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1) Pharmacist: A Health Care Provider, Concept of pharmaceutical health care, Growth of 03 2) Compounding & Dispensing of medication: Definition of dispensing & compounding.
Good dispensing & compounding practices, fundamental operations in compounding. Containers & closures for dispensed products, labeling & storage of compounded products. Dispensing of prefabricated dosage forms, patient counseling, and documentation of compounding & dispensing records. 3) Prescription: Its parts, types of prescription, prescription pricing & documentation. 4) Incompatibilities: Definition types o fprescription, prescription pricing & documentation 5) Pharmaceutical Calculations: - % Calculations, Allegation method, isotonicity, proof spirit. Posology: factors affecting & Calculations of doses. Weight & measures. Section – II TOPICS 6) Compounding & Dispensing Aspects of i) Formulation & procedure for compounding & dispensing of oral & external use liquids.,gargles, nasal drops, sprays, enemas. ii) Suspensions: - Thickening agents, Diffusible & in diffusible type, oral suspensions & lotions. iii) Emulsions: - Emulgents, choice of emulgents, HLB values, two phase emulsion, methods of preparation (Dry & wet gum & soap emulsions.), determination of type, physical stability & causes for instability.. iv) Semisolids: - Ointments, Creams, Pastes, jellies, Poultices & Plasters. v) Suppositories: - Formulation, displacement value, compounding & evaluation. vi) Solid Dosage Forms: - Divided & bulk (oral & external) powders, effervescent granules. Filling of Hard gelatin Capsules, dispensing of prefabricated Tablets, Capsules, Pastilles, Lozenges, Pills & tablet triturates. 7) Surgical Aids including Ligatures & Sutures: Surgical dressing, medicated bandages, Ligatures & Sutures processing and manufacturing, packing & Q.C. test of catgut Hrs. 04 04 04 07 02 07 03 07 05 10 04
TOTAL Hrs: - 45 Books Recommended: 1. AH. Gennaro Remington's Pharmaceutical Science-(Mack Publishing) 2. Collett & Aulton Pharmaceutical Practice 3. Hoover Dispensing of Medications (Mack Publishing) 4. Sprowls Prescription Pharmacy Lippincott) 5. Stocklos Pharmaceutical Calculations 6. IP, BP, USP-NF, NFI and the Pharmaceutical Codex, Martindale Extra Pharmacopoeia 8. Winfield and Richard Pharmaceutical Practice
P111- Dispensing Pharmacy (Practicals) (3 hrs/ week) Notes: (i) (ii) (iii) (iv) 1. 2. All the prescriptions shall be in metric system except a few for practice which shall be in the imperial system. Latest editions of books wherever applicable shall be used. Special attention to be paid to the cleanliness and precise working (including documentation) of the candidate in the laboratory. Minimum thirty exercises should be conducted Dispensing Vs Compounding Weighing technique for the dispensing-balance sensitivity - Weight box calibration and - accuracy. Precision of weighing and error evaluation. Measuring techniques - Precision and accuracy of measuring and error evaluation Devices for accurate dosage measurement Handling of prescription - Reading, checking, labeling and dispensing with detailing. General Dispensing procedure - Different containers for dispensing, labeling of dispensed medicines Documentation. 3. Posology and calculations Weights and measures Reducing and enlarging formulae Percentage calculations Dilutions and concentration (Stock solutions) H.L.B. System Isotonic solutions 4. Compounding and dispensing with precision of the following preparations: (I) Powders and Granules Compound Magnesium Trisilicate oral powder* Siedlitz powder* Isapgol granules** Effervescent granules of sodium sulphate** Zinc, starch and Talc Dusting powder* Eutectic powder containing Menthol with camphor* (ii) Solutions Salicylic acid colloid* Paediatric ferrous sulphate oral solution* Zinc Sulphate and Zinc chloride mouth wash* Mouth wash containing Thymol, Menthol, Peppermint oil and a suitable antiseptic.** (iii) Suspensions Paediatric kaolin mixture** Magnesium Trisilicate mixture** Paediatric chalk mixture** Inhalation containing menthol and eucalyptus* (iv) Emulsions Emulsion for internal use containing acacia White liniment* Oily calamine lotion** Benzyl Benzoate application*
Pharmaceutical Calculations Scheme for practical Examination Sr. 8. capsules (1)*.(v) Ointment Sulphur ointment** Whitfields ointment** Methyl salicylate ointment** Lubricating jelly** (vi) Suppositories Use of displacement value** Suppository with fatty base** Suppository with PEG base vii) 5. pastilles (2)*. 6..Dispensing of Medication Martindale -The Extra Pharmacopoeia Merck Index Remingtons Pharmaceutical Sciences Bradley -. tablet triturates (2)*. 3. Preparation of Lozenges (2)*. Pre-packaging and bulk compounding of any one dosage forms* Drug information .* ** Indicate Major experiments * Indicate minar experiments Books Recommended: 1. 4. 6. 5.An exercise on drug information. 10 Sprowls . Zatz -Pharmaceutical calculations Stocklos .Pharmaceutical calculations Joel L. 2. 1 2 3 4 5 Head Synopsis Major experiment Minor experiment Viva Journal & Attendance Total Duration Sessional 05 07 04 04 10 30 03 Hrs Annual 10 35 15 10 70 4 Hrs 3 .12th edition Collett & Aulton -Pharmaceutical Practice Hoover.Prescription Pharmacy Cooper & Gunn . 7.Dispensing for Pharmacy students . 9. pills (including Ayurvedic Pills) (3)*.No.Source .
iron .T112 PHARMACEUTICAL INORGANIC CHEMISTRY-I (4 Hrs/Week) SEMESTER. 4. 2. Electrolytes used for replacement therapy • Acid base balance. Minerals supplements. Pharmaceutical buffers. Bases.I Sr.(Dekker series) 5. Jeffery. More 7. Indian Pharmacopoeia 8.No. Inorganic Medicinal & Pharmaceutical Chemistry By Block & Roche. 6. Iron & Haematinics. heavy metals . Remington’s Pharmaceutical Sciences. Text book of Pharmaceutical Analysis By Dr. 3. By Chatten L. 4 . buffers in pharmaceutical systems. Text book of Pharmaceutical Chemistry. Preparation. British Pharmacopoeia 9. chloride and sulphate and Pharmacopoeial standards Section – II Limit tests: Chlorides and sulphates according ot pharmacopoeial standards Gastrointestinal Agents Acidifying agents. 1 Topics Section – I Acids.G. Textbook of Pharmaceutical analysis By Connors K.A.of hours Hours 10 2 08 3a 04 3b 4 04 12 5 07 45 Books Recommended: 1. Buffers Types & Mechanism. buffered isotonic solutions. Major Intra & Extra cellular Electrolytes • Physiological ions. H. By Beckett & Stenlake. • Combination therapy Limit tests: for arsenic . Vogel’s Textbooks of qualitative Inorganic Analysis By Denny. lead . Antacids. N. Practical Pharmaceutical inorganic chemistry. Buffer equation and buffer capacity in general. stability. Total no. measurement of tonicity and calculation and methods of adjusting isotonicity. protective Adsorbents Cathartics Essential & Trace elements Transition elements & their compounds of Pharmaceutical importance.
N. Scheme for practical Examination Sr. 2. By Beckett & Stenlake. British pharmacopoeia 9.A. Textbook of Pharmaceutical analysis By Connors K. 3. 1 2 3 4 6 Head Synopsis Major experiment Minor experiment Viva Journal & Attendance Total Duration Sessional 05 07 04 04 10 30 03 Hrs Annual 10 35 15 10 70 4 Hrs ** Indicate Major experiments 5 . Jeffery. Text book of Pharmaceutical Analysis By Dr. Indian Pharmacopoeia 8.No. Practical Pharmaceutical inorganic chemistry. Vogel’s Textbooks of qualitative Inorganic Analysis By Denny. 4. Topic 1 Systematic qualitative analysis of inorganic mixtures containing two anions and two cations. By Chatten L.(Dekkerseries) 5. 6.P112 PHARMACEUTICAL INORGANIC CHEMISTRY-I Duration: 3Hrs/week Sr. Inorganic Medicinal & Pharmaceutical Chemistry By Block & Roche.G. (Minimum five practical) ** 2 Limit test for following as per the procedure given in Indian pharmacopoeia (1996-including the latest addendum )* chloride Sulphate Heavy metals Iron Arsenic 3 Preparation of inorganic compounds* (Minimum five practical) * Indicate minar experiments Books Recommended: 1.More 7.No. Remington’s Pharmaceutical Sciences.H. Text book of Pharmaceutical Chemistry.
cyanocobalamine. Ca++ ATPasae. hormones) Lipid Metabolism: B. cytoskeleton. flow of informationreplication. study of lipoproteins. kidney. Aplication of protein structure database in drug design. Rancidity. 06 Proteins and amino acids: Functions of proteins and their classification physicochemical properties of proteins.Folic acid. study of amino acid. and their role in lipid metabolism. gluconeogenesis. biological value of lipids. changes in lipoproteins profile in various disease conditation. ion-exchange chromatography.Biosynthesis of unsaturated fatty acids. ribosome.Lipases. Different types of lipopriteins . membrane bound Adenyl cyclase. –chemical coupling • conformational coupling • Chemoiosmotic coupling • hypothrsis. Lac operon.oxidation. centrifugation and affinity chromatography (Explain elementary idea and outline the method of separation) Protein structure at various level primary. study of insulin receptor Section II Boienergetics: energy flow in biological system. Watson and Crick model for DNA structure. Activators and inhibitors of enzymes. Cardiolipin. Lipids: Defination. glucogenic amino acids. oxidative deamination. Cholesterol biosynthesis. mutienzymecomplex. experimental evidences indicating DNA as a genetic material. Biological oxidation: ETC. mechanism of oxidative phosphorylation viz.Prostaglandins their biochemical role and biosynthesis. and ATP synthetase • complex. Phospholipids . (Drugs acting at various levels) Mutation and DNA repair .Formation of keton bodies. endoplasmic reticulum. structure. glycogenesis.ketogenic amino acids.T113 Biochemistry: Theory (4 hr/week) Sr. Isoelectric point. glycogenolysis. Niacin. transportation.competitive. Cholesterol. membrane receptors. Fat soluble vitamins A. Pharmaceutical application of enzymes. Sphingolipids. analysis of fat. Different methods for separation and purification of proteins and amino acids. Nerve. and significance of phospholipids essencial and non essencial fatty acids. translation.High energy • compounds. E . Protein metabolism: • Integration of protein metabolism with glycolysis transamination.non oxidative deaminatin. oxidation of fatty acids. insulin. pyridoxine. D. ATP cycle.K. peptides. acid base property. oxidative phosphorylation. Golgi apparatus.ATP synthesis. mechanism of enzyme action factors affecting rate of enzymatic reaction. secondary.Iodine value. Enzymes: Classification. riboflavin. Genetics: Structure of DNA and its role as a genetic material. 02 Hours 2 02 3 04 4 06 5 06 6 08 7 08 8 9 02 02 10 08 11 08 12 04 6 . structure of insulin. TCA cycle. Bio-membranes: Structure of membrane. protein kinase and phosphodiesterase. teriary and quaternary.No. Antioxidants Carbohydrate metabolism: Glycolysis (aerobic and anaerobic) . and diffusion. and classification . physiochemical properties of DNA . Control of gene expression . Na+ k + pump. catabolism of individual amino acids. nucleus. pentose phosphate pathway.vitamin C . Enzyme induction and Isozymes.Pantothenic acid . mitochondria plasma membrane. • Synthesis of physiologically important substances from amino acids (neurotransmitters. classification. saponification value.types of lipoproteins. Competitive and non. Inhibitors of oxidative phosphorylation including • uncoupling in brown adipose tissue. changes in LP profile in various disease condition. urea cycle . Vitamins and coenzymes : Structure and functions and biochemical role of coenzyme from water soluble vitamins folic acid thiamin. Biochemistry of specialized tissue. reverse transcription. Essential and nonessential amino acids. 1 TOPIC Section-I Animal cell Structure and function of different organells. liver and muscle. mechanism of action of insulin. biosynthesis of fatty acids. allosteric types of nzymes inhibition with respect to drug action. membrane potential. biosynthesis of insulin. lysozome. acid value.
Szabo 4. Tex book of Clinical Chemistry – Alex Kaplan & Laverve L. * Separation of amino acid by paper chromatography.No. ** A. precipitation reaction. * Identification of unknown substance of biomedical importance. Quantitative estimation of carbohydrate by follin Wu method ** Quantitative estimation of glucose in urine by Benedict method ** Standardization of glass ware.(Demonstration) * Isolation of DNA * ** Indicate major experiments 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 * Indicate minor experiments Books Recommended: 1. study of biological variation. morality. * Titration to find out acidity of gastric juice by titrating it against potassium hydroxide or sodium hydroxide.(Demonstration) * Separation of lipids by thin layer chromatography. * A study of activity of enzyme salivary amylase. Harpers review of biochemistry – Martin 2. Text book of biochemistry – Ramarao 6. molality. 1 2 3 4 6 Head Synopsis Major experiment Minor experiment Viva Journal & Attendance Total Duration Sessional 05 07 04 04 10 30 03 Hrs Annual 10 35 15 10 70 4 Hrs 7 .No. ** Qualitative tests for proteins. percent solution v/v and w/v. paper electrophoresis of serum protein. gms/litre etc. Text book of biochemistry – D. * Expression of concentration such as normality. (demonstration) * Care and use of pH meter constrict titration curve for amino acid alanine. * Determination of ascorbic acid using dye 2. * Preparation of normal (N) solution. B . sources of errors. 1 2 TOPIC Qualitative tests for carbohydrates. 6 dichlorophenol indophenol. Practical Biochemistry – Pattabhiraman Scheme for practical Examination Sr. * Determination of acid value of given fat sample. Practical Biochemistry – David T. Principles of biochemistry – Lehninger 5. Satyanarayan 3.Total no of lectures 60 P113 Biochemistry (Practical) Sr. * Identification of given fat sample. percent. * Electrophoresis. Plummer 7.color reactions.
Principles of anatomy & physiology.. 1993. Human Physiology. 4) Chatterjee C.Mono-Poly-Plantar h) Cranial Nerves.structure. Sherman. Enders. New Cenrtal Book Agency. No. 2) Vander. 5) Ross and Wilson. 1984. “ Bailey`s TextBook of Microscopic Anatomy”. New York 1996 8th edition. Types of movements of joints and c)disorders of joints (definitions only) (a) :To be done in practical classes-6 hrs Haemopoietic System a) Composition and functions of blood and Blood components b) Haemopoiesis c) Blood groups d) Haemostasis-Clotting factors and mechanism Lymph a) Lymph and lymphatic system composition. Mc-Graw Hill Publication New Delhi 1998 7th edition. Harper Collins College Publishers. Anatomy and Physiology in health and illness. 6) AB Mc Naught and Callander R. CSF –formation and functions Blood Brain Barrier. 2nd edition 8) Douglas E. B.Names and functions. 3) Tortora G. Luciano. maintenance and regulation No of Hrs 1 2 3 4 5 01 02 02 02 01 6 02 01 01 02 02 01 01 01 01 01 02 7 8 9 02 01 02 01 01 02 01 02 02 01 02 10 01 02 01 01 01 01 Books Recommended: 1) Guyton & Hall.Sr. Churchill Living Stone. Medical allied agency. “Consise Medical Physiology”. 18th Edition 8 . 9th edition.reflexes. New Delhi. Williams and Wilkins publishers.. Formation. muscular and nervous tissuestheir sub-types and characteristics Homeostasis Various mechanisms to maintain homeostasis a)Osseous system . Histology and Physiology. 1st edition. Kolkata 2003 11th Edition. T114 Human Anatomy & Physiology (3hrs/Week) Chapter The topics which were covered up to 10 + 2 should be covered with more details as given in books recommended to increase the depth.J. basic terminologies used in this subject (Description of the body using planes and terminologies) Structure of cell-Its components and their functions (details). Section-I Scope of Anatomy and Physiology. Elsevier. Neuronal Circuits. “ Illustrated Physiology”. Churchill Livingstone 2001. Kelly. coronary & systemic circulation c) Conduction and ECG d) Cardiac cycle and Heart Sounds f) Blood Pressure . Richard Wood and Allen C. Cardio vascular system a) Anatomy of heart a) Blood vessels and circulation b) Pulmonary. Process of cell division and protein synthesis Elementary tissues of the human body :epithelial.C. 2000 10th edition. and circulation b) Spleen : Physiology and Function Endocrine System ( introduction) a) Pituitary gland b) Adrenal gland c) Thyroid and parathyroid glands d) Pancreas and gonads Section-II Nervous System Neuron. a) Definition and classification of nervous system b) Functional areas and functions of cerebrum c) Cerebellum d) Pons and medulla e) Thalamus and Hypothalamus f) Basal ganglion g) Spinal cord: Structure and functions. ANS-Anatomy and functions of sympathetic and parasympathetic N. Human Physiology. 987. London.. Textbook of medical physiology.I. 7) Chaudhry Sujit K.S. Calcutta. composition and functions of the skeleton b)Classification of joints. connective. New Delhi.
Jaypee Brothers. “Human Anatomy and Physiology”. 10) Inderbir Singh. 2002. New York. New Delhi. “ Text Book of Human Histology with Colour Atlas. 9 . 1997 4th edition.09) Elaine N. Addison Wesley. Marieb. 4th edition.
B.II. Determination of R. Determination of blood pressure** 9. Text Book of Practical Physiology. content of blood* 4. New Delhi. Bharihoke V. Pradhan S.A.B.NO 1 2 3 4 5 6 Head Spotting / identification Synopsis Major experiment Minor experiment Viva Journal & Attendance Total Duration Annual 10 10 30 15 10 70 4 Hrs 10 .S Publication. Joshi P. Determination of blood groups** 8. Mukherjee K. content of blood* 5. Pune Vidyapith Griha Prakashan. Determination of differential count of blood* 6. Study of Microscope# 2. Pune.C. Medical Laboratory Technology.1999 4th edition (Vol. Determination of bleeding time and clotting time** 10. Text book of Histology .B.T. 1997 2. Ranade V.L..I. Determination of W. Tata McGraw Hill. 2005.I.N. Study of histology using permanent slides # 12. Determination of ESR* 3.P114 Human Anatomy & Physiology (Practical) 1.G.C. Study of various systems using Charts/ Models# 11. Determination of hemoglobin content of blood ** 7.III) 3. 2nd edition Scheme for practical Examination Sessional 04 04 07 03 02 10 30 03 Hrs SR. Study of skeletal system# #-Experiments for preliminary knowledge and may be examined in form of identification/spotting * Indicate Minor Experiment ** Indicate Major Experiment Books Recommended Books1.
11) Pharmacist and community pharmacy 12) Community health care concepts. functions of the committee. Charting of pharmacy organization. (PPI). personal in organized health care setting . central storage vs. design and layouts. control of narcotics by nurses . pharmacy education. Hospital contractual relations. 13) Health program in India:. 9) Techniques in radio pharmacy and clinical applications of radiopharmaceuticals: Introduction to particulate radiation. modification in registration . Blood bank. storeroom arrangement . Drug experience reporting. medical staff. pathology service. facilities required. support service. registration Exemption for hospital house staff. brand named drugs. labeling and packaging requirements. Health policy. qualities for successful counseling. health promotion. other systems.offenses and penalties. Shah Prakashan) Hassan . ofessional service s Rendered. separate registration for independent activities. managing computers systems development ASHP technical assistant bulletin on hospital Drug Distrubition and control. clinical departments.AIDS. public health. preparation of radiopharmaceuticals kits. barriers and outcome of patient counseling. model sets of hospital controlled sustenance’s regulations. protocol for reporting drug abuse or diversion . taking of physical inventory . perceptions . 5) Hospital Formulary: Format and appearance of the formulary.T115 Hospital and Community Pharmacy Duration: 3Hrs/week Section -I TOPICS 1) Hospitals. role of purchasing agent in drug procurement . control on purchases. specials uses. the perpetual inventory . women in pharmacy. sample pharmacologic index . formulary drug listing service formulary drug listing service preparation . nursing service. program criteria. 8) Dispensing of Controlled Substances: Comprehensive Drug abuse prevention and control Act of 1970. Health maintenance Organization. levels and systems. Generic vs. purchasing procedure . Section II 7) Purchasing procedure and Inventory control: Procurement: Drug selection . Determining the departmental staffsprofessional . drug information specialists. responsibility and control .Classification. Total no. publication . model computer regulations. therapeutic and diagnostic radiopharmaceuticals. committees role in developing emergency drug list. Times for application for registration . Hospital Pharmacy (Lea and Febiger) Hrs. medical social service departments.National health programs. methods.S. expiration of registration . barriers and outcome of patient counseling. inventory requirements. protection of operators. medical records department. Miscellaneous regulations . preparation of the formulary. 04 01 02 05 05 05 03 04 02 02 01 03 03 04 22 45 11 . marking of merchandise. categorizing and indexing . Evaluation of drugs.(B. Drug catalogue or list. bound . anesthesia service. exemption of agent and employees. membership. job Descriptions. role of pharmacist in drug procurement. conteins . quality of drug . committees role in the adverse drug reaction program. loose –leaf vs.Objectives. schedules for controlled substances. radiology. shelf stripping and floor. Registration Requirements .marking . Hiring of pharmacists . authority of control . health team. selection of guiding for admission or deletion of drug . Central service department. material management. narcotics delivery to nursing station . control of personnel . keeping the formulary current. the committee agenda. advisory labels. 14) Practice of patient education and counseling:. 10) Use of Computers in Hospital: Terminology. prescription writing . application forms . Organization administration governing body and management. Recommended reference materials. separate registrations for separate location . Tuberculosis and child health. distribution of the formulary. of lectures otal Hrs: Books Recommended: Merchant & Qadry . education and rehabilation. 2) Hospital Pharmacy: History and Development 3) Duties and Responsibilities of Hospital Pharmacist 4) Pharmacy and Therapeutic Committee: Purpose of committee. Salaries. recommendations. purchasing authority. control of dated or perishable inventory . use of non-formulary drugs. Impact of the computer on dispensing time. half life. functions. departmental staffs-lay personal. specialty formularies. medical compliance and patient information leafletscontent. committee name. dietetic service. frequency of meeting. text. contract management.the legal basis of the formulary system. Discounts . Anti substitution laws and the formulary. Automatic stop order for dangerous drugs.format. Text book of Hospital Pharmacy . formulary vs. size . pharmacy storage . 6) Organization and Personnel: Pharmacy specialist .
Pharmaceutical Practice 12 . Health education and Community Pharmacy WHO consultative group report Robin J Harman. Hand book of Pharmacy (The Pharmaceutical Press) Winfield.Parmar N S. Richards-.
methods of determining size distribution 12) Powder mixing: Mechanism of mixing. tanks baffles. 8) Solutions: Factors affecting rate of solution. Formulation development based on different aspects including physicochemical studies. biopharmaceutical and technical aspect. ball mill. Formulation. Leon Shargel. factors influencing size reduction grinding mills of various types like hammer mill. dosage forms and their classification :a) Reasons to develop dosage forms.) Hrs. 3) Definition of drug and development of new drug 4) Pharmaceutical Excipients: Organoleptic additives. Wells. plate and frame filter. Dittert . paddle mixers. Manufacturing process and equipments.B. Groves. talcum powder. multimill.Modern pharmaceutics-(Dekker) 7. oral dehydration powder.(J. Ansel. aromatic waters. patient acceptance 7) Powders and granules: Formulation.) 8.Hand Book of Package Engg.Popovich & Allen-(Willams and Wilkins) Pharmaceutical dosage and drug delivery systems3.(McGraw Hill) 9. various types of trough mixers. fluid energy mill. Introduction to pharmacopoeias (IP. David Gaderton. Bentleys Text Book of Pharmaceutics. Rawlins .5th edition 11. Packaging (Glass and plastic containers). 13. pravantion of aeration and foam Total Hours: Books Recommended: 1. filter media. preparation and evaluation of various powders and granules.I TOPICS 1) Introduction to pharmaceutics and its scope: 2) History of pharmacy: Historical background and development of profession of pharmacy and pharmaceutical industry in India. Planetary mixer 13) Unit processes and equipment used for manufacturing of non sterile monophasic liquids. Extra Pharmacopoeia and European Pharmacopoeia. 5) Introduction to Pharmaceutical Equipments used for solid dosage forms 6) Introduction to Routes of Administration. linctuses. Tutorial Pharmacy.Remington: The science and practice of pharmacy. sigma and ribbon blenders. Quality control standards (Viscosity determination. sparkle. propeller type mexers. impellers. dry syrup formulation.USP. filter aid : Nutsch filter. sifting.) 5. belt conveyer cartooning and batch numbering. Preservatives. elixirs. Lipincott) 4. leaf filter. size gradation.T121-Pharmaceutics-I (Theory) (3Hrs/week) Section. conico cylindrical. Equipment used in the production of powders and granules. American pharmacy. mechanism of liquid mixing.Parental products-(William Heinemann Medical Books Ltd. mouthwashes. Section-II 9) Filtration and clarification: Factors affecting rate of filtration.(Mack publishing Co. tumblers like cube and double cone. BP. therapeutic. Banker and Rhodes. Gennaro . Equipment used for manufacturing and packaging of liquids: bottle washing and machine filling equipment. ENT Preparations and paints. edge and end runner mill. Cooper and Gunn. 11) Size separation : Sieves. rotary vacuums filter. tooth powder. 01 03 01 03 03 04 03 05 07 04 04 04 03 45 13 .BPC and NF of India . Swarbrick and Boylon: Encyclopedia of pharmaceutical technology (Dekker) Vol 1-3. Antioxidants. weight per ml and specific gravity. Formulation aspects of syrups. hydroextractors (basket centrifuge) 10) Size reduction: Importance in pharmacy. Lachmann.Libermann & Kanig. James J. Hanlon. size distribution.Pharmaceutical preformulation (Ellis Horwood Ltd. Products like dusting powder.Pharmacy review (John Wiley and sons) 12.Unit processes in pharmacy(William Heinemann) 10.(ELBS) 6.Industrial pharmacy (Lea & Febiger) 2. preformulation and formulation development: Physicochemical properties of drugs substances. Alfonso R.
4.P. Cough syrup 4.C* 4. Surgical chlorinated soda solution B. Tooth power * Indicate minar experiments Books Recommended: 1. Flavoured syrup E) Elixir: ** 1.P.C F) Linctus: * 1.C* 6. 5.P. 2. Magnesium citrate solution N.P. Ansel. 9. Dill water B. Nasal drop Paint** 1.P*.P. 3. Pharmaceutical Practice Scheme for practical Examination Sr.No.F. Chloramphenicol ear drop OR Gentamycin ear drop 2.C G) Ear and nose preparation** 1. Mandles paint B. Anise water B. Artificial syrup 3. Vallabh Prakashan Delhi) M. Piperazine citrate elixir B. (Mack) Harkishan Singh.P. Conc. Richards. Paracetamol pediatrics solubilized drops** B) Aromatic waters: 1.) * 2..P.S.C. 2.Lipincott) Martin. 1 2 3 4 6 Head Synopsis Major experiment Minor experiment Viva Journal & Attendance Total Duration Sessional 05 07 04 04 10 30 03 Hrs Annual 10 35 15 10 70 4 Hrs ** Indicate Major experiments 14 . Conc. * 3.P. Gripe water** C) Glycerites: * 1. Effervescent granules** 3.P.P. U. Industrial Pharmacy (Lea & Febiger) I. 10. B. Aqueous iodine solution (Lugol I. Aulton..P. Pharmaceutics Winfield.L. D) Syrups: * 1. B. Dill water* 3. Tincture of iodine I. Dry syrup* 2. Glycerine of Boric acid I. * 5. Pharmacopeias and Formularies.P.P. Introduction to pharmaceutical dosage forms (Lea and Febiger) Dittert.P. Shroff General Pharmacy Series Mittal. Glycerine of starch I. 2. Chloroform water* 5. 6.C H) Powders: 1. Oral rehydration powder * 4.P..* * 4. Cresol with soap I.P. 8. 7. Sprouls American Pharmacy (J. Remington's Pharmaceutical Sciences. Talcum powder * 5.B. Pharmaceutical Formulations Lachman. Simple syrups I. Tannic acid Glycerine I. 2.P121-Pharmaceutics-I (Practicals) (3hrs/week) A) Solutions: 1. Simple linctus B. 3.
fuller’s earth. Isapghula. Topic General Pharmacognosy: Definition. morphological. History and Scope of Pharmacognosy Indian & International trade in Medicinal & Aromatic plants. Drugs of Natural Origin Sources of drugs:Vegetable. animal. marine. b. Shilajit. coral . d. Talc. 3 8 Adulteration: Definition. pharmacological. & preparation aspects Turmeric. Quality Control of crude drugs: WHO guidelines for quality control of crude drugs. Detailed study of methods of cultivation. Calamine . 6 6 3 4 7 Study of Mineral Drugs (Source. processing and storage of crude drugs. Systems of Classification of crude drugs. Exogenous and endogenous factors affecting cultivation . mineral & plant tissue Scheme for Pharmacognostic study of crude drugs. Uses. & Instrumental 15 . & Pharmacology): Bentonite. taxonomical and geographical 3. collection. & cell inclusions. Types. 7 Section II 5 Detailed study of Cultivation. f. Kaolin. a. Chemistry. cell wall. Study of plant cell and tissue structure. Merits and demerits of cultivation. Alphabetical. e. sterilization & preparation for market) Study of following drugs with respect to cultivation. chemical. determination of adulterants by Organoleptic. g.T122 Pharmacognosy-I Theory (3 Hrs / Weekly) Section I Sr. Chemical. 3 4. c. B) General morphological & microscopical characteristics of plant parts with examples. 1. Leaves Barks Woods Stems Flowers Fruits Seeds Substerian drugs 8 6 Hrs. quality of crude drugs & Collection and processing (Garbling. preservation & storage. collection. tissues. 2. h. drying. A) Study of cells. Microscopic.No. Physical.
E. Iyengar M. Chopra R. 6.B.. Raw Marerials (All Volumes). . P. Brady. ash value*. Advances in Horticulture Vol II. Cultivation and utilization of Medicinal plants.. and Kapur B.A. K.E. C.. compound microscope. C. 9. U. ** 7.L. Whistler R. Iyengar M.. Manipal.medicinal and aromatic plants. Fahn A. Pharmacognosy. Determination of palisade cell ratio of leaf drugs. microtome and digital photographic microscope. Academic Press London. and Chopra I. Pharmacognosy 20. Study of simple microscope. Practical Pharmacognosy. Vallabh Prakashan.E. 12th Edition. Pergamon press. K.. W.Academic Press. Medicinal Plants of India. extractive value*. R.A. New Delhi. G. 3. Manipal Power Press. 3rd Ed. Manipal Power Press. Morphological and histological study of different parts of plant mentioned under: Chapter three**(Minimum 4 practicals) 3. Council of Scientific and Industrial Research. (Minimum 2 practical) * Indicate minar experiments ** Indicate Major experiments Books Recommended: 1. Practical Pharmacognosy. D. Quantitative microscopy: **(Minimum 4 practicals) 4. The Wealth of India. The practical Evaluation of phytopharmaceuticals 5. 4. Purohit A. Swain T. Industrial Gums.K. Chemical Plant Taxonomy. 13. Analytical Microscopy.A..E. V.P122 Pharmacognosy-I Practical (3 Hrs / Week) 1.. M. 11. 16. Churchill Limited. Khandelwal KR. Churchill Limited. Brain K..No. Bailliere Tindall. Textbook of Pharmacognosy. Camera Lucida. Pharmacognosy Lab Manual. Academic Press London. Wagner. Wallis. Polysaccharides and their derivatives. 14. 7. RRL. Delhi. 8. 22. 2. Plant drug Analysis.. and Gupta R. Measurement of starch grains*. 10. 15. and Evans. Tyler.D. V.Rangari. Jammu. Determination of stomatal number and stomatal index of leaf drugs. Plant anatomy. 2nd Edition. 12.C. L.C. Determination of vein islet and veinlet termination number of leaf drugs. Zgainsky. A Class Book of Botany. ** 6.Dutta. Trease. 19. 21. Atal C. foreign organic matter and swelling index of crude drugs. Eastbourne. New Delhi. J. Glossary of Indian Medicinal plants CSIR. and Gokhale S.. calcium oxalate crystals *and phloem fibers* in powdered crude drugs. London. 17. Publisher. Nayar S. Pharmacognosy and Phytochemistry. . A. Wallis. Kokate C. N. S. Comparative Phytochemistry. 18. Study of Crude Drugs. T. T. Determination of moisture content*.. B. J.A.S. Zafar R. Kokate C. Pharmacognosy (degree ) Nirali Prakashan 2. and Turner T. K.L. 1 2 3 4 5 6 Head Spotting / identification Synopsis Major experiment Minor experiment Viva Journal & Attendance Total Marks Duration Sessional 04 04 07 03 02 10 30 03 Hrs Annual 10 10 30 10 10 70 4 Hrs 16 . Chandha K. R. ** 8.B. Manipal. Volume I & II Scheme of practial examination Sr. Swain T. Oxford. Nirali Prakashan Pune. London. 5.
choice of indicators. Isoniazide. types of errors. • Metallochrome indicators (no structures). neutralization curves. mixed indicator. indicators. cerium (IV) sulfate.Sr. T123 PHARMACEUTICAL ANALYSIS –I Duration: 3hrs/week SECTION I Topic 4 07 5 20 05 6 04 7 03 8 Gravimetric analysis: 06 • Precipitation techniques. titration methods• Mohr’s. Non-Aqueous titrations: 03 • Types of solvents. Oxidation-Reduction titrations: • Theory of redox titration. • Applications in assay of Benzoic acid. Miscellaneous methods of analysis: • Diazotization titrations. • Applications in assay of Potassium chloride. Iodine (Iodimetry and Iodometry). potassium iodate. Gay lussac. Hydrogen peroxide. measurement of electrode potential. end point detection. redox Indicators. Lead nitrate and calcium gluconate. Ascorbic acid. Sodium benzoate. post precipitation. ignition. supersaturation. and Fajan’s method. Fundamentals of volumetric analysis. • Selection of sample. factors affecting solubility of a precipitate. solubility products. of lectures Complexometric titrations: • Theory. • Titrations involving potassium permanganate. Total no. hydrolysis of salts. • Application in assay of Magnesium sulfate. colloidal state. • Application in assay of Sodium acetate. titanous chloride. of lectures 18 17 . Argentometric titrations: • Theory. types of EDTA titrations. Norfloxacin tablet. titration curves. different techniques of analysis. formation of complex and its stability. Aspirin. filtration. Aqueous Acid-Base titrations: 05 • Law of mass action. Applications in assay of Ferrous sulfate. • Theory of indicators. potassium bromate. potassium dichromate. precision and accuracy. primary and secondary standards. • Calculation of equivalent weight and Stochiometry. Calcium as calcium oxalate and magnesium as magnesium pyrophosphate. Sodium chloride and Ammonium chloride. weighing and calculation. • Application in assay of Alum by oximereagent. Total no. methods of expressing concentrations. Volhard’s. 04 preliminaries and definitions.No. • Oxidation-reduction curves. 1 2 3 Hours Introduction: • Significance of quantitative analysis in quality control. Boric acid. • Kjeldahl’s method of nitrogen determination • And Oxygen flask combustion method. digestion. coprecipitation.
3. Analytical chemistry.Garrat 4. 8.A. Ceric ammonium sulphate . Boric acid.* Assays of oxalic acis/ hydrogen peroxide. sodium thiosulfate etc. the precautions to be taken during handaling of analytical balance. European Pharmacopoeia.B.K. potassium dichromate . Vogel textbook of quantitative chemical analysis 8. Ammonium chloride. The students should also be acquainted with use of appropriate apparatus for various analytical procedures. International pharmacopoeia 2. H2SO4) Bases ( NaOH) .** Non –aqueous Titrations: Preparation and standardization of perchloric acid and sodium/ potassium/ lithium methoxide solutions* Assays of amines or amine hydrochlorides. 7. 10. Calibration of analytical weights and of volumetric apparatus like volumetric falsk . 5 6.* Assay of Sodium chloride. pipette. USP.No. ** Complexometric Titrations: Preparation and standardization of EDTA solution. potassium chloride.Beckett and Stenlake Scheme for practical Examination Sr.P123 Pharmaceutical Analysis –I (Practical) Duration: 3hrs /week Sr. The quantitative analysis of drugs. sodium acetate.MEITES H.* Assay of magnesium sulfate. burette etc. Ferrous ammonium gluconate. Practical InstructionThe students should have a clear understanding of the principal and working of a typical analytical balance. 2.Skoog 7. Aspirin. ** Oxidation – reduction Titrations: Preparation and standardization of redox titrants such as potassium permanganate. ammonium thiocyanate. Guide for safety in chemical laboratory. Ascorbic acid/ Analgin ** Precipitation Titration: Preparation and standardization of tityrants like Silver nitrate. Connors 9. Assays involving Direct and Back titrations. Hardness of water** Gravimetric Analysis: Determination of Alum by oxime reagent. Sulphate as abrium sulphate/ Ni as Ni DMG complex. (Demonstration) ** Indicate Major experiments 1.Van Nostrand Reinhold co. norfloxacin tablet. Pharmaceutical analysis-Higuchi and brochmann 3. methods of weighing and erroe of weighing. lead nitrate. Benzoic acid.garry Chrisian 6. 1 2 3 4 5 Head Synopsis Major experiment Minor experiment Viva Journal & Attendance Total Duration Sessional 05 07 04 04 10 30 03 Hrs Annual 10 35 15 10 70 4 Hrs 18 . 4. Principles of instrumental analysis. calcium gluconate. Textbook of Pharmaceutical analysis. 5. Practical Pharmaceutical Chemistry Part-I . *Indicate Minor experiments Books Recommended: 1.BP.* Acid Base Titrations: Preparation and standardization of acids (HCl.No. ** Miscellaneous methods : Nitrogen determination by Kjeldahl method Sodium nitrite titration. Analytical chemistry. IP. iodine .
19 .L. non-bonded electrons). I and II ELBS / Longman. D & L). New Delhi 6. Oxazine e) Benzo-fused Heterocyclics. Polynuclear Aromatic Hydrocarbons: Naphthalene. No. Structure and Nomenclature (general and IUPAC) of Organic Compounds of the Following Classes: Hydrocarbons (Aliphatic. Saw-Horse. Boyd. chiral centres. Molecular weight. Nomenclature in stereoisomerism(configurations: R & S. Fats & Lipids. Inc. physical constants. 4.C. Sequence Rules Total on. d) Two Hetero atoms Six membered: Pyrazine. Van der Waals forces. Proteins. covalent. Biomolecules I: Carbohydrates. Morrison and R.Indole. Benzodiazepine. Of Lectures Allotted number of Lectures 3 2a 12 2b 06 3 08 4 16 45 Books Recommended 1. Conjugated dienes. types of bonding(ionic. Pregnanes and Sterols) SECTION II Correlation of physical properties like physical states. Cram and Hammond.Sr. Quinoline. Principles of organics synthesis by R. Bond strengths. Thiazole. Amino acids. c) Two Hetero atoms Five membered: Imidazole. saturated and unsaturated. 7. Alcohols. Stereochemistry of carbon compounds by E. elements of symmetry. Finar vol.L. Specific rotation. Enantiomers. solubility etc. Ltd. Eliel Mc. Aromatic). Meso-compounds. Ethers and Epoxides. Pyrimidine. Organic chemistry by Hendrickson. Amines. Conformational isomerism.R. with respective structures of above mentioned classes compounds Introduction to Stereochemistry: Isomerism. Organic chemistry by T. Heterocyclics: a) One Hetero atom Five membered: Pyrrole. Benzopyran. Fischer’s and Newmann’s projections of molecules.O. New York. Empirical formula Introduction. Hydrogen bonding. Dipole moment and polarity Fundamentals as Molecular formula. Stereoisomerism. Benzimidazole. Geometric isomerism. Reaction mechanisms in organic chemistry by Mukherjee and Singh. Norman 9. Diastereomers. Classification. Oxazole. 1 T124 Pharmaceutical Organic Chemistry–I (Theory) 4 h/week SECTION I Name of the Chapter Introduction to Organic Chemistry: Importance and properties of carbon. Phenols. Organic Chemistry by I. Frontier orbitals and organic chemistry by lan Flaming. Benzoxazole. Organic synthesis by Gilman and Blatt Collective vol 3 3. Prentice Hall of India Pvt. Introduction to organic chemistry – By Streitweiser and Health Cook 10. Graw Hill Book Co. Advanced organic chemistry by Bahl and Bahl 5. 8. Androstanes. Alkyl and Aryl halides. Carbazole. Carboxylic acids and their functional derivatives. chirality. Z & E. Racemic modifications. co-ordinate. Indanone. Furan and Thiophene. Bond length. Isoxazole. London 2. Phenanthrene and Dibenzocycloheptene. b) One Hetero atom Six memberd: Pyridine. Isothiazole. Anthracene. Aldehydes and Ketones. Optical activity. Isoquinoline. Pyran. Hybridization of elements Concepts of structural theory. Steroids (Estrones.
Lampman and G. London. Pavia G.* 3) Determination of physical constants of few organic compounds (both solid and liquid) and calibration of thermometer.** 4) Study of physical properties of organic compounds in correlation with their structures. Introduction to organic laboratory techniques – D. commonly used in chemistry laboratories. Practical organic chemistry – Mann and Sounders. Aliphatic & aromatic amines. 3.Vogel. 2.* 2) Preparation. ELBS and Longman Group Ltd.L. transfer & storage of chromic acid mixture.P124 Pharmaceutical Organic Chemistry – I (Practical) 3 h/Week 1) Introduction to the laboratory chemicals and apparatus.I. ELBS and Longman Group Ltd. 1 2 3 Type of questions Synopsis Viva-voce Experiment : Major Minor : Journal marks Total marks Sessional 5 5 10 10 30 University examination 10 10 30 20 -----70 4 20 . London. Examination Scheme: Sr. Aliphatic & aromatic aldehydes & ketones Aliphatic & aromatic amides.D.No. kriz. Phenols Aromatic hydrocarbons Carbohydrates 2) Introduction to the use of stereomodels with following examples** • Lactic acid • Tartaric acid • cis – alkene • Ephedrine • Trans alkene • Mesotartaric acid • Inversion of configuration *Indicate Minor experiments ** Indicate Major experiments NOTE: Minimum 14 experiments should be covered I) Books Recommended 1. Elementary practical organic chemistry – A. Compounds containing following functional classes to be considered** Aliphatic & aromatic carboxylic acid.
Total no. By Chatten L. Inorganic Medicinal & Pharmaceutical Chemistry By Block & Roche. of lectures 08 04 04 07 04 08 10 45 Books Recommended: 1. N. British Pharmacopoeia 9. Jeffery. Textbook of Pharmaceutical analysis By Connors K. Radiopaque contrast media Miscellaneous : Environmental Sciences • Water. Vogel’s Textbooks of qualitative Inorganic Analysis By Denny. 3. Indian Pharmacopoeia 8. Radiopharmaceutical preparation.(Dekker series) 5.G. H. Practical Pharmaceutical inorganic chemistry. Types Use of water in Pharmaceuticals as solvents. More 7. Remington’s Pharmaceutical Sciences. 6. Text book of Pharmaceutical Chemistry. By Beckett & Stenlake. Antioxidants. Expectorants. Text book of Pharmaceutical Analysis By Dr. 21 . • Water pollution & Purification techniques Industrial water wastes & pollutants • Sclerosing agents. 2. Dental Products Dentifrices Anticarries agent Theoretical Principals of Qualitative analysis Section II Complexing & Chelating agents other antidotes Radiopharmaceuticals and contrast media: Radiopharmaceuticals.A.T125 PHARMACEUTICAL INORGANIC CHEMISTRY-II (4 Hrs/Week) 1 2 3 4 5 6 6 Section II Topical Agents Protective. astringents. Anesthetics Respiratory stimulants. Anti-infective Gases & Vapors Oxygen. Emetics. 4.
9th edition. 987. “ Bailey`s TextBook of Microscopic Anatomy”. 18th Edition 9) Elaine N. New Delhi. Anatomy and Physiology in health and illness. Health Education. 1997 4th edition. 2002. Medical allied agency. Sherman.Physiological role c) Physiology of menstruation. and Park K. 11) Park J. 4th edition. New Delhi. No of Hrs 1 07 2 08 3 07 4 07 5 05 6 03 03 05 7 8 Books Recommended: 1) Guyton & Hall. 1984. “ Text Book of Human Histology with Colour Atlas. 2000 10th edition.Health Programme in India. Health Planning and Management.E. Chapter The topics which were covered up to 10+2 shuld be covered with more dtails as given in books recommended to increase the depth.J. Human Physiology. New York. Textbook of medical physiology. Nutrition and Health. Physiology and Health Education 45 Hours (3hrs/Week) Sr.. communicable and non communicable diseases.Glomerular apparatuse) Maintenance of Acid-Base balance Respiratory System a) Anatomy of respiratory organs and functions b) Mechanism and regulation of respiration c) Physiology of respiration: Transport of respiratory gases d) Respiratory volumes and vital capacity e) Neural and chemical regulation of respiration O2 and CO2 carriage and hypoxia f) Definitions of Hypoxia. 2nd edition 8) Douglas E. 10) Inderbir Singh. Oxygen Therapy and resuscitation Digestive System a) Anatomy of Gastro intestinal Tract(GIT) b) Anatomy. Intestine c) Digestion and absorption Section-II Reproductive System a) Male and female reproductive systems b) Their hormones. “Human Anatomy and Physiology”. Churchill Living Stone. 1st edition. New Delhi. 1993. New Cenrtal Book Agency. India. Principles of anatomy & physiology. “ Illustrated Physiology”. “Consise Medical Physiology”. 2) Vander.. Harper Collins College Publishers... Pancreas. Secretions and functions of-Salivary glands. 4) Chatterjee C. No. Luciano. Asphyxia .I. Mental Health. Demography and Family Planning. Kolkata 2003 11th Edition. Marieb. Williams and Wilkins publishers.C. Banarasidas Bhanot. 7) Chaudhry Sujit K. Enders. Liver. 13th edition 22 . 5) Ross and Wilson. Dysbarism. Kelly. 6) AB Mc Naught and Callander R. 3) Tortora G. Calcutta. Churchill Livingstone 2001. Elsevier.T126 Human Anatomy. B. . New York 1996 8th edition. Human Physiology. Richard Wood and Allen C. 1991. Jaypee Brothers. London. ovarian cycle d) Spermatogenesis e) Sex determination(genetic basis) f) Pregnancy and its maintenance and parturition g) Contraception and Contraceptive devices Sense Organs a) Eye b) Ear-Hearing and Equillibrium c) Skin d) Taste and smell Skeletal muscles a) Histology b) Physiology of muscle contraction c) Physiological properties of skeletal muscle Fluid & electrolyte balance Health Education. Section-I Urinary System a) Parts of the Urinary System and Gross structure of the kidney b) Structure of Nephron c) Physiology of Urine Formation and Micturition d) Renin Angiotensin System – Juxtra. Addison Wesley. Mc-Graw Hill Publication New Delhi 1998 7th edition. “Preventive and Social Medicine”. Stomach. Occupational Health.
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