Voice over Script for Making an Antibody

Inside the human body, an invasion is taking place. Red blood cells rush through an artery, which are soon joined by a swarm of invaders, bacteria. One of these bacteria we follow as it accompanies the others and the blood cells on a journey through the artery. Their destination leads to a lymph node, a vast network of chambers. When they arrive at the lymph node the bacteria immediately seek out their prey, defenceless cells called B Lymphocytes which are sitting just below. The bacteria start to violently shove the B cells about, although many of these B cells are of no threat to these kinds of bacteria. Only a few of them however will be able to grab the bacteria, those that have the bacteria’s antigen matching receptors. It’s like the bacteria are swimming through a time bomb waiting to go off. As we follow our bacterium, he is joined by another and they begin to swim together. Suddenly a B cell launches out and grabs the mate of our bacterium. Our bacterium manages to escape, until he darts into the grasp of another B cell. He is now trapped and unable to get away, helpless and stuck to the receptor of the B cell. The receptor matches the antigen on the bacterium’s body perfectly, fitting like a key in a lock. The B cell now pulls him into its body and consumes him. He begins to dissolve leaving just the antigens. With the antigens, the B cell pushes them outward and displays them on her membrane wall. With the antigens exposed she sits and waits, calling for further help. From another part of the lymph node, different kinds of cells awaken from their resting place. These are T Lymphocytes and they react and come to the call of the B cells. Our B cell is greeted by one of the T cells. He approaches her and begins gently touching her, carefully wrapping his tentacles around her, as they begin their courtship. They both lock their receptors together, thus allowing the T cell to pass information on to the B cell, telling her to start dividing. After the T cell has finished he swims off. Now activated, the B cell begins to divide. Some of her offspring become more B cells, while others become Plasma cells. These plasma cells start shedding their receptors, which now become antibodies. These antibodies seek out the bacteria and stick to them, rendering them harmless. Other antibodies exit the lymph node in search of the bacteria throughout the body.

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