DRUG STUDY Generic & Brand Name Generic: Cefuroxime Dose, strength & formulation Ordered: CEFUROXIME 250mg IVTT q8hrs

Timing: q8 hrs. Duration: immediate. Other Form: Classification: Second generation cephalosporin, antibiotic Suspension: 125mg/5ml, 250 mg/5 ml Infusion ; 750 mg, 1.5 premixed, frozen solution Injection: 750 mg, 1.5. mg Capsules; 50 mg, 100 mg, 200 mg, 400 mg: Indication/Mechanism of Action Indication: -Serious lower respiratory tract infection, UTI, skin or skin structure infections, bone/ joint infection, septicemia meningitis and gonorrhea. -Perioperative prevention - Bacterial exacerbations of chronic bronchitis/ secondary bacterial infection of acute bronchitis -Acute bacterial maxillary sinusitis -Pharyngitis & tonsilities -Otits media -Uncomplicated skin & skin-structure infection -Uncomplicated UTI -Uncomplicated gonorrhea -Early lyme disease -Impetigo Adverse/side effects drug Interaction Side Effects: CNS: dizziness, headache, insomnia, stroke CV: hypertension, MI, peripheral edema EENT: Pharyngitis, rhinitis, sinusitis GI: Abdominal pain, diarrhea, dyspepsia, flatulence, nausea, GI bleeding METABOLIC: Hyperchloremia, hypophosphatemia MUSCULOSKETETA L: Back pain RESPIRATORY: Upper respiratory tract infection SKIN: Erythema, multiforme, exfoliative dermatitis, rash, Stevens- Johnson syndrome, toxic epidermal necrolysis OTHER: Accidental injury INTERACTIONS Drug-drug Diuretics ; may increase risk of adverse renal -If GI reactions occur,monitor patient’s hydration. Nursing Responsibility Rationale Client Teaching

-Assess patient’s infection before therapy and regularly thereafter. -Before giving the first dose, obtain specimen for culture and sensitivity test. -Before giving first dose, ask patient about previous reactions to cephalosporin and penicillin. -Be alert for adverse reaction and drug interaction.

-To monitor drug’s effectiveness.

• Advise patient to take oral suspension with food to enhance absorption. • Tell patient to report adverse reactions. • Instruct patient to take drug exactly as prescribed, even he feels better after • Stress the importance of taking the drug.

Brand: Ceftin

-To ensure right drug.

-to avoid cross sensitivity with other betalactamantibiotics

• Maintain all of the usual activities and restrictions that apply to your condition

MECHANISM OF ACTION; Chemical effect: May selectively inhibit COX 2 decreasing prostaglandin synthesis Therapeutic effect;

-To establish proper precautionary measures and management for possible adverse effects of the drug. -To prevent dehydration .

-Before giving the first dose. Drug-food: Any food: May increase drug adsorption & bioavailability of suspension. obtain specimen for culture & sensitivity tests. Sometimes used for this effect. Give suspension with food. ask the pt. reactions . Monitor renal function closely. about previous reactions to. Tablets may begin without regard to food.Relieves pain & inflammation in joints and smooth muscle tissue. Begin therapy pending test results. Probenecid: may inhibit excretion & increase level of cefuroxime. . -Before giving dose.

-Assess pt. depression. GI condition before starting therapy and Regularly thereafter to monitor drug’s effectiveness .To check the patient and the Family’s level of understanding about the drug. dry mouth.DRUG STUDY Generic & Brand Name Generic: Ranitidine Brand: Zantac Classification: Pharmacologic class: H2 –receptor antagonist Therapeutic class: Antiulcerative Timing: q8 Duration: 50 mg slow IVTT -Intractable duodenal ulcer. -to monitor the drug effectiveness. Dose. -CV: CHF. -Duodenal and gastric ulcer -Maintenance therapy for duodenal ulcer -Gastroesophageal -Reflux disease -Erosive esophagitis -Self-medication for occasional heartburn. -GI: Nausea. -encourage patient to have a regular check up. ataxia. irritability. *Be alert for adverse reactions and drug inter action. -acid indigestion and sour stomach Mechanism of action: Inhibits the action of the histamine at H2 receptor site located primarily in gastric parietal cells. orthostatic hypotension.anorexia. -encourage patient to increase oral fluid intake and fibers to prevent or minimize constipation. -GU: Urinary retention -assess patient for epigastric or abdominal pain and frank or occult blood in the stool. dyspnea. *asses patient’s and family’s knowledge of drug therapy. CNS: Light headedness. -inform patient that this medication can cause temporary grey black color of tongue and stool. . strength & formulation Ordered: Indication/Mechanism of Action Indications: Adverse/side effects drug Interaction Adverse reaction: Nursing Responsibility Assessment: Rationale Client Teaching -instruct to report any adverse reaction occurs.’s.psychosis. pathologic hypersecretory conditions. dizziness. emesis or gastric aspirate. confusion. constipation. -to establish proper precautionary measures and management for possible adverse effects of the drug. . in resulting in inhibition of gastric acid secretion. -to take an early actions of signs of internalbleeding. hallucination. -Do not discontinue abruptly when treating parkinsonism syndrome.5 mg TIV q 12 hrs -it might cause other complications. ther forms: O 12. -inform patient that drug can cause drowsiness and dizziness. parkinsonian crisis may occur. insomnia.

Dose. Bisacodyl works by stimulating enteric nerves to cause colonic mass movements. avoid use together -Assess for baseline data -to establish proper precautionary measures and management for possible adverse effects of the drug.213) Bloating. >Teach patient about dietary sources of fiber. -Auscultate bowel sounds at least once per shift. May cause gastric irritation or dyspnea from premature dissolution of enteric coating. -To prepare the patient for any side effect.Obtain history of bowel disorder. It is also a contact laxative. including bran and other cereals use of drugs. nutritional status. >Advise patient to report adverse effects to prescriber. >teach patient the proper storage of the medication. . >Warn patient against excessive use of drugs. nausea. . -Check for pain and cramping and to know the condition of the patient >.DRUG STUDY Generic & Brand Name Generic: Bisacodyl Dulcolax rectal suppository 10 mg adult. fluid intake. cramps. 2 suppositories per rectum Timing: HS(8pm) Duration: Other forms: Enema: 10mg/30 ml Tablet(delayedrelease): 10 mg Tablets(entericcoated Chronic constipation. GI status. preparation for surgery/rectal/bowel examination Mechanism of action: . exercise habits & normal patterns of eliminations. it increases fluid and NaCl secretion (lippicott & wilkins 2009 Ed. -Be alert for adverse reactions and drug inter action -.Advise patient to swallow enteric-coated tablet whole to avoid GI irritation. or discomfort. faintness.By checking frequency & characteristic of stools.. strength & formulation Ordered:] Indication/Mechanis m of Action Indications: Adverse/side effects drug Interaction Adverse reaction: Nursing Responsibility Assessment: Rationale Client Teaching Brand: dulcolax Classification: Stimulant laxative Drug interactions: . rectal irritation. --to indicate baseline data and monitor drug’s effectiveness. vomiting. stomach fullness. -.

*Take drug as prescribed by the physician. antiinflamm atory . *Teach patient to recognize and immediately report signs and symptoms of GI bleeding. Mechanism of Action: *May inhibit prostaglandin synthesis *Relieves pain and inflammation CV:edema.4% . -To monitor drug’s effectiveness. -To minimize local effects. List all the medication the patient is taking. Be alert for adverse reactions and drug interactions. *Advise patient to report persistent or worsening pain. Drug may cause peptic ulcers. polyuria. Injection:15 mg/ml. GI bleeding. hypertension. 0. palpitations EENT:transient stinging and burning GI:diarrhea. STRENGTH & FORMULATIO N INDICATION/ MECHANISM OF DRUG ACTION ADVERSE/SIDE EFFECTS DRUG INTERACTION NURSING RESPONSIBILITIES RATIONALE CLIENT TEACHING Generic: Ketorolac Tromethamine Ordered: Indications: >Short-term management of pain Adverse/Side Effects: CNS:dizziness.5% Tablets:10 mg -To prevent drug interaction. eosinophilia. renal failure Hematologic: anemia. Timing: Brand: Duration: 6-8 hours Available Forms: Classification: • • insomnia. 4. drowsiness. Planning & Implementation: 3. -Monitor patient closely. or perforation of the stomach and intestine. NSAID Analgesi cs. dyspepsia. 5. Assessment: 1. Apply pressure to injection site for 15-30 seconds after injection. GI pain.DRUG STUDY GENERIC/BRA ND NAME & CLASSIFICATI ON DOSE.30 mg/ml Opthalmic Solution:0. Assess patient’s pain before and after drug therapy. *Explain that drug is intended only for short term use. nausea GU:hematuria. purpura 2. -To avoid severe adverse effects. *Tell patient not to exceed to the prescribed amount. headache.

Antihypertensive. Warfarin:May increase levels of free salicylates or warfarin in blood. diuretics:May decrease effectiveness of these drugs.Skin:sweating Other:pain at injection site. Drug Interaction: Drug-Drug. Methotrexate: May decrease methotrexate clearance and increase toxicity. . Monitor reactions closely. Lithium:May increase lithium level.

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