Pharmaceutical Study of Pottali Kaplana

Vd.V.Ramakrishna
Ayurved Vachaspati

Works Manager, Annapurna Bio-Ved(p) Ltd., Injapur Village, R.R.Dist, A.P

Pottali Rasayana ‡ Rasashastra dosage forms ‡ Pharmaceutics
‡ Pharmaceutics is the discipline of pharmacy which deals with all facets of the process of turning a new chemical entity (NCE) into a medication able to be safely and effectively used by patients in the community. Pharmaceutics is the science of dosage form design. ‡ ‡ ‡ ‡ Khaeraleeya Kupipakva Pottali A drug dosage form intended to be in small dose, quick to act, tasteless, and acts irrespective of prakriti, kala, and effective to manage the morbidity

Pottali kalpana
‡ 1. 2. 3. 4. 5. Advantages with Pottali kalpa : Long shelf life Compactness Easy to dispense Facility to carry in medical chest Does not spoil even in long journey

Pottali kalpana- definition, Etymology

Puta- Pota-Pottali-Pottalika Meaning: Puta means ±sanshlesha = to adhere=to give support, to keep intact Definition Pottali can be defined as to collect scattered material in to a compact dosage form to ensure long shelf life and usability.

CLASSIFICATION OF POTTALI

‡ ‡ ‡ ‡

According to Appearance According to Presence of Parada According to Gandhaka According to Agni with yantra

Steps in Pottali Preparation
‡ Steps: 1. Preparation of Pisti in the stipulated shape with agent 2. Wrapping with cloth 3. Cooking in Dola-yantra of Vidruta Gandhaka at regulated temperatures. 4. Removal of cloth and scraping of deposits.

‡ Ingredients‡ ‡ ‡ ‡ ‡ ‡ Ingredients of the formulation Binding agent Silk cloth Valuka yantra Thermometer Pottaliyantra

Pottali preparation clips of Tamragarbha Pottali

Tamra Bhasma Prweparation

Putapaka of Tamra bhama

Test of Bhasma- clips

Pottali Nirmana

Observations from Pottali kalpa
‡ Pottali paka should be done only on Mandagni in Vidruta Gandhaka as advocated by Acharyas. Gandhaka should attain Vyoma Varna as in this state Sulphur becomes solidified and will produce a good quality NON FRIABLE Pottali. ‡ Monitoring of Agni with a thermometer timely from 120oC to 220 C(Vyoma varna) is a must to attain correct paka.

Observations from Pottali kalpa
‡ During paka ingredients are saturated with gandhaka. ‡ This helps in increase in shelf life ‡ After consumption as it is less soluble and absorbs gradually after ingestion, increases the safety of the drug. (aborts upadrava) ‡ Though during preparation Rasa is used, no traces of Rasa(mercury) are found in finished product. This suggests that Rasa acts as only Yogavahi(catalyst) in the whole process.

Benefit of Pottali. ‡ The ultimate advantage of Pottali over conventional Bhasmas is in its ability to preserve the therapeutic efficacy of Bhasmas for a long time, with out compromising on the basic quality parameters of Bhasma viz., nischandra, rekhapurna and varitara.

Benefit of Pottali. Conclusion
‡ Contrary to popular belief that Bhasmas have eternal potency, in practice it is observed that they also tend to degrade, become toxic if not preserved properly. Hence the need of pottali kalpana.

‡ Pottali kalpana should be looked at as advanced rasashastra (pharmaceutical technique) to increase the shelf life, therapeutic effects and safety of Bhasmas.

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