to woodlice {eaten / decompose} . temperature . 4. air currents / wind / eq . 4. 6. 6BI04_01 1006 . idea that digestion provides respiratory substrates .Question Number 7(a) Answer Mark 1. {pH / chemical composition / eq} of {substratum / eq} . 8. Mark (1) Answer Mark 1. 5. moisture content of {air / substratum / eq} / humidity . 2. carbon dioxide released (from respiration) . 7.

other factors need to be kept constant / eq . some might be {counted more than once / missed out} / eq . 3. 4. only one factor needs to be varied / eq . reference to {many / biotic / eq} factors (in a garden) . 2. 3. (therefore) difficult to count / eq . 2. max (3) 6BI04_01 1006 . max (2) Mark Question Number 7(c)(iii) Answer 1. for results to be (scientifically) valid . 6. 5. woodlice move about / eq .Question Number 7(c)(ii) Answer Mark 1. (these factors are) {difficult to control / eq} . reference to difficult to set test factor values .

circular loop of doublestranded DNA Name of structure Mitochondrion / mitochondria P. {cell / cell wall} bursts (easily) / eq .. during division /eq . 3. 2. Question Number 8(b)(i) Question Number 8(b)(ii) 1. max (2) Answer bactericidal . E or B E / eukaryotic Flagellum / flagella B / both plasmid P / prokaryotic (3) 1 mark for any two correct cells . (1) Answer Mark Mark 6BI04_01 1006 .Question Number 8(a) Answer Mark Description Enclosed by outer smooth membrane inner membrane folded forming cristae Long strand-like structure extending out from the cell Used for locomotion Small. cell wall {weaker /cannot form properly / eq} ..

4. idea that antibiotic no longer effective . reference to antibiotic acting as selective pressure . max (2) 6BI04_01 1006 .Question Number 8(b)(iii) Answer Mark 1. reference to some bacteria resistant (to antibiotic) . reference to some infections cannot be treated with antibiotics . idea that resistant bacteria survive and {reproduce / pass on resistance / pass on gene / eq}. 3. 2. 5.

description of how effect is assessed e. 2. 6. reference to incubation at a suitable temperature . 5.g. max (4) 6BI04_01 1006 . wells in agar . description of method used to apply different antibiotics at known positions e. 3. reference to replication (with same bacterium) . 8. measure {clear area / inhibition zone / eq} . reference to control of antibiotic concentration . 7.g.g. reference to {sterile / aseptic} technique . 4. idea of bacteria distributed evenly / description of technique e. lawn spreading .Question Number 8(c) Answer Mark 1. multidisks. reference to repetition with different bacteria .

please visit www.com Order Code UA023560 Summer 2010 For more information on Edexcel qualifications. Registered in England and Wales no. NG18 4FN Telephone 01623 467467 Fax 01623 450481 Email publications@linneydirect. Notts.Further copies of this publication are available from Edexcel Publications.4496750 Registered Office: One90 High Holborn. WC1V 7BH 6BI04_01 1006 . Adamsway. London. Mansfield.com/quals Edexcel Limited.edexcel.

4496750 Registered Office: One90 High Holborn. London WC1V 7BH .Mark Scheme (Results) June 2010 GCE GCE Biology (6BI05/01) Edexcel Limited. Registered in England and Wales No.

Edexcel’s centres receive the support they need to help them deliver their education and training programmes to learners. please call our GCE line on 0844 576 0025. our GCSE team on 0844 576 0027. We provide a wide range of qualifications including academic.edexcel. you can speak directly to a subject specialist at Edexcel on our dedicated Science telephone line: 0844 576 0037 Summer 2010 Publications Code UA023563 All the material in this publication is copyright © Edexcel Ltd 2010 .com/Aboutus/contact-us/ Alternatively. For further information. If you have any subject specific questions about the content of this Mark Scheme that require the help of a subject specialist.Edexcel is one of the leading examining and awarding bodies in the UK and throughout the world. Through a network of UK and overseas offices. you may find our Ask The Expert email service helpful. vocational.edexcel. or visit our website at www. Ask The Expert can be accessed online at the following link: http://www.com. occupational and specific programmes for employers.

Examiners should always award full marks if deserved. if the answer matches the mark scheme.General Marking Guidance • • All candidates must receive the same treatment. Mark schemes should be applied positively. All the marks on the mark scheme are designed to be awarded. but this does not preclude others. Examiners should mark according to the mark scheme not according to their perception of where the grade boundaries may lie. Questions where QWC is likely to be particularly important are indicated (QWC) in the mark scheme. Examiners should also be prepared to award zero marks if the candidate’s response is not worthy of credit according to the mark scheme. Examiners must mark the first candidate in exactly the same way as they mark the last. with accurate use of spelling. grammar and punctuation in order to make the meaning clear select and use a form and style of writing appropriate to purpose and to complex subject matter organise information clearly and coherently. • • • • • • Quality of Written Communication Questions which involve the writing of continuous prose will expect candidates to: • • • write legibly. All marks on the mark scheme should be used appropriately. When examiners are in doubt regarding the application of the mark scheme to a candidate’s response. 6BI05_01 1006 . i. Where some judgement is required. using specialist vocabulary when appropriate. Crossed out work should be marked UNLESS the candidate has replaced it with an alternative response. mark schemes will provide the principles by which marks will be awarded and exemplification may be limited. Candidates must be rewarded for what they have shown they can do rather than penalised for omissions.e. the team leader must be consulted. There is no ceiling on achievement. Full marks will be awarded if the candidate has demonstrated the above abilities.

g. semi colon eq / oblique {} curly brackets () round brackets [] square brackets [CE] or [TE] Crossed out work If a candidate has crossed out an answer and written new text. for ileum.g.g. as far as it is possible to do so. If the candidate has crossed out work but written no new text. for mitosis.GENERAL INFORMATION The following symbols are used in the mark schemes for all questions: Symbol . an error made in an early part of a question is penalised when it occurs but not subsequently. ‘mytosis’ is acceptable whereas ‘meitosis’ is not candidates must make their meaning clear to the examiner to gain the mark. as discussed in the Standardisation meeting Words or phrases separated by an oblique are alternatives to each other Indicate the beginning and end of a list of alternatives (separated by obliques) where necessary to avoid confusion Words inside round brackets are to aid understanding of the marking point but are not required to award the point Words inside square brackets are instructions or guidance for examiners Consecutive error / transferred error Spelling and clarity In general. the crossed out work can be ignored. Meaning of symbol Indicates the end of a marking point Indicates that credit should be given for other correct alternatives to a word or statement. except for the essays in the synoptic paper. ‘glicojen’ is acceptable whereas ‘glucagen’ is not e. the crossed out work for that question or part question should be marked. ‘illeum’ is acceptable whereas ‘ilium’ is not e. No marks are awarded specifically for quality of language in the written papers. a correct statement that is contradicted by an incorrect statement in the same part of an answer gains no mark – irrelevant material should be ignored • • 6BI05_01 1006 . ‘ammalase’ is acceptable whereas ‘amylose’ is not e. for glycogen. for amylase.g. Use of English is however taken into account as follows: • the spelling of technical terms must be sufficiently correct for the answer to be unambiguous e. The candidate is penalised once only and can gain credit in later parts of the question by correct reasoning from the earlier incorrect answer.

max (2) 6BI05_01 1006 . study brain activity related to {stimuli / tasks / eq} . 2. 3. {location / eq} of abnormality . different areas of brain have different functions / eq . 4. 2. 5. accessibility for surgery . 3. bleeding. {extent / size/ eq} of abnormality .g. {symptoms / eq} depend on region of brain affected / eq . ref.Question Number 1(a) Correct Answer 1.g. 3. detects level of oxygenation of the blood /measures changes in blood flow within brain / eq . (found in) different {regions / eq} of brain / eq . {increased flow / more oxygen / eq} suggests increased activity / eq . idea of different types of abnormality can cause different symptoms . to density . likely problems e. max (2) Mark Question Number 1(c) Correct Answer 1. nature of abnormality e. 4. 2. the right hand brain has {more / two/ eq} abnormalities . Mark max (2) Mark Question Number 1(b) Correct Answer 1.

. (4) 6BI05_01 1006 . .Question Number 1(d) Correct Answer Mark W Regulating core temperature Climbing stairs Regulating carbon dioxide in the blood Choosing a gift X Y Z . .

opens sodium {gates / eq} . 4. 2. 5.Question Number 2(a) Correct Answer 1. correct {reference to / description of} electrochemical gradient . Mark max (2) Mark Question Number 2(b) Correct Answer Position on diagram A D Question Number 2(c) Correct Answer Permeable to sodium ions Permeable to potassium ions . 4. reference to sodium {gates / eq} closed / eq . increased permeability (of membrane) to potassium ions / eq . correct {reference to / description of} diffusion gradient (of potassium ions) . max (3) 6BI05_01 1006 . depolarisation of adjacent {membrane / eq} / eq . (2) Mark 1. 3. 3. sodium ions move into (the neurone) . reference to potassium {gates / eq} open / eq . changes PD across membrane / eq . 2. .

3. potassium ions {move because of charge difference / eq} . PD less negative / eq 2.g. diffusion gradient balanced by potential difference . 5. 4. into {nerve cell / neurone / axon / eq} . idea that the membrane remains permeable to potassium ions . idea that potassium ion is removing a positive charge (from the outside) .Question Number 2(d) Correct Answer 1. 6. idea that equilibrium is established e. Mark max (3) 6BI05_01 1006 .

÷ 15 to give answer (2) Question Number 3(b)(ii) Correct Answer 1. allows measurement of oxygen used / eq . if incorrect allow one mark for correct working 1. affects {volume / pressure} of gas / eq .8 (mm min-1) . 12 . OR 1. OR 2. 3.Question Number 3(a) Correct Answer 1. ÷ 60 to give answer . Mark max (2) 6BI05_01 1006 . 4. no (net) change of {volume / pressure} of gas . 2. 2. 2. carbon dioxide produced in respiration / eq . reference to anaerobic respiration . no oxygen available/no oxygen uptake . carbon dioxide produced is absorbed / eq . Mark max (2) Mark Question Number 3(b)(i) Correct Answer Two marks for correct answer 0.. 3. 48 .

4. use same mass / express results per unit mass / eq . use of control with no organisms. 5. 2. temperature changes / eq . 6. 3. control temperature using a water bath / eq . pressure may affect volume of gas / eq . Mark max (4) 6BI05_01 1006 . {mass / eq} of organism may differ . at the same time / eq .Question Number 3(b)(iii) Correct Answer 1.

max (2) 6BI05_01 1006 . {increased / eq} impulses to SAN / eq . 3. 3. (starts) wave of excitation / depolarisation . Mark max (2) Mark Question Number 4(b) Correct Answer 1. (via) sympathetic {nervous system / eq } . {initiates / eq} heartbeat / eq . increases {heart rate / cardiac output} /eq . {determines / eq} heart rate . stimulates more frequent depolarisation in SAN / eq . 4. 2.Question Number 4(a) Correct Answer 1. 2.

7. 5. 8.Question Number *4(c) Correct Answer (QWC – Spelling of technical terms (shown in italics) must be correct and the answer must be organised in a logical sequence) 1. 2. 4. early depolarisation leaves ventricle insensitive . idea that peak is earlier than expected . changes {electrical activity / depolarisation} of heart / eq . peak is reversed / eq . 10. 6. missed (effective) contraction after E . reference to refractory period / eq . missed normal wave after E / longer gap before next wave / eq . idea that the wave of depolarisation is prevented . 3. no change in pressure in pulmonary artery . Mark max (5) 6BI05_01 1006 . (because) little blood in ventricles . 9.

6. gain unfair advantage / eq . other harmful substances banned / eq . drugs (in the body) can be difficult to legislate for / eq . idea that they could be used for medication . 8. 7. 4. 3. idea that (relativists) say that drugs could be used under some circumstances .Question Number 4(d) Correct Answer 1. risk to health / eq . should not allow athletes to be pressured into using drugs . burden on care services / eq . 5. idea that (absolutists) say drugs should not be used at any time . Mark max (2) 6BI05_01 1006 . 2. 9.

idea that muscles cannot extend themselves ..Question Number 5(a) Correct Answer Mark for each correct row Muscle contracted when Muscle Extensor Flexor Holding steady X X X . Lifting upwards Mark (2) Mark (1) Question Number 5(b) Question Number 5(c) Correct Answer tendons . antagonistic muscle allows control (of movement) / eq . 3. all fibres same length and width as original . Z lines closer together . Correct Answer 1. need opposing muscle to extend / eq . 2. Mark max (2) Mark Question Number 5(d) Correct Answer 1. more overlap of actin and myosin . (3) 6BI05_01 1006 . 2. 3.

5.Question Number *5(e) QWC Correct Answer (QWC – Spelling of technical terms (shown in italics) must be correct and the answer must be organised in a logical sequence) 1. ATP is required to {break cross bridges / eq} . ATP for synthesis of neurotransmitter / eq . Mark max (5) 6BI05_01 1006 . 7. 8. ATP provides energy for changing shape of myosin / eq . 6. tropomyosin moves exposing binding sites / eq . reference to {vesicles / t-tubules / sarcoplasmic reticulum} contain calcium ions . {binds / eq} to troponin . 3. needs ATP to remove calcium ions / eq . for myosin /eq . 2. 4.

5. reference to energy needed (for pump) / eq . 2.Question Number 6(a) Question Number 6(b) Correct Answer ATPase / ATP synthetase . idea that this occurs on stalked particles . 4. reference to movement of electrons along ETC /eq. ATP is formed / eq . idea that this causes an energy change or makes energy available . 4. 2. H+ ions pumped into inter membrane space / eq . (H+ ions) from reduced NAD / eq . H+ ions follow diffusion gradient / eq . 5. max (2) 6BI05_01 1006 . (ETC on) inner membrane / cristae. ATP is energy source for (biological processes) / eq . Mark max (3) Mark Question Number 6(c) Correct Answer 1. Mark (1) Correct Answer 1. 3. 3.

3. max (3) 6BI05_01 1006 . 5. 2. max (2) Mark Question Number 7(c) Correct Answer 1.. {hydrophobic / hydrophilic} interactions . 3. 2. 7. evidence from noradrenaline. gender . electrical stimulation. 4. 2. idea that enzymes are proteins . Mark max (4) Mark Question Number 7(b) Correct Answer 1. reference to {ribosome / polysomes} . can be {added to / removed from / move around in} {phospholipid bilayer / membrane} . reference to translation (of mRNA) . 8. 9. credit any two examples from the text e. 3. idea that amino acids bonded / polypeptide produced . pain killers. & 4. reference to tRNA . adrenoceptors are {proteins / glycoproteins} . multifactorial problem. reference to transcription . antidepressant drugs. adrenroceptors can interact with phospholipids e. reference to mRNA . 6.g. gene / eq . different interpretations of data / eq .Question Number 7(a) Correct Answer 1. phospholipids can move in the membrane / eq . {incomplete / insufficient} data / eq . 4. reference to genetic code / eq .g.

g. has long term side effects e. has short term side effects e. 8. very precise effects / eq . laughing. genes from different species / eq . General (Gene or light therapy) 14. 10. dangers of using virus as vector / eq . idea that it affects the whole brain . ethical issues of genetic modification / eq .g. 7. requires genetic modification / eq .Question Number *7(d)(i) Correct Answer (QWC – Spelling of technical terms (shown in italics) must be correct and the answer must be organised in a logical sequence) Drug therapy 1. 5. Mark max (7) 6BI05_01 1006 . suicidal tendencies . depression. 4. precise group of cells affected / eq . crying . has effects on {other areas of the brain / other cell types} . Gene therapy 9. corrects chemical imbalance / eq . mood swings. 6. 15. 13. targets specific area of the brain / eq . 2. invasive procedure has risk / eq . relieves tremors /eq . Light therapy 11. idea that it is difficult to get dose right . 12. DBS (Deep Brain Stimulation) 3.

max (3) Mark Question Number 7(f) Correct Answer 1. idea that genes can be incorporated into {host DNA / eq} max (3) 6BI05_01 1006 . 3. pigments (in cones) respond to {specific / eq} wavelength / eq . 2. Parkinson’s {lack / eq} of dopamine . 4. 4. binding to surface protein promotes entry to cell / eq . light affects pigments / eq . 5. 2. reference to human cold virus . rhodopsin / iodopsin (in mammals) . virus has specific surface proteins / eq . both caused by {lack / eq} of neurotransmitter . depression {lack / eq} of serotonin . virus acts as a vector .Question Number 7(d)(ii) Correct Answer 1. (changes in pigment) result in action potentials /nerve impulses / eq . 3. Mark max (2) Mark Question Number 7(e) Correct Answer 1. match surface{proteins / receptors / eq} of target cell . 6. 2. 3.

6. 2. 5. reference to histamine / mast cells . reference to temperature increase . Mark max (2) 6BI05_01 1006 . Oedema / swelling / eq .Question Number 7(g) Correct Answer 1. 7. idea that phagocytes / macrophages move to site . 4. 3. increased blood flow / eq . {causes / involved in / eq} inflammation / eq . vasodilation / eq . 8. increased {permeability / leakage} of blood vessels .

tissue culture .g. 9. reference to other models e. representative sample / eq . Mark max (4) 6BI05_01 1006 . 8. 3. 10. objective measurement of effects / eq . socioeconomic. appropriate comment on safety issues e. hormone levels in females.g. long term data . 6. other factors need to be {controlled / measured} e. consideration of time e. double blind testing . between dose and observation. 2. reference to placebo .g.g. (sufficiently) large sample / eq . 5. 7. nutrition . toxicity .Question Number 7(h) Correct Answer 1. 4. animals. (collecting / analysing) separate data sets for males and female / eq .

com Order Code UA023563 Summer 2010 For more information on Edexcel qualifications. London. WC1V 7BH 6BI05_01 1006 . Registered in England and Wales no.edexcel.Further copies of this publication are available from Edexcel Publications. please visit www. NG18 4FN Telephone 01623 467467 Fax 01623 450481 Email publications@linneydirect. Notts. Mansfield.4496750 Registered Office: One90 High Holborn. Adamsway.com/quals Edexcel Limited.

Mark Scheme (Results) June 2010 GCE GCE Biology (6BI08/01) Edexcel Limited. London WC1V 7BH . 4496750 Registered Office: One90 High Holborn. Registered in England and Wales No.

edexcel. please call our GCE line on 0844 576 0025. you can speak directly to a subject specialist at Edexcel on our dedicated Science telephone line: 0844 576 0037 Summer 2010 Publications Code UA023570 All the material in this publication is copyright © Edexcel Ltd 2010 6BI08_01 1006 . or visit our website at www.com. We provide a wide range of qualifications including academic. Ask The Expert can be accessed online at the following link: http://www.edexcel. If you have any subject specific questions about the content of this Mark Scheme that require the help of a subject specialist.com/Aboutus/contact-us/ Alternatively.Edexcel is one of the leading examining and awarding bodies in the UK and throughout the world. For further information. you may find our Ask The Expert email service helpful. vocational. occupational and specific programmes for employers. Through a network of UK and overseas offices. our GCSE team on 0844 576 0027. Edexcel’s centres receive the support they need to help them deliver their education and training programmes to learners.

Examiners should always award full marks if deserved. the team leader must be consulted. All marks on the mark scheme should be used appropriately. Crossed out work should be marked UNLESS the candidate has replaced it with an alternative response. i.e. When examiners are in doubt regarding the application of the mark scheme to a candidate’s response.General Marking Guidance • • All candidates must receive the same treatment. mark schemes will provide the principles by which marks will be awarded and exemplification may be limited. 6BI08_01 1006 . Where some judgement is required. but this does not preclude others. All the marks on the mark scheme are designed to be awarded. with accurate use of spelling. Mark schemes should be applied positively. Candidates must be rewarded for what they have shown they can do rather than penalised for omissions. using specialist vocabulary when appropriate. • • • • • • Quality of Written Communication Questions which involve the writing of continuous prose will expect candidates to: • • • write legibly. Examiners must mark the first candidate in exactly the same way as they mark the last. There is no ceiling on achievement. Full marks will be awarded if the candidate has demonstrated the above abilities. grammar and punctuation in order to make the meaning clear select and use a form and style of writing appropriate to purpose and to complex subject matter organise information clearly and coherently. if the answer matches the mark scheme. Examiners should mark according to the mark scheme not according to their perception of where the grade boundaries may lie. Questions where QWC is likely to be particularly important are indicated (QWC) in the mark scheme. Examiners should also be prepared to award zero marks if the candidate’s response is not worthy of credit according to the mark scheme.

The candidate is penalised once only and can gain credit in later parts of the question by correct reasoning from the earlier incorrect answer. the crossed out work for that question or part question should be marked. Use of English is however taken into account as follows: • the spelling of technical terms must be sufficiently correct for the answer to be unambiguous e. ‘mytosis’ is acceptable whereas ‘meitosis’ is not candidates must make their meaning clear to the examiner to gain the mark. except for the essays in the synoptic paper. as discussed in the Standardisation meeting Words or phrases separated by an oblique are alternatives to each other Indicate the beginning and end of a list of alternatives (separated by obliques) where necessary to avoid confusion Words inside round brackets are to aid understanding of the marking point but are not required to award the point Words inside square brackets are instructions or guidance for examiners Consecutive error / transferred error Spelling and clarity In general. ‘illeum’ is acceptable whereas ‘ilium’ is not e.g. for ileum. semi colon eq / oblique {} curly brackets () round brackets [] square brackets [CE] or [TE] Crossed out work If a candidate has crossed out an answer and written new text. an error made in an early part of a question is penalised when it occurs but not subsequently. as far as it is possible to do so.GENERAL INFORMATION The following symbols are used in the mark schemes for all questions: Symbol . If the candidate has crossed out work but written no new text. Meaning of symbol Indicates the end of a marking point Indicates that credit should be given for other correct alternatives to a word or statement. for mitosis.g. for amylase. for glycogen.g. a correct statement that is contradicted by an incorrect statement in the same part of an answer gains no mark – irrelevant material should be ignored • • 6BI08_01 1006 .g. ‘glicojen’ is acceptable whereas ‘glucagen’ is not e. the crossed out work can be ignored. ‘ammalase’ is acceptable whereas ‘amylose’ is not e. No marks are awarded specifically for quality of language in the written papers.

g. reference to which part of the membrane affected e.g. suitable trend suggested for stated factor e. {phospholipids / proteins} . 2.g. explanation of how membrane component affected e. 4. reference to effect on the permeability of the membrane (of cell or vacuole) . 5. 3. Mark (2) Mark Question Number 1(a)(ii) Answer 1.{ movement or solubility of phospholipids / denaturation of protein} / eq . increasing temperature has {no / little effect} at low temperature but a greater effect at high temperature / increasing alcohol concentration increases permeability . Hypothesis hypothesis must be testable . max (3) 6BI08_01 1006 .g. reference to {betalain / pigment / red colour} leaking from the {cells / vacuoles} . temperature /age / storage / duration / prior treatment with solvent / pH / bile salts /eq .Question Number 1(a)(i) Answer Factor suitable factor stated e.

time spent in {solution / water / tube / eq} . suitable control method described e. pH . 2. {type / source / variety / eq} of beetroot used. reference to measuring colour of solution . 6. appropriate method of reducing error described e.Question Number 1(b)(i) Answer 1.g increased temperature increases leakage of pigment / eq . temperature by using a water bath / eq . 7. 2. volume of water used / eq . 5. Mark max (2) Question Number 1(b)(ii) Answer Factor controlled 1. Mark (2) 6BI08_01 1006 . {volume / mass / surface area} of beetroot (cylinders) used / eq . Description of effect 2. 4. Mark (2) Question Number 1(c) Answer 1.g.g. any other suitable variable . use of suitable reference {cuvette / solution} / reference to calibration / reference to suitable filter used / eq . age of beetroot / eq. description of likely effect on the dependent variable provided e. 3.

4 Mark (1) Mark Question Number 2(b) Athlete A B C D E F G H I (4) Question Number 2(c) Answer 1.5 0. differences include suitable – sign for A and I . athlete A / C / I .4 5.1 -0.2 5.9 -0.8 5.3 0. Mark (2) 6BI08_01 1006 .0 4.3 5. Number of red blood cells (x1012)per dm3 Difference after before mountain mountain training training 5.6 0. 2.4 0.1 5.2 5.Question Number 2(a) Answer there will be no significant difference in the number of red blood cells in the blood of the athletes before and after the mountain training / eq .6 0.8 5. correct column headings with units .7 0. all differences calculated correctly . for {A / I} red blood cell count decreased (after mountain training) / for C increase greater than others / eq .0 5.9 5. 2.1 5.3 0.5 5.4 4.5 5.5 5. 3.1 5. suitable table format . 4.2 4. Answer 1.

Question Number 2(d)

Answer 1. {5.1 / 5.12} x1012 / eq ; 2. {5.4 / 5.38} x1012 / eq ;

Mark

(2) Question Number 2(e) Answer A axes correct orientation and scale with units and labels ; F data plotted as bar chart ; P bars plotted correctly ; B range bar included ; Question Number 2(f) Answer 1. the value of t is greater than {critical value / 2.12} / eq ; 2. at the 95% confidence level /reference to probability 0.05 / significance {5% /0.05} / eq ; 3. therefore there is an increase in the number of red blood cells (per dm3 of blood) in the athletes after (2 weeks of mountain) training / eq ; (3) Mark Mark

max (3)

6BI08_01 1006

Question Number 3(a)

Answer 1. reference to an appropriate sampling technique e.g. need some form of systematic sampling to provide a suitable range of distances seeds are placed apart from each other ; 2. & 3 . credit any two appropriate safety issue e.g. suitable reference to lack of danger, consideration as to whether parsnip seeds are poisonous, reference to dangerous animals, washing hands ; ; 4. reference to an appropriate ethical issue e.g. lack of ethical considerations in growing parsnip seedlings ;

Mark

max (3) Mark

Question Number 3(b)

Answer 1. practice method / see if method will work / eq ; 2. check most suitable {conditions / seasons / eq} for {growth/ germination} (of parsnip seeds) ; 3. select suitable timescale (for measuring germination / growth rates) / eq ; 4. identify other variables that may need to be taken into account / eq ; 5. reference to use same {source / variety} of parsnip seeds ; 6. to determine appropriate dependent variable / eq ;

max (4)

6BI08_01 1006

Question Number 3 (c)

Answer 1. clear statement of dependent variable i.e. exactly what is to be measured stated (percentage / eq} of seeds germinated / mass of {parsnips / eq) ; 2. measurement method described ; 3. clear statement of a suitable independent variable e.g. sowing density ; 4. {distances apart / densities} for parsnip seeds suggested ; 5. reference to consideration of source of the parsnip seeds (to reduce variation) ; 6. suitable medium for germination of seeds suggested (compost / moist cotton wool / plant tissue culture / eq) ; 7. some clear consideration of time period over which the seeds will be {measured / allowed to germinate / eq} ; 8. identification of one other variable that could affect growth / germination ; 9. description of how this variable can be controlled ; 10. identification of a second variable that could affect growth / germination ; 11. description of how second variable can be controlled ; 12. clear reference to need for repeats ;

Mark

(8) + (2) QWC

6BI08_01 1006

2. statistical test appropriate to data e. 4. The account is written in continuous prose which is grammatically sound with no major spelling errors. Level 2 1 Level 3 2 Question Number 3(d) Answer 1. Some relevant scientific vocabulary is used. There is good use of scientific vocabulary in the context of the investigation described. Scientific vocabulary is very limited with many spelling and grammatical errors. The account is well organised with no undue repetition and a correct sequence. Mark max (4) 6BI08_01 1006 .test/ Mann-Whitney U test/ Chi – squared / eq} . reference to means calculated from repeat data . clear table which matches method description with headings and units . statistical test justified /eq . 5. There is some disorganisation in the account which is not always in the correct sequence. The account is not always in continuous prose and there are grammatical errors and some important spelling mistakes. use of {Spearman’s Rank / eq} for correlation / suitable test to compare numbers germinated {t. graph format appropriate to data .QWC award up to 2 marks level Mark Descriptor Level 1 0 The account is very disorganised and is very difficult to follow.g. 3.

max (3) 6BI08_01 1006 . difficult to control all factors (affecting yield) / eq . 4. any other appropriate limitation . 5. measuring {germination / eq} does not necessarily correspond to yield of crop / eq . 3. 2. 6.Question Number 3(e) Answer Mark 1. {controlled / experimental / eq} conditions may not represent natural growing conditions / eq . impossible to control natural variation of seeds / genetic factors / eq . timing of germination may be erratic / eq .

Notts.4496750 Registered Office: One90 High Holborn. Mansfield.Further copies of this publication are available from Edexcel Publications.com Order Code UA023570 Summer 2010 For more information on Edexcel qualifications. NG18 4FN Telephone 01623 467467 Fax 01623 450481 Email publications@linneydirect. WC1V 7BH 6BI08_01 1006 . London. Registered in England and Wales no. please visit www.com/quals Edexcel Limited.edexcel. Adamsway.

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