CELL COMMUNICATION

PRESENTED BY: SIDHARTH GANDHI 10001510014 & SHASHANK SHEKHAR SINGH 10001510013

Slide 1 SG1 Sidharth Gandhi. 3/23/2011 .

so as to transfer the information's between themselves with the help of signal pathways so as to accomplish various biological processes.Definition: y Cell communication is the process by which various cells work together and coordinate. .

IMPORTANCE OF CELL SIGNALLING It affects every aspect of cell structure and function. y The combined effects of multiple signals determine cell response. y . y Cell-to-cell communication is essential for multi-cellular organisms.

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CELL SIGNALLING AND MECHANISM: StepStep-1 Release of ´Extra Cellular Messenger Moleculeµ. .

.StepStep-2 Binding of the messenger molecule by the ´receptorsµ on the extra cellular surface . and relaying of the signal through the receptor cytoplasmic domain.

Types of Receptors .

Fig. 11-6-3 StepStep-3 Transmitting of signal into the cell interior. EXTRACELLULAR FLUID CYTOPLASM Plasma membrane 2 Transduction 3 Response 1 Reception Receptor Activation of cellular response Relay molecules in a signal transduction pathway Signaling molecule .

.StepStep-4 Reaching of transmitted signal through signaling pathways to the target proteins.

. 4) Death of the cell . 2) Increase or decrease of cell mobility. 3) Activation of DNA synthesis.StepStep-5 Accomplishment of cellular process which can be:1) Change in gene expression.

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.Definition of Signal Transduction It is the overall process in which the information which is carried by the extracellular messenger molecule is translated in to the changes that occur inside a cell .is referred as signal transduction.

Overall process .

y Ligand gated channels. y Steroid hormone receptors. y .Types of Receptors G-protein coupled receptors. y B & T cell receptors. y Receptor protein tyrosine kinases.

G-Protein-Linked Receptors Protein- .

Ion-ChannelIon-Channel-Linked Receptors .

y Any Questions???? .

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