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CAM101 Complete Course Notes Reduced Size

CAM101 Complete Course Notes Reduced Size

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Published by: haydenfarquhar on Jun 11, 2011
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05/07/2013

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Drugs must cross certain membranes to get to their required site of action, and this means the drug has to be
absorbed.

How easily a drug is absorbed depends on:
• drug structure (e.g. water or lipid soluble? proteins versus steroids?)
• drug size (e.g. lithium has an atomic weight of ~7, compared to large protein drugs such as insulin or
the influenza vaccine)
o most drugs have a relative molecular mass between 100 and 1000
caffeine mw = 194
testosterone mw = 288
penicillin mw =373
insulin mw = 5700

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