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Emerita, C. Simeon, Miko Adrian G. Besañes, Jamille Elizabeth D.L. Mabalo,

William Regil C. Paraiso, and Robyn C. Sagum.
Department of Biological Sciences, College of Science, University of Santo Tomas, Manila 1015

Medicinal plants play an important role in the management of diseases especially in developing
countries. Artemisia species are widely used in Asia to treat various diseases. This study was
undertaken to evaluate the anti-hyperglycemic activity of alkaloid rich extract of Artemisia
vulgaris leaves. Alkaloids from the crude extract were isolated by liquid-liquid extraction and
administered orally (50 mg/kg, 100 mg/kg and 200 mg/kg body weight) in Streptozotocin-
induced diabetic mice. After 3 weeks of treatment, results showed that those treated with the
concentration of 200 mg/kg BW of the plant extract, had a significant decrease in the blood
glucose level of mice. This result indicates anti-hyperglycemic activity of the plant on male ICR