Patient¶s Name: Salada, Honelyn Age: 31 years old Sex: Female Admitting Diagnosis: Urinary Tract Infection Attending

Physician: Dr. HilarionHeramil, MD Admission Date/Time: January 26, 2011 4:30pm Vital Signs: BP: 130/80 Temp: 37°C Chief Complaint: Date Ordered: Dysuria, lumbar pain January 26, 2011 Doctor¶s Order:Ampicillin 1g vial q6° IVTT, (-) ANST

Generic Name

Ampicillin Sodium

Brand Name

Ampisan

Functional Classification

Systemic Anti-infectives

Chemical Classification

Penicillins

Indication

Treatment of UTI, otitis media, sinusitis, bronchitis, uncomplicated community-acquired pneumonia, Haemophilusinfluenzae infections and invasive salmonellosis.

Contraindication

Hypersensitivity to penicillins. Infectious mononucleosis. Use cautiously with renal disorders.

Diarrhea. and pseudomembranous colitis. Route Onset Peak Duration I. thus inhibiting cell wall biosynthesis. cloxacillin or flucloxacillin and aminoglycosides. 1 gram vial will be diluted in 7. nausea and vomiting.Mode of Action Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin binding proteins (PBPs). Ideal Dosage Preparation and Supply Form IVAdult Usual Dose: 1-2 gramsevery 4-6 hours in slow intravenous injection over 10-15 minutes. which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested. Skin rash increased with allopurinol. Probenecidincreases blood levels. Simultaneous use with oral contraceptives may Drug Interaction lead to increased risk of breakthrough bleeding and reduced efficacy of the contraceptive. Immediate 5 min 6-8 hr Adverse Effect Skin rashes including urticaria or maculopapular rash. clavulanic acid or sulbactam.4ml of distilled or bacteriostatic water to have a 135/ml concentration and 2 gram vial with 14. .V.8ml distilled water for 135/ml concentration. penicillinase-stable drugs eg. Synergism with -lactamase inhibitors.

Change I. For direct I. liver and renal function tests.V. Assessment Nursing Responsibilities . 7. Watch for signs and symptoms of hypersensitivity reaction. B. 4. serum electrolytes. renal disorders . cephalosporins. Monitor for bleeding tendency or hemorrhage. 2. A. Respiratory.Potentially Fatal: Increases disulfiram and anticoagulant effects.15 minutes. Ampicillin is a broad spectrum antibiotic which is Rationale for Giving the Medication active against Gram-positive and Gram-negative bacteria. urinalysis. adventitious sounds. site every 48 hours. It is given to kill a wide range of bacteria since no culture was done to identify the specific bacteria causing the infection. skin color.V. lesion. Don¶t exceed 200 mg/minute. bowel sounds.More rapid administration may result in convulsive seizures. or other allergens.Physical: Culture infected area. 3. 5. Interventions 1. Monitor patient¶s vital signs to serve as baseline data and to determine the effectiveness of the drug. injection. Observe patients ¶10 rights¶ in drug administration.History: Allergies to penicillins. give over 10 . treating the underlying cause of the disease (UTI) will alleviate its symptoms including dysuria and lumbar pain. Thus. . 6. hematocrit. Check IV site carefully for signs of thrombosis or drug reaction.

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