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2010 First Aid for the USMLE

Bonus Microbiology material


HIV-positive adult
Neoplasm/mucosa Hairy leukoplakia Often on lateral tongue EBV
Non-Hodgkin’s Often on oropharynx EBV
Lymphoma (Large (Waldeyer’s ring)
cell type)
Squamous cell Often in anus (gay male) HPV
carcinoma or cervix (female)
“Fluffy,” white, Often on buccal mucosa Candida albicans
cottage-cheese
lesions
Skin Superficial vascular Biopsy reveals Bartonella henselae—
proliferation neutrophilic inflammationcauses bacillary
angiomatosis
Superficial, Biopsy reveals HHV-8—causes
neoplastic vascular lymphocytic inflammation Kaposi sarcoma
proliferation
Systemic Low-grade fevers, Oval yeast cells within Histoplasma
cough, macrophages capsulatum—causes
hepatosplenomegaly only pulmonary
symptoms in
immunocompetent
hosts
CNS Retinitis - CMV
Meningitis India ink stain reveals Cryptococcus
narrow-based budding (do neoformans (may also
not confuse with broad- cause encephalitis)
based budding of
Blastomyces)
Abscess? Many ring-enhancing Toxoplasma gondii
lesions on imaging
Respiratory Invasive Aspergillus fumigatus
aspergillosis
Pneumonia Especially when CD4 < Pneumocystis jiroveci
200 cells/mm3
Tuberculosis-like Especially when CD4 < Mycobacterium
disease 50 cells/mm3 avium-intracellulare
Interstitial Biopsy reveals cells with CMV
pneumonia intranuclear and
cytoplasmic inclusion
bodies