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CLINICAL PRESENTATION

ACUTE POISONING
CLINICAL PRESENTATION
CHRONIC POISONING
TARGET ORGANS
INVESTIGATIONS
SPECIMENS
• Blood
• Urine
• Liver
• Kidney
• Stomach and contents
• Hair
• Nails
MANAGEMENT
• A, B, C
• Fluid replacement to replace GIT
losses
• In acute setting
– Gastric lavage if patient presents
rapidly or radiography shows
arsenic still in the stomach
– Whole bowel irrigation with
polyethylene glycol
– Chelation therapy
• Dimercaprol
– Haemodialysis
MANAGEMENT
• Chronic arsenic poisoning
– Causes irreversible damage
– Chelation
• Relives clinical manifestations
• Reduces arsenic stores