Antibodies.

By Molly Bolder

INT. BLOOD VESSEL - DAY A fade from black reveals the microscopic world. A variety of cells are flowing through a blood vessel in the body. As groups of blood cells pass by a group of B cells slowly float along the bottom of the blood vessel. A lone bacteria cell enters the shot and passes through, brushing the group of B cells. One B cell with a matching antibody rises up and grabs it. As they flow together down the vein the B cell connects itself to the bacteria and begins engulfing it along with the antibody it is attached to. As it does so it slows to a stop and begins to break it down. Other cells pass by the B Cell as it begins to produce an MHC2 protein which holds up a piece of the bacteria that the B cell absorbed. The B cell is now a professional antigen presenting cell. The shot fades to black. INT. BLOOD VESSEL - DAY Opening from black, the B cell is passed by a group of helper T cells as they enter the vein. One of these helper T cells has receptors that match the bacteria presented exactly and reaches for it. The T cell binds to the protein and bacteria using its receptors thus activating the B Cell. The now activated B cell begins to proliferate two kinds of B cells. First are the memory B cells, multiplying copies of the original B cell, and the other is the plasma cell, the matured B cell. The plasma cell releases many of the same kind of antibody and when it is finished it will become weak and die. During this the helper T cells are also proliferating two kinds of cells. It emits small protein molecules called cytokines which then enter other cells in the immune system and make them produce the memory T cells. Here the camera zooms out to reveal the same process happening around the cells by others and gradually fades out.