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PREDISPOSING FACTORS PRECIPITATING FACTORS
AGE: >50 years old
Family History of Liver Cancer
Inflammatory Bowel Disease
DIET: low residue, high fat, highly refined, low fiber
Growth of adenomatous polyps (adenomas)
the polyps grow slowly, and most take 5 to 10 years or longer to be malignant
malignant polyps the
diminished immune response
lack of reaction by the body's defense mechanisms to foreign substances
malignant polyps begin to invade the bowel wall
invasion of gram negative bacteria to the bloodstream
tumors in the right intestine
necrosis and ulceration sepsis malignant bowel tumors spread by: lymphatic and hematogenous channels direct extension to nearby organs
interact with white blood cells and blood vessel walls detachment of cancer cells from the primary tumor spread of cancer cells into the blood stream microorganisms is able to replicate and overwhelm host defenses inflammatory response altered lung functions lung metastasis establishment of blood sup sites (angiogen Ineffective Airway Clearance liver metastasis edema of alveolar membrane lungs were filled with exudates due to inflammation gases cannot pass through edematous membrane air cannot enter fluid filled alveoli Risk for Ineffective Tissue Perfusion anorexia altered protein metabolism Impaired Gas Exchange weight loss impaired gas diffusion Ineffective Breathing Pattern Risk for Imbalanced Nutrition: Less than Body Requirement .
ATING FACTORS Sedentary Lifestyle malignant polyps increases in size within the lumen gin to invade the wall tumors in the left intestine ulceration of the blood supply wel tumors by: seeding of. or implanting of cells into the peritoneal cavity .
establishment of cancer cells to secondary sites lungs liver blishment of blood supply to secondary sites (angiogenesis) liver metastasis altered protein metabolism weakness an Impaired Physical Mobility Risk for Impaired Skin Integrity .