Treatment
of
ocular
surface
neoplasm’s
per
BCSC
volume
8
Cornea
and
External
Dz.
 Benign
 Conjunctival
Papilloma
 Small
pedunculated
papilloma:
observe
–
 spontaneous
resolution.

Oral
cimetidine
 is
immunomodulator.




 Sessile
limbal
papilloma
–
obs
closely
or
 excise
with
cryotherapy
 
 Limbal
dermoid
 Obs
or
shave.

Relaxing
incsion
or
LK.
 Preinvasive
 Conjunctival
intraepithelial
neoplasia
 Excise
with
1‐2
mm
clear
margins
 (CIN)
 Corneal
intraepithelial
neoplasia
 Scrape
opalescent
epithelium
from
 underlying
Bowman’s
layer,
or
observe.

 Don’t
disturb
Bowman’s
layer.

 Cryotherapy,
alcohol
to
adjacent
cornea
 and
sclera.


 Malignant
 Squamous
Cell
Carcinoma
 Excise
with
4mm
margins.

Treat
sclera
 with
absolute
EtOH.

Cryo
to
conj
 margins.


 Mucoepidermoid
Carcinoma
 Wide
surgical
excision,
cryo
and
radiothx
 Sebacious
cell
adenocarcinoma
 Full
thickness,
map
biopsies.

Wide
 excision/exenteration
with
tumor
free
 margins.

Radiotherapy.

Sentinal
LN
 biopsy.


 Melanoma
 Excisional
biopsy.

Excise
conj
4mm
 beyond
tumor
margins.

Exenteration
for
 advanced
dz.


 Kaposi’s
Sarcoma
 Debulking,
cryothx,
radiothx,
chemo.

 Intralesional
interferon
alpha‐2a
 Lymphoid
hyperplasia
 Obs
or
local
exision.

Refer
for
gen
med
 consultation.
 Lymphoma
 Refer
to
oncology.

Incisional
biopsy.

 Systemic
chemo,
local
radiation.


 


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